Structural Changes and Proton Transfer in Cytochrome c Oxidase (Q40604277)

22 September 2017

Structural Changes and Proton Transfer in Cytochrome c Oxidase (English)

1 reference

22 September 2017

3

Peter Brzezinski

1 reference

22 September 2017

Jóhanna Vilhjálmsdóttir

series ordinal

1

1 reference

22 September 2017

Ann-Louise Johansson

series ordinal

2

1 reference

22 September 2017

language of work or name

English

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publication date

27 August 2015

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22 September 2017

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22 September 2017

5

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22 September 2017

12047

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Creative Commons Attribution 4.0 International

22 September 2017

start time

27 August 2015

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Changing hydration level in an internal cavity modulates the proton affinity of a key glutamate in cytochrome c oxidase

22 September 2017

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Functions of the hydrophilic channels in protonmotive cytochrome c oxidase.

22 September 2017

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Intermediates generated during the reaction of reduced Rhodobacter sphaeroides cytochrome c oxidase with dioxygen

22 September 2017

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Molecular mechanisms for generating transmembrane proton gradients

22 September 2017

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Gating and regulation of the cytochrome c oxidase proton pump.

22 September 2017

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Coupled electron and proton transfer reactions during the O→E transition in bovine cytochrome c oxidase

22 September 2017

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Cytochrome c oxidase: Intermediates of the catalytic cycle and their energy-coupled interconversion

22 September 2017

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Glu-286 rotation and water wire reorientation are unlikely the gating elements for proton pumping in cytochrome C oxidase

22 September 2017

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Kinetic design of the respiratory oxidases

22 September 2017

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The D-channel of cytochrome oxidase: an alternative view

22 September 2017

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Proton-pumping mechanism of cytochrome C oxidase

22 September 2017

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Exploration of the cytochrome c oxidase pathway puzzle and examination of the origin of elusive mutational effects

22 September 2017

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Crystallographic and online spectral evidence for role of conformational change and conserved water in cytochrome oxidase proton pump

22 September 2017

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Proton-coupled electron transfer in cytochrome oxidase.

22 September 2017

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Decoupling mutations in the D-channel of the aa(3)-type cytochrome c oxidase from Rhodobacter sphaeroides suggest that a continuous hydrogen-bonded chain of waters is essential for proton pumping

22 September 2017

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Bovine cytochrome c oxidase structures enable O 2 reduction with minimization of reactive oxygens and provide a proton-pumping gate

22 September 2017

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Variable proton-pumping stoichiometry in structural variants of cytochrome c oxidase

22 September 2017

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Redox-Dependent Conformational Changes in Cytochrome c Oxidase Suggest a Gating Mechanism for Proton Uptake

22 September 2017

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Electron transfer and energy transduction in the terminal part of the respiratory chain - lessons from bacterial model systems

22 September 2017

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Cytochrome c oxidase: exciting progress and remaining mysteries

22 September 2017

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A D-pathway mutation decouples the Paracoccus denitrificans cytochrome c oxidase by altering the side-chain orientation of a distant conserved glutamate

22 September 2017

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Theoretical and computational analysis of the membrane potential generated by cytochrome c oxidase upon single electron injection into the enzyme.

22 September 2017

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Electrostatic basis for the unidirectionality of the primary proton transfer in cytochrome c oxidase.

22 September 2017

1 reference

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Impaired proton pumping in cytochrome c oxidase upon structural alteration of the D pathway

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

Glutamic acid 242 is a valve in the proton pump of cytochrome c oxidase.

22 September 2017

1 reference

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Molecular mechanism of proton translocation by cytochrome c oxidase

22 September 2017

1 reference

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Exploring the proton pump mechanism of cytochrome c oxidase in real time

22 September 2017

1 reference

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Replacing Asn207 by aspartate at the neck of the D channel in the aa3-type cytochrome c oxidase from Rhodobacter sphaeroides results in decoupling the proton pump

22 September 2017

1 reference

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Mapping protein dynamics in catalytic intermediates of the redox-driven proton pump cytochrome c oxidase

22 September 2017

1 reference

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Chance and design--proton transfer in water, channels and bioenergetic proteins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

Proton pumping mechanism of bovine heart cytochrome c oxidase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

Design principles of proton-pumping haem-copper oxidases

22 September 2017

1 reference

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Energy transduction: proton transfer through the respiratory complexes

22 September 2017

1 reference

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Combined DFT and electrostatics study of the proton pumping mechanism in cytochrome c oxidase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

Controlled uncoupling and recoupling of proton pumping in cytochrome c oxidase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

Electron transfer between hemes in mammalian cytochrome c oxidase.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

Structural elements involved in electron-coupled proton transfer in cytochrome c oxidase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

Time-resolved dynamics of proton transfer in proteinous systems

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

Redox-coupled proton translocation in biological systems: proton shuttling in cytochrome c oxidase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

The low-spin heme of cytochrome c oxidase as the driving element of the proton-pumping process

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

Redox-driven proton pumping by heme-copper oxidases

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

The X-ray crystal structures of wild-type and EQ(I-286) mutant cytochrome c oxidases from Rhodobacter sphaeroides

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

Transient binding of CO to Cu(B) in cytochrome c oxidase is dynamically linked to structural changes around a carboxyl group: a time-resolved step-scan Fourier transform infrared investigation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

On the role of the K-proton transfer pathway in cytochrome c oxidase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

The cytochrome c oxidase from Paracoccus denitrificans does not change the metal center ligation upon reduction

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

Proton uptake controls electron transfer in cytochrome c oxidase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

Internal electron-transfer reactions in cytochrome c oxidase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

Proton-transport mechanisms in cytochrome c oxidase revealed by studies of kinetic isotope effects

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

Overexpression and purification of cytochrome c oxidase from Rhodobacter sphaeroides

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

Proton pumping in cytochrome c oxidase: energetic requirements and the role of two proton channels

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

The identity of the transient proton loading site of the proton-pumping mechanism of cytochrome c oxidase

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

A pathogenic mutation in cytochrome c oxidase results in impaired proton pumping while retaining O(2)-reduction activity

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

Structural elements involved in proton translocation by cytochrome c oxidase as revealed by backbone amide hydrogen-deuterium exchange of the E286H mutant

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

Two conformational states of Glu242 and pKas in bovine cytochrome c oxidase

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

A mechanistic principle for proton pumping by cytochrome c oxidase

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

Water chain formation and possible proton pumping routes in Rhodobacter sphaeroides cytochrome c oxidase: a molecular dynamics comparison of the wild type and R481K mutant

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

The protonation state of a heme propionate controls electron transfer in cytochrome c oxidase

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

Electrostatic study of the proton pumping mechanism in bovine heart cytochrome C oxidase

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

Intramolecular proton-transfer reactions in a membrane-bound proton pump: the effect of pH on the peroxy to ferryl transition in cytochrome c oxidase

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4550891

Structure and dynamics of a proton shuttle in cytochrome c oxidase

20 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSREP12047

Reaction of wild-type and Glu243Asp variant yeast cytochrome c oxidase with O2

21 January 2018

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12 December 2020

Internal electron transfer in cytochrome c oxidase from Rhodobacter sphaeroides

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12 December 2020

Factors determining electron-transfer rates in cytochrome c oxidase: investigation of the oxygen reaction in the R. sphaeroides enzyme

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12 December 2020

Tracing the D-pathway in reconstituted site-directed mutants of cytochrome c oxidase from Paracoccus denitrificans

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12 December 2020

The inside pH determines rates of electron and proton transfer in vesicle-reconstituted cytochrome c oxidase

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12 December 2020

Electrostatic control of proton pumping in cytochrome c oxidase

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12 December 2020

Transmembrane charge separation during the ferryl-oxo -> oxidized transition in a nonpumping mutant of cytochrome c oxidase

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12 December 2020

Rapid purification of wildtype and mutant cytochrome c oxidase from Rhodobacter sphaeroides by Ni(2+)-NTA affinity chromatography

1 reference

12 December 2020

Involvement of Glutamic Acid 278 in the Redox Reaction of the CytochromecOxidase fromParacoccus denitrificansInvestigated by FTIR Spectroscopy†

1 reference

12 December 2020

Electron transfer induces side-chain conformational changes of glutamate-286 from cytochrome bo3

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12 December 2020

Identifiers

DOI

10.1038/SREP12047

1 reference

22 September 2017

1 reference

22 September 2017

PubMed publication ID

26310633

1 reference