Drug and radiation resistance in spheroids: cell contact and kinetics (Q40630918)

22 September 2017

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title

Drug and radiation resistance in spheroids: cell contact and kinetics (English)

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22 September 2017

P L Olive

1

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22 September 2017

R E Durand

series ordinal

2

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22 September 2017

language of work or name

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1 June 1994

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Cancer and Metastasis Reviews

22 September 2017

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22 September 2017

13

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22 September 2017

2

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22 September 2017

121-138

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https://scigraph.springernature.com/pub.10.1007/bf00689632

22 September 2017

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cites work

Use of Hoechst 33342 for cell selection from multicell systems

1 reference

https://api.crossref.org/works/10.1007%2FBF00689632

Effects of doxorubicin and cisplatin on multicellular tumor spheroids from human lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00689632

In vitro chemosensitivity testing using the multicellular tumor spheroid model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00689632

Cisplatin and CCNU synergism in spheroid cell subpopulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00689632

Cell-cell contact affects cellular sensitivity to hyperthermia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00689632

Size-dependent resistance of human tumour spheroids to photodynamic treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00689632

Adriamycin: A Possible Indirect Radiosensitizer of Hypoxic Tumor Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00689632

Cell killing and DNA damage by etoposide in Chinese hamster V79 monolayers and spheroids: influence of growth kinetics, growth environment and DNA packaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00689632

Matrix attachment regions are positioned near replication initiation sites, genes, and an interamplicon junction in the amplified dihydrofolate reductase domain of Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00689632

Relationship between topoisomerase II and radiosensitivity in mouse L5178Y lymphoma strains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00689632

Enhancement of transforming growth factor-alpha synthesis in multicellular tumour spheroids of A431 squamous carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00689632

Effect of cell-cell and cell-matrix interactions on the response of fibroblasts to epidermal growth factor in vitro. Expression of collagen type I, collagenase, stromelysin and tissue inhibitor of metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00689632

Laser flow cytometry and cancer chemotherapy: detection of intracellular anthracyclines by flow cytometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00689632

Isolation of Chinese hamster ovary cells with reduced poly(ADP-ribose) polymerase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00689632

The lower radiosensitivity of mouse kidney cells irradiated in vivo than in vitro: A cell contact effect phenomenon

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00689632

Morphological transformation of Chinese hamster cells by dibutyryl adenosine cyclic 3':5'-monophosphate and testosterone

21 January 2018

1 reference

12 December 2020

Effect of intercellular contact on DNA conformation, radiation-induced DNA damage, and mutation in Chinese hamster V79 cells

1 reference

12 December 2020

Repair during multifraction exposures: spheroids versus monolayers

1 reference

12 December 2020

Repair of radiation damage in noncycling parenchymal hepatocytes

1 reference

12 December 2020

Preferential, cooperative binding of DNA topoisomerase II to scaffold-associated regions

1 reference

12 December 2020

Increased radioresistance of cells in cultured multicell spheroids. I. Dependence on cellular interaction

1 reference

12 December 2020

Extracellular matrices in multicellular spheroids of human glioma origin: increased incorporation of proteoglycans and fibronectin as compared to monolayer cultures

1 reference

12 December 2020

Increased accessibility of bases in DNA upon binding of acridine orange

1 reference

12 December 2020

Relations between the penetration, binding and average concentration of cytostatic drugs in human tumour spheroids

1 reference

12 December 2020

Detection of ionizing radiation-induced DNA double-strand breaks by filter elution is affected by nuclear chromatin structure.

1 reference

12 December 2020

The relationship between tumour geometry and the response of tumour cells to cytotoxic drugs--an in vitro study using EMT6 multicellular spheroids

1 reference

12 December 2020

Protein synthesis requires cell-surface contact while nuclear events respond to cell shape in anchorage-dependent fibroblasts

1 reference

12 December 2020

Growth of nodular carcinomas in rodents compared with multi-cell spheroids in tissue culture

1 reference

12 December 2020

Application of theoretical models to chemotherapy protocol design

1 reference

12 December 2020

Supercoils in human DNA

1 reference

12 December 2020

Flow cytometry studies of intracellular adriamycin in multicell spheroids in vitro

1 reference

12 December 2020

Hyperthermia Blocks DNA Processing at the Nuclear Matrix

1 reference

12 December 2020

Slow penetration of anthracyclines into spheroids and tumors: a therapeutic advantage?

1 reference

12 December 2020

Is there a relationship between hypoxia, contact resistance, and intercellular communication?

1 reference

12 December 2020

Intercellular Communication in Spheroids

1 reference

12 December 2020

Neutral filter elution detects differences in chromatin organization which can influence cellular radiosensitivity

1 reference

12 December 2020

Modulation of chromatin superstructure induced by poly(ADP-ribose) synthesis and degradation

1 reference

12 December 2020

Increased thermoresistance developed during growth of small multicellular spheroids.

1 reference

12 December 2020

Radiation-induced division delay in 9L spheroid versus monolayer cells

1 reference

12 December 2020

The role of membranes in the mechanism of action of the antineoplastic agent adriamycin. Spin-labeling studies with chronically hypoxic and drug-resistant tumor cells.

1 reference

12 December 2020

Evidence for a Unique in Situ Component of the Repair of Radiation Damage

1 reference

12 December 2020

Cytotoxicity of RSU 1069 in spheroids and murine tumors

1 reference

12 December 2020

Denaturation and condensation of DNA in situ induced by acridine orange in relation to chromatin changes during growth and differentiation of Friend erythroleukemia cells

1 reference

12 December 2020

A Comparative Study of Post-irradiation Growth Kinetics of Spheroids and Monolayers

1 reference

12 December 2020

Average relative dose intensity and the impact on design of clinical trials.

1 reference

12 December 2020

Multicellular tumor spheroids in radiotherapy research (review).

1 reference

12 December 2020

The nuclear protein matrix: isolation, structure, and functions

1 reference

12 December 2020

Variations in several responses of HeLa cells to x-irradiation during the division cycle

1 reference

12 December 2020

Effects of lucanthone on Chinese hamster V-79 cells. I. Interaction with radiation in monolayers and spheroids

1 reference

12 December 2020

Radiation studies with spheroids.

1 reference

12 December 2020

Doxorubicin (adriamycin): a critical review of free radical-dependent mechanisms of cytotoxicity

1 reference

12 December 2020

Physical basis for detection of DNA double-strand breaks using neutral filter elution

1 reference

12 December 2020

Cytotoxicity of adriamycin in MGH-U1 cells grown as monolayer cultures, spheroids, and xenografts in immune-deprived mice

1 reference

12 December 2020

Predominant role for DNA damage in etoposide-induced cytotoxicity and cell cycle perturbation in human SV40-transformed fibroblasts.

1 reference

12 December 2020

A mathematic model for relating the drug sensitivity of tumors to their spontaneous mutation rate

1 reference

12 December 2020

Hypoxic cells in an in vitro tumour model

1 reference

12 December 2020

Role of cell shape in growth control

1 reference

12 December 2020

Effects of hyperthermia on the cycling, noncycling, and hypoxic cells of irradiated and unirradiated multicell spheroids

1 reference

12 December 2020

Tumor resistance to therapy: a genetic or kinetic problem?

1 reference

12 December 2020

Organization of the higher-order chromatin loop: specific DNA attachment sites on nuclear scaffold

1 reference

12 December 2020

Hypothesis on Differentiation and the Inheritance of Gene Superstructure

1 reference

12 December 2020

Effects of intercellular contact on repair of radiation damage

1 reference

12 December 2020

The survival of thyroid cells: in vivo irradiation and in situ repair

1 reference

12 December 2020

Heat shock proteins: role in thermotolerance, drug resistance, and relationship to DNA topoisomerases

1 reference

12 December 2020

Cell proliferation as a requirement for development of the contact effect in Chinese hamster V79 spheroids

1 reference

12 December 2020

The influence of cell-cell contact on radiosensitivity of human squamous carcinoma cells.

1 reference

12 December 2020

Acquired multicellular-mediated resistance to alkylating agents in cancer

1 reference

12 December 2020

TGF-beta gene expression depends on tissue architecture

1 reference

12 December 2020

Tumour cell kinetics and heterogeneity: insights from multicell spheroids

1 reference

12 December 2020

The importance of dose intensity in the outcome of chemotherapy

1 reference

12 December 2020

Tumor cell instability, diversification, and progression to the metastatic phenotype: from oncogene to oncofetal expression

1 reference

12 December 2020

Distribution and activity of antineoplastic drugs in a tumor model

1 reference

12 December 2020

Growth of multicell spheroids in tissue culture as a model of nodular carcinomas

1 reference

12 December 2020

Increased radioresistance of cells in cultured multicell spheroids. II. Kinetic and cytogenetic studies

1 reference

12 December 2020

Radiation-Induced DNA Damage in V79 Spheroids and Monolayers

1 reference

12 December 2020

Cell Kinetics and Repopulation During Multifraction Irradiation of Spheroids: Implications for Clinical Radiotherapy

1 reference

12 December 2020

X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution

1 reference

12 December 2020

Relationship between intercellular communication and radiosensitivity of human tumor xenografts.

1 reference

12 December 2020

Heterogeneous DNA damage and repair in the mammalian genome

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12 December 2020

Effects of 5-fluorouracil and leucovorin in spheroids: a model for solid tumours

1 reference

12 December 2020

Resistance of MGH-U1 bladder cancer spheroids to vincristine.

1 reference

12 December 2020

Poly(ADP-ribose) synthase is the major endogenous nonhistone acceptor for poly(ADP-ribose) in alkylated rat hepatoma cells

1 reference

12 December 2020

Gap junction function and cancer.

1 reference

12 December 2020

Flow cytometry studies of intracellular adriamycin in single cells in vitro

1 reference

12 December 2020

Effects of vinblastine and 5-fluorouracil on human glioma and thyroid cancer cell monolayers and spheroids

1 reference

12 December 2020

Differences in the DNA Supercoiling Response of Irradiated Cell Lines from Ataxia-telangiectasia Versus Unaffected Individuals

1 reference

12 December 2020

Chemosensitivity testing in V79 spheroids: drug delivery and cellular microenvironment

1 reference

12 December 2020

Radioresistance of rat glioma cell lines cultured as multicellular spheroids. Correlation with electrical cell-to-cell-coupling.

1 reference

12 December 2020

Determination of cellular shape by the extracellular matrix and its correlation with the control of cellular growth

1 reference

12 December 2020

DNA organization affects cellular radiosensitivity and detection of initial DNA strand breaks

1 reference

12 December 2020

Importance of tyrosine phosphatases in the effects of cell‐cell contact and microenvironments on EGF‐stimulated tyrosine phosphorylation

1 reference

12 December 2020

Cell cycle kinetics in an in vitro tumor model

1 reference

12 December 2020

Radiation sensitivity of human ovarian carcinoma cell lines in vitro: effects of growth factors and hormones, basement membrane, and intercellular contact

1 reference

12 December 2020

Progressive loss of shape-responsive metabolic controls in cells with increasingly transformed phenotype

1 reference

12 December 2020

Epithelial layer formation in differentiating aggregates of F9 embryonal carcinoma cells

1 reference

12 December 2020

DNA conformation of Chinese hamster V79 cells and sensitivity to ionizing radiation

1 reference

12 December 2020

Induction characteristics of oxygen regulated proteins

1 reference

12 December 2020

Development of tetraploidy in V79 spheroids

1 reference

12 December 2020

Etoposide Sensitivity and Topoisomerase II Activity in Chinese Hamster V79 Monolayers and Small Spheroids

1 reference

12 December 2020

Hypersensitivity of cultured ataxia-telangiectasia cells to etoposide

1 reference

12 December 2020

Cell and environment interactions in tumor microregions: the multicell spheroid model

1 reference

12 December 2020

Decreased nuclear matrix DNA topoisomerase II in human leukemia cells resistant to VM-26 and m-AMSA.

1 reference

12 December 2020

The repair of double-strand DNA breaks correlates with radiosensitivity of L5178Y-S and L5178Y-R cells.

1 reference

12 December 2020

The increase in radioresistance of Chinese hamster cells cultured as spheroids is correlated to changes in nuclear morphology

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12 December 2020

Studies on the radiobiology of a rat sarcoma treated in situ and assayed in vitro.

1 reference

12 December 2020

The radiation response of a human colon adenocarcinoma grown in monolayer, as spheroids, and in nude mice.

1 reference

12 December 2020

A further insight into the mechanism of action of anthracycline antibiotics

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12 December 2020

Differential control of cytokeratins and vimentin synthesis by cell-cell contact and cell spreading in cultured epithelial cells

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12 December 2020

Association between radiation sensitivity, DNA repair and chromosome organization in the Chinese hamster ovary cell line xrs-5.

1 reference

12 December 2020

Radiation response of multicell spheroids--an in vitro tumour model

1 reference

12 December 2020

Effects of microtubule inhibitors on etoposide accumulation and DNA damage in human K562 cells in vitro

1 reference

12 December 2020

Influences of growth conditions and cell-cell contact on responses of tumor cells to ultrasound

1 reference

12 December 2020

Topoisomerase II is a structural component of mitotic chromosome scaffolds.

1 reference

12 December 2020

Increased dose-rate effect in V79-multicellular aggregates (spheroids). Relation to initial DNA lesions and repair

1 reference

12 December 2020

Tumour spheroid technology in cancer therapy research

1 reference

12 December 2020

The Effect of Intercellular Contact on the Radiation Sensitivity of KHT Sarcoma Cells

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12 December 2020

DNA repair and the role of chromatin structure

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12 December 2020

Multicell spheroids as a model for cell kinetic studies

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12 December 2020

Radiation-induced DNA unwinding is influenced by cell shape and trypsin

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12 December 2020

Use of a cell sorter for assays of cell clonogenicity

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12 December 2020

Epidermal growth factor reduces resistance to doxorubicin

1 reference

12 December 2020

Resistance to DNA denaturation in irradiated Chinese hamster V79 fibroblasts is linked to cell shape

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12 December 2020

Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons

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12 December 2020

Resistance to adriamycin in multicellular spheroids

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12 December 2020

Further evidence for the involvement of gap-junctional intercellular communication in induction and maintenance of transformed foci in BALB/c 3T3 cells.

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12 December 2020

Serum, trypsin, and cell shape but not cell-to-cell contact influence the X-ray sensitivity of Chinese hamster V79 cells in monolayers and in spheroids

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12 December 2020

DNA double-strand break repair pathways and cellular tolerance to inhibitors of topoisomerase II.

1 reference

12 December 2020

Intercellular contact and the radiation response of cells of human melanoma xenografts

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12 December 2020

Gap junctional intercellular communication and carcinogenesis

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12 December 2020

Factors influencing DNA migration from individual cells subjected to gel electrophoresis

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12 December 2020

Activity of 4'-(9-acridinylamino)methanesulfon-m-anisidide against Chinese hamster cells in multicellular spheroids.

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12 December 2020

Animal cell shape changes and gene expression

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12 December 2020

Hypersensitivity of DNA in transcriptionally active chromatin to ionizing radiation

1 reference

12 December 2020

A comparison of adriamycin and mAMSA. II. Studies with V79 and human tumour multicellular spheroids.

1 reference

12 December 2020

Schedule dependence for cisplatin and etoposide multifraction treatments of spheroids

1 reference

12 December 2020

Penetration and binding of vinblastine and 5-fluorouracil in cellular spheroids.

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00689632

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Dimensions Publication ID

22 September 2017

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