Active and inactive orientations of the transmembrane and cytosolic domains of the erythropoietin receptor dimer (Q40613603)

22 September 2017

title

Active and inactive orientations of the transmembrane and cytosolic domains of the erythropoietin receptor dimer (English)

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22 September 2017

main subject

transmembrane protein

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Shyam S. Krishnakumar

6

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22 September 2017

Stefan N Constantinescu

8

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22 September 2017

Nadine Seubert

1

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22 September 2017

Yohan Royer

2

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22 September 2017

Judith Staerk

3

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22 September 2017

Katharina F Kubatzky

4

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22 September 2017

Virginie Moucadel

5

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22 September 2017

Steven O Smith

7

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22 September 2017

publication date

1 November 2003

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22 September 2017

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22 September 2017

volume

12

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22 September 2017

issue

5

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22 September 2017

page(s)

1239-1250

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Interhelical hydrogen bonds and spatial motifs in membrane proteins: polar clamps and serine zippers

22 September 2017

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PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

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Tyrosine Residues within the Intracellular Domain of the Erythropoietin Receptor Mediate Activation of AP-1 Transcription Factors

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Imitation of Escherichia coli aspartate receptor signaling in engineered dimers of the cytoplasmic domain

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Activation of the erythropoietin receptor by the gp55-P viral envelope protein is determined by a single amino acid in its transmembrane domain

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7 January 2021

The erythropoietin receptor cytosolic juxtamembrane domain contains an essential, precisely oriented, hydrophobic motif

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7 January 2021

Ligand-independent oligomerization of cell-surface erythropoietin receptor is mediated by the transmembrane domain

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Phosphorylation of tyrosine 503 in the erythropoietin receptor (EpR) is essential for binding the P85 subunit of phosphatidylinositol (PI) 3-kinase and for EpR-associated PI 3-kinase activity

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Tyrosine 343 in the erythropoietin receptor positively regulates erythropoietin-induced cell proliferation and Stat5 activation.

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Expression cloning of the murine erythropoietin receptor

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Activation of the erythropoietin (EPO) receptor by bivalent anti-EPO receptor antibodies

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The signal transduction pathway of erythropoietin involves three forms of mitogen-activated protein (MAP) kinase in UT7 erythroleukemia cells

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A heptad motif of leucine residues found in membrane proteins can drive self-assembly of artificial transmembrane segments

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The N-terminal domain of Janus kinase 2 is required for Golgi processing and cell surface expression of erythropoietin receptor

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Identification of the human erythropoietin receptor region required for Stat1 and Stat3 activation

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Multiple tyrosine residues in the cytosolic domain of the erythropoietin receptor promote activation of STAT5.

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Identification of a novel pathway important for proliferation and differentiation of primary erythroid progenitors

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7 January 2021

Self assembly of the transmembrane domain promotes signal transduction through the erythropoietin receptor

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7 January 2021

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An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for activation

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Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A

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A cellular reporter assay to monitor insulin receptor kinase activity based on STAT 5-dependent luciferase gene expression

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Crystal structure of a PUT3-DNA complex reveals a novel mechanism for DNA recognition by a protein containing a Zn2Cys6 binuclear cluster

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7 January 2021

Efficiency of signalling through cytokine receptors depends critically on receptor orientation

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7 January 2021

Structure and mobility of the PUT3 dimer

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JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

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Small peptides as potent mimetics of the protein hormone erythropoietin

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7 January 2021

Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor

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7 January 2021

Point mutation in the exoplasmic domain of the erythropoietin receptor resulting in hormone-independent activation and tumorigenicity

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7 January 2021

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Identifiers

DOI

1 reference

22 September 2017

1 reference