The fusion oncoprotein PML-RARalpha induces endoplasmic reticulum (ER)-associated degradation of N-CoR and ER stress. (Q40602763)

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17 November 2019

title

The fusion oncoprotein PML-RARalpha induces endoplasmic reticulum (ER)-associated degradation of N-CoR and ER stress (English)

1 reference

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17 November 2019

main subject

endoplasmic reticulum

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author

Hiderou Yoshida

5

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17 November 2019

Shunsuke Ishii

7

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17 November 2019

author name string

Md Matiullah Khan

1

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17 November 2019

Teruaki Nomura

2

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17 November 2019

Tomoki Chiba

3

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17 November 2019

Keiji Tanaka

4

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17 November 2019

Kazutoshi Mori

6

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17 November 2019

language of work or name

English

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publication date

29 December 2003

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Journal of Biological Chemistry

17 November 2019

published in

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17 November 2019

volume

279

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17 November 2019

issue

12

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17 November 2019

page(s)

11814-11824

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Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

17 November 2019

cites work

1 reference

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The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

21 January 2018

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PML protein isoforms and the RBCC/TRIM motif

21 January 2018

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PML, a growth suppressor disrupted in acute promyelocytic leukemia

21 January 2018

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Role of PML in cell growth and the retinoic acid pathway

21 January 2018

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A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

21 January 2018

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Retinoic acid regulates aberrant nuclear localization of PML-RAR alpha in acute promyelocytic leukemia cells

21 January 2018

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Role of PML and PML-RARalpha in Mad-mediated transcriptional repression

21 January 2018

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PML-RARalpha alleviates the transcriptional repression mediated by tumor suppressor Rb.

21 January 2018

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A RA-dependent, tumour-growth suppressive transcription complex is the target of the PML-RARalpha and T18 oncoproteins

21 January 2018

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PML induces a novel caspase-independent death process

21 January 2018

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PML is essential for multiple apoptotic pathways

21 January 2018

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Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

21 January 2018

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A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression

21 January 2018

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PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

21 January 2018

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Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

21 January 2018

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Role of the histone deacetylase complex in acute promyelocytic leukaemia

21 January 2018

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Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia

21 January 2018

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Posttranslational quality control: folding, refolding, and degrading proteins.

21 January 2018

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Mechanisms underlying ubiquitination

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The action of molecular chaperones in the early secretory pathway

21 January 2018

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Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

21 January 2018

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Combinatorial roles of the nuclear receptor corepressor in transcription and development

21 January 2018

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Intracellular assembly of very low density lipoproteins containing apolipoprotein B100 in rat hepatoma McA-RH7777 cells

21 January 2018

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Quality control in the endoplasmic reticulum: PDI mediates the ER retention of unassembled procollagen C-propeptides

21 January 2018

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A novel Rab6-interacting domain defines a family of Golgi-targeted coiled-coil proteins

21 January 2018

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Oligomerization of RAR and AML1 transcription factors as a novel mechanism of oncogenic activation.

21 January 2018

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Acquisition of oncogenic potential by RAR chimeras in acute promyelocytic leukemia through formation of homodimers.

21 January 2018

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ER-golgi traffic is a prerequisite for efficient ER degradation.

21 January 2018

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ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals

21 January 2018

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An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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c-Fos associates with the endoplasmic reticulum and activates phospholipid metabolism

21 January 2018

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Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M312121200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14701861%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

1 reference