Constitutively active Galpha16 stimulates STAT3 via a c-Src/JAK- and ERK-dependent mechanism (Q40627260)

22 September 2017

Constitutively active Galpha16 stimulates STAT3 via a c-Src/JAK- and ERK-dependent mechanism (English)

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22 September 2017

3

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22 September 2017

Rico K H Lo

1

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PubMed ID

14551213

22 September 2017

Helen Cheung

series ordinal

2

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PubMed ID

14551213

22 September 2017

language of work or name

English

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publication date

9 October 2003

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Journal of Biological Chemistry

22 September 2017

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22 September 2017

278

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22 September 2017

52154-52165

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22 September 2017

52

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Two G protein oncogenes in human endocrine tumors

22 September 2017

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A mutant alpha subunit of Gi2 induces neoplastic transformation of Rat-1 cells

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GTPase-deficient G alpha 16 and G alpha q induce PC12 cell differentiation and persistent activation of cJun NH2-terminal kinases

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Stat3-mediated transformation of NIH-3T3 cells by the constitutively active Q205L Galphao protein.

21 January 2018

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STATs and gene regulation

21 January 2018

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

21 January 2018

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Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

21 January 2018

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Activation and association of Stat3 with Src in v-Src-transformed cell lines

21 January 2018

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c-Src activates both STAT1 and STAT3 in PDGF-stimulated NIH3T3 cells

21 January 2018

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STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation

21 January 2018

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Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein

21 January 2018

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Regulation of angiotensin II-induced phosphorylation of STAT3 in vascular smooth muscle cells

21 January 2018

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Binding of alpha-melanocyte-stimulating hormone to its G-protein-coupled receptor on B-lymphocytes activates the Jak/STAT pathway

21 January 2018

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Linkage between alpha(1) adrenergic receptor and the Jak/STAT signaling pathway in vascular smooth muscle cells

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G protein coupled receptor signaling through the Src and Stat3 pathway: role in proliferation and transformation

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Regulation by Gi2 proteins of v-fms-induced proliferation and transformation via Src-kinase and STAT3.

21 January 2018

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G alpha 16, a G protein alpha subunit specifically expressed in hematopoietic cells

21 January 2018

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G alpha 15 and G alpha 16 couple a wide variety of receptors to phospholipase C

21 January 2018

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Melatonin mt1 and MT2 receptors stimulate c-Jun N-terminal kinase via pertussis toxin-sensitive and -insensitive G proteins

21 January 2018

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Serine phosphorylation and negative regulation of Stat3 by JNK

21 January 2018

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Regulation of STAT3 activity by G16-coupled receptors

21 January 2018

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Rac and Cdc42-dependent regulation of c-Jun N-terminal kinases by the delta-opioid receptor

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Protein Kinase C- (PKC- ): Its Unique Structure and Function

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Possible role of Ca2(+)-independent protein kinase C isozyme, nPKC epsilon, in thyrotropin-releasing hormone-stimulated signal transduction: differential down-regulation of nPKC epsilon in GH4C1 cells

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Role of Janus kinase/signal transducer and activator of transcription and mitogen-activated protein kinase cascades in angiotensin II- and platelet-derived growth factor-induced vascular smooth muscle cell proliferation.

21 January 2018

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Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

21 January 2018

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Stat3 activation by Src induces specific gene regulation and is required for cell transformation

21 January 2018

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A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

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Src tyrosine kinase is a novel direct effector of G proteins.

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Identification of Tetratricopeptide Repeat 1 as an Adaptor Protein That Interacts with Heterotrimeric G Proteins and the Small GTPase Ras

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G alpha 16 couples chemoattractant receptors to NF-kappa B activation

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Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

21 January 2018

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Regulation of Stat3 activation by MEK kinase 1.

21 January 2018

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Rho family GTPases are required for activation of Jak/STAT signaling by G protein-coupled receptors

21 January 2018

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Regulation of STAT3 by direct binding to the Rac1 GTPase

21 January 2018

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Leukotriene B(4) stimulates Rac-ERK cascade to generate reactive oxygen species that mediates chemotaxis

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Integration of signals from receptor tyrosine kinases and g protein-coupled receptors.

21 January 2018

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Group I metabotropic glutamate receptors control phosphorylation of CREB, Elk-1 and ERK via a CaMKII-dependent pathway in rat striatum

21 January 2018

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CaM kinase II-dependent activation of tyrosine kinases and ERK1/2 in vascular smooth muscle

21 January 2018

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Dependence of gonadotropin-releasing hormone-induced neuronal MAPK signaling on epidermal growth factor receptor transactivation

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Intracellular signaling pathways mediated by the gonadotropin-releasing hormone (GnRH) receptor

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Bradykinin B2 receptor-mediated proliferation via activation of the Ras/Raf/MEK/MAPK pathway in rat vascular smooth muscle cells

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Activation of RAF-1 through Ras and protein kinase Calpha mediates 1alpha,25(OH)2-vitamin D3 regulation of the mitogen-activated protein kinase pathway in muscle cells

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Cholecystokinin stimulates extracellular signal-regulated kinase through activation of the epidermal growth factor receptor, Yes, and protein kinase C. Signal amplification at the level of Raf by activation of protein kinase Cepsilon

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Activation of Stat3 in v-Src-transformed fibroblasts requires cooperation of Jak1 kinase activity

21 January 2018

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Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases

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21 January 2018

Identifiers

DOI

10.1074/JBC.M307299200

1 reference

22 September 2017

1 reference

PubMed ID

14551213