Antifungal properties of the immunosuppressant FK-506: identification of an FK-506-responsive yeast gene distinct from FKB1 (Q40640423)

22 September 2017

Antifungal properties of the immunosuppressant FK-506: identification of an FK-506-responsive yeast gene distinct from FKB1 (English)

1 reference

Crossref

DOI

https://api.crossref.org/works/10.1128/MCB.11.9.4616-4626.1991

6 November 2022

1 reference

1 reference

https://api.crossref.org/works/10.1128/MCB.11.9.4616-4626.1991

6 November 2022

author name string

L. Brizuela

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1715022

6 November 2022

G. Chrebet

2

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6 November 2022

K. A. Bostian

3

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6 November 2022

S. A. Parent

4

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6 November 2022

language of work or name

English

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publication date

1 September 1991

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PMCID

361345

full work available at URL

22 September 2017

http://mcb.asm.org/cgi/content/abstract/11/9/4616

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open access

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1715022/pdf/?tool=EBI

6 November 2022

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open access

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1715022/?tool=EBI

6 November 2022

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https://europepmc.org/articles/PMC361345

6 November 2022

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https://europepmc.org/articles/PMC361345?pdf=render

6 November 2022

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Portable Document Format

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content deliverer

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https://journals.asm.org/doi/pdf/10.1128/mcb.11.9.4616-4626.1991

6 November 2022

1 reference

Crossref

DOI

https://api.crossref.org/works/10.1128/MCB.11.9.4616-4626.1991

Molecular and Cellular Biology

6 November 2022

published in

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22 September 2017

11

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22 September 2017

9

1 reference

22 September 2017

4616-4626

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Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcription

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

[12] One-step gene disruption in yeast

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

Cyclophilin: a specific cytosolic binding protein for cyclosporin A

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

Genetic analysis of streptomycin dependence in Escherichia coli

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

Genetic analysis of streptomycin resistance in Escherichia coli

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

The effects of cyclosporin A on the immune system

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

The multidrug resistance gene PDR1 from Saccharomyces cerevisiae.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

Yeast cyclophilin: isolation and characterization of the protein, cDNA and gene

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

Drosophila ninaA gene encodes an eye-specific cyclophilin (cyclosporine A binding protein)

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

FK 506 for liver, kidney, and pancreas transplantation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

FK-506--how much potential?

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

Cloning by gene amplification of two loci conferring multiple drug resistance in Saccharomyces

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

FKB1 encodes a nonessential FK 506-binding protein in Saccharomyces cerevisiae and contains regions suggesting homology to the cyclophilins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

The cytosolic-binding protein for the immunosuppressant FK-506 is both a ubiquitous and highly conserved peptidyl-prolyl cis-trans isomerase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

Observations on the mechanism of action of FK-506. A pharmacologic probe of lymphocyte signal transduction

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

Catalysis of protein folding by prolyl isomerase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

Allelism of pleiotropic drug resistance in Saccharomyces cerevisiae.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

Hyper-accurate ribosomes inhibit growth

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

Altered Ribosomal Protein in Streptomycin-Dependent Escherichia coli

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

Cyclophilin: distribution and variant properties in normal and neoplastic tissues.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

How do combinations of rpsL- and miaA- generate streptomycin dependence?

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

Genetic mapping of nuclear mucidin resistance mutations in Saccharomyces cerevisiae. A new pdr locus on chromosome II.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

Cyclosporin A-binding protein (cyclophilin) of Neurospora crassa. One gene codes for both the cytosolic and mitochondrial forms.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

Sensitivity to cyclosporin A is mediated by cyclophilin in Neurospora crassa and Saccharomyces cerevisiae.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

The ninaA gene required for visual transduction in Drosophila encodes a homologue of cyclosporin A-binding protein

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

The immunosuppressive macrolides FK-506 and rapamycin act as reciprocal antagonists in murine T cells.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

Physicochemical properties of FK-506, a novel immunosuppressant isolated from Streptomyces tsukubaensis

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

Distinct mechanisms of suppression of murine T cell activation by the related macrolides FK-506 and rapamycin

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=361345

The immunosuppressant FK506 selectively inhibits expression of early T cell activation genes

20 August 2018

1 reference

12 December 2020

Effect of a new immunosuppressive agent, FK506, on human lymphocyte responses in vitro. II. Inhibition of the production of IL-2 and gamma-IFN, but not B cell-stimulating factor 2

1 reference

12 December 2020

Novel immunosuppressive agent, FK506. In vitro effects on the cloned T cell activation

1 reference

12 December 2020

FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro

1 reference

12 December 2020

Control of yeast cell type by the mating type locus. I. Identification and control of expression of the a-specific gene BAR1

1 reference

12 December 2020

Inhibition of the immune response by rapamycin, a new antifungal antibiotic

1 reference

12 December 2020

Application of microtitration techniques to bacteriostatic and bactericidal antibiotic susceptibility testing

1 reference

12 December 2020

Streptomycin preferentially perturbs ribosomal proofreading

1 reference

12 December 2020

Cyclosporine, FK506, and rapamycin. Some effects on early activation events in serum-free, mitogen-stimulated mouse spleen cells

1 reference

12 December 2020

FK-506, a potent novel immunosuppressive agent, binds to a cytosolic protein which is distinct from the cyclosporin A-binding protein, cyclophilin

1 reference

12 December 2020

Isolation and sequence of an FK506-binding protein from N. crassa which catalyses protein folding

1 reference

12 December 2020

FK-506 enters the clinic

1 reference

12 December 2020

One-step gene disruption in yeast

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.11.9.4616

1 reference

PMCID

361345

22 September 2017

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1715022

6 November 2022

1 reference

22 September 2017

1 reference

PMCID

361345