A p105-based inhibitor broadly represses NF-kappa B activities (Q40602636)

21 September 2017

A p105-based inhibitor broadly represses NF-kappa B activities (English)

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21 September 2017

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Dexue Fu

1

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21 September 2017

Minae Kobayashi

series ordinal

2

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21 September 2017

Li Lin

series ordinal

3

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21 September 2017

language of work or name

English

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publication date

1 January 2004

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Journal of Biological Chemistry

21 September 2017

8

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based on heuristic

inferred from page(s)

published in

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279

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21 September 2017

13

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21 September 2017

12819-12826

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The NF-kappa B and I kappa B proteins: new discoveries and insights

21 September 2017

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Duration of nuclear NF-kappaB action regulated by reversible acetylation

21 January 2018

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NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

21 January 2018

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Rel/NF-kappa B/I kappa B signal transduction in the generation and treatment of human cancer

21 January 2018

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NF-kappaB in cancer: from innocent bystander to major culprit

21 January 2018

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NF-kappaB at the crossroads of life and death

21 January 2018

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NF-kappaB in cancer: a marked target

21 January 2018

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Aberrant rel/nfkb genes and activity in human cancer

21 January 2018

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TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

21 January 2018

1 reference

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Nuclear factor kappaB-dependent gene expression profiling of Hodgkin's disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity

21 January 2018

1 reference

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Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

Two pathways to NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

Increased expression of p50-NF-kappaB and constitutive activation of NF-kappaB transcription factors during mouse skin carcinogenesis

21 January 2018

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NF-kappaB1 (p50) homodimers contribute to transcription of the bcl-2 oncogene

21 January 2018

1 reference

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The ankyrin repeat domains of the NF-kappa B precursor p105 and the protooncogene bcl-3 act as specific inhibitors of NF-kappa B DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

p105.Ikappa Bgamma and prototypical Ikappa Bs use a similar mechanism to bind but a different mechanism to regulate the subcellular localization of NF-kappa B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

Cotranslational biogenesis of NF-kappaB p50 by the 26S proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

Cotranslational dimerization of the Rel homology domain of NF-kappaB1 generates p50-p105 heterodimers and is required for effective p50 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

Shared pathways of IkappaB kinase-induced SCF(betaTrCP)-mediated ubiquitination and degradation for the NF-kappaB precursor p105 and IkappaBalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

The death domain of NF-kappa B1 p105 is essential for signal-induced p105 proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

NF-kappaB p105 is a target of IkappaB kinases and controls signal induction of Bcl-3-p50 complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

Direct phosphorylation of NF-kappaB1 p105 by the IkappaB kinase complex on serine 927 is essential for signal-induced p105 proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

A glycine-rich region in NF-kappaB p105 functions as a processing signal for the generation of the p50 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

Structural motifs involved in ubiquitin-mediated processing of the NF-kappaB precursor p105: roles of the glycine-rich region and a downstream ubiquitination domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

Eukaryotic expression vectors for the analysis of mutant proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

Blocking caspase-3-mediated proteolysis of IKKbeta suppresses TNF-alpha-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

The absence of NF-kappaB-mediated inhibition of c-Jun N-terminal kinase activation contributes to tumor necrosis factor alpha-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

I kappa B gamma, a 70 kd protein identical to the C-terminal half of p110 NF-kappa B: a new member of the I kappa B family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

The precursor of NF-kappa B p50 has I kappa B-like functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

The PEST-like sequence of I kappa B alpha is responsible for inhibition of DNA binding but not for cytoplasmic retention of c-Rel or RelA homodimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

The 65-kD subunit of NF-kappa B is a receptor for I kappa B and a modulator of DNA-binding specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

NF-kappaB and the innate immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

Innate immune recognition: mechanisms and pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

The MEK/ERK pathway acts upstream of NF kappa B1 (p50) homodimer activity and Bcl-2 expression in a murine B-cell lymphoma cell line. MEK inhibition restores radiation-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

Nuclear import of IkappaBalpha is accomplished by a ran-independent transport pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

The generation of nfkb2 p52: mechanism and efficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

Differential regulation of NF-kappaB2(p100) processing and control by amino-terminal sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

Nuclear factor (NF)-kappa B2 (p100/p52) is required for normal splenic microarchitecture and B cell-mediated immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

Lymphotoxin and lipopolysaccharide induce NF-kappaB-p52 generation by a co-translational mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312572200

Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3

21 January 2018

1 reference

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Structure and function of haemoglobin Barcelona Asp FG1(94) beta leads to His

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M312572200

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21 September 2017

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