Critical role of STAT5 activation in transformation mediated by ZNF198-FGFR1. (Q40609712)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14660670%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

Critical role of STAT5 activation in transformation mediated by ZNF198-FGFR1 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14660670%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14660670%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

author name string

Carol Heath

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14660670%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

language of work or name

English

0 references

publication date

5 December 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14660670%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

21 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14660670%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

volume

279

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14660670%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14660670%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

page(s)

6666-6673

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14660670%20AND%20SRC:MED&resulttype=core&format=json

The 8p11 myeloproliferative syndrome: a distinct clinical entity caused by constitutive activation of FGFR1

21 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308743200

FGFR1 is fused with a novel zinc-finger gene, ZNF198, in the t(8;13) leukaemia/lymphoma syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308743200

The t(8;13)(p11;q11-12) rearrangement associated with an atypical myeloproliferative disorder fuses the fibroblast growth factor receptor 1 gene to a novel gene RAMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308743200

Characterization of FIM-FGFR1, the fusion product of the myeloproliferative disorder-associated t(8;13) translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308743200

The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: transforming activity and specific inhibition of FGFR1 fusion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308743200

The oncogenic fusion protein-tyrosine kinase ZNF198/fibroblast growth factor receptor-1 has signaling function comparable with interleukin-6 cytokine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308743200

Fusion of the BCR and the fibroblast growth factor receptor-1 (FGFR1) genes as a result of t(8;22)(p11;q11) in a myeloproliferative disorder: the first fusion gene involving BCR but not ABL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308743200

Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308743200

P210 and P190(BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308743200

The TEL/PDGFbetaR fusion in chronic myelomonocytic leukemia signals through STAT5-dependent and STAT5-independent pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308743200

Constitutive activation of STAT3 and STAT5 is induced by leukemic fusion proteins with protein tyrosine kinase activity and is sufficient for transformation of hematopoietic precursor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308743200

Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308743200

Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308743200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308743200

Signal transducer and activator of transcription proteins in leukemias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308743200

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308743200

Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308743200

FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308743200

ZNF198-FGFR1 transforms Ba/F3 cells to growth factor independence and results in high level tyrosine phosphorylation of STATS 1 and 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308743200

Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308743200

Fusion tyrosine kinases induce drug resistance by stimulation of homology-dependent recombination repair, prolongation of G(2)/M phase, and protection from apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308743200

8p12 stem cell myeloproliferative disorder: the FOP-fibroblast growth factor receptor 1 fusion protein of the t(6;8) translocation induces cell survival mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt/mTOR pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308743200

Stat5 is essential for the myelo- and lymphoproliferative disease induced by TEL/JAK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308743200

21 January 2018

Identifiers

DOI

10.1074/JBC.M308743200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14660670%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference