Growth factor receptor-binding protein 10 (Grb10) as a partner of phosphatidylinositol 3-kinase in metabolic insulin action (Q40642763)

22 September 2017

Growth factor receptor-binding protein 10 (Grb10) as a partner of phosphatidylinositol 3-kinase in metabolic insulin action (English)

1 reference

22 September 2017

Youping Deng

1

1 reference

22 September 2017

Sujoy Bhattacharya

2

1 reference

22 September 2017

O Rama Swamy

3

1 reference

22 September 2017

Ruchi Tandon

4

1 reference

22 September 2017

Yong Wang

5

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22 September 2017

Robert Janda

6

1 reference

22 September 2017

Heimo Riedel

7

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22 September 2017

language of work or name

English

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publication date

3 June 2003

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Journal of Biological Chemistry

22 September 2017

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22 September 2017

278

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22 September 2017

41

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22 September 2017

39311-39322

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Grb-IR: a SH2-domain-containing protein that binds to the insulin receptor and inhibits its function

22 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Interaction between the Grb10 SH2 domain and the insulin receptor carboxyl terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Human GRB-IRbeta/GRB10. Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Cloning, chromosome localization, expression, and characterization of an Src homology 2 and pleckstrin homology domain-containing insulin receptor binding protein hGrb10gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

The adapter protein Grb10 associates preferentially with the insulin receptor as compared with the IGF-I receptor in mouse fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Assignment of growth factor receptor-bound protein 10 (GRB10) to human chromosome 7p11.2-p12

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Genomic structure of the gene for the SH2 and pleckstrin homology domain-containing protein GRB10 and evaluation of its role in Hirschsprung disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Identification of the Meg1/Grb10 imprinted gene on mouse proximal chromosome 11, a candidate for the Silver-Russell syndrome gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Association of a redefined proximal mouse chromosome 11 imprinting region and U2afbp-rs/U2af1-rs1 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Interaction of a GRB-IR splice variant (a human GRB10 homolog) with the insulin and insulin-like growth factor I receptors. Evidence for a role in mitogenic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Interaction of the Grb10 adapter protein with the Raf1 and MEK1 kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Binding of SH2 containing proteins to the insulin receptor: a new way for modulating insulin signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

The Grb7 family proteins: structure, interactions with other signaling molecules and potential cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Sequence analysis identifies a ras-associating (RA)-like domain in the N-termini of band 4.1/JEF domains and in the Grb7/10/14 adapter family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Grb10 interacts differentially with the insulin receptor, insulin-like growth factor I receptor, and epidermal growth factor receptor via the Grb10 Src homology 2 (SH2) domain and a second novel domain located between the pleckstrin homology [...]

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Inhibition of hGrb10 binding to the insulin receptor by functional domain-mediated oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

C. elegans cell migration gene mig-10 shares similarities with a family of SH2 domain proteins and acts cell nonautonomously in excretory canal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Grb10, a positive, stimulatory signaling adapter in platelet-derived growth factor BB-, insulin-like growth factor I-, and insulin-mediated mitogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Structural basis for dimerization of the Grb10 Src homology 2 domain. Implications for ligand specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Localization of endogenous Grb10 to the mitochondria and its interaction with the mitochondrial-associated Raf-1 pool

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Identification of Grb10 as a direct substrate for members of the Src tyrosine kinase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

The adapter protein, Grb10, is a positive regulator of vascular endothelial growth factor signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Evidence for an interaction between the insulin receptor and Grb7. A role for two of its binding domains, PIR and SH2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Grb10 inhibits insulin-stimulated insulin receptor substrate (IRS)-phosphatidylinositol 3-kinase/Akt signaling pathway by disrupting the association of IRS-1/IRS-2 with the insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Association of the insulin receptor with phospholipase C-gamma (PLCgamma) in 3T3-L1 adipocytes suggests a role for PLCgamma in metabolic signaling by insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Molecular and cellular analysis of Grb2 SH3 domain mutants: interaction with Sos and dynamin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

In vivo protein transduction: delivery of a biologically active protein into the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Activation of mitogen-activated protein kinase and phosphatidylinositol 3'-kinase is not sufficient for the hormonal stimulation of glucose uptake, lipogenesis, or glycogen synthesis in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Regulation of System A amino acid transport in L6 rat skeletal muscle cells by insulin, chemical and hyperthermic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Inhibition of phosphatidylinositol 3-kinase activity by adenovirus-mediated gene transfer and its effect on insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Facilitative glucose transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Getting hydrophilic compounds into cells: lessons from homeopeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Protein transduction: unrestricted delivery into all cells?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Clinical review 125: The insulin receptor and its cellular targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Insulin stimulation of mitogen-activated protein kinase, p90rsk, and p70 S6 kinase in skeletal muscle of normal and insulin-resistant mice. Implications for the regulation of glycogen synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

CAP defines a second signalling pathway required for insulin-stimulated glucose transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

p38 mitogen-activated protein kinase phosphorylates cytosolic phospholipase A2 (cPLA2) in thrombin-stimulated platelets. Evidence that proline-directed phosphorylation is not required for mobilization of arachidonic acid by cPLA2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Molecular cloning and characterization of a novel p38 mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

The IRS-signalling system: a network of docking proteins that mediate insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

PSM, a mediator of PDGF-BB-, IGF-I-, and insulin-stimulated mitogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

The inability of phosphatidylinositol 3-kinase activation to stimulate GLUT4 translocation indicates additional signaling pathways are required for insulin-stimulated glucose uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

An inhibitor of p38 mitogen-activated protein kinase prevents insulin-stimulated glucose transport but not glucose transporter translocation in 3T3-L1 adipocytes and L6 myotubes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Regulation of glucose transport and glycogen synthesis in L6 muscle cells during oxidative stress. Evidence for cross-talk between the insulin and SAPK2/p38 mitogen-activated protein kinase signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

GLUT4 translocation precedes the stimulation of glucose uptake by insulin in muscle cells: potential activation of GLUT4 via p38 mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Oncogenes in Ras signalling pathway dictate host-cell permissiveness to herpes simplex virus 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

The BPS domain of Grb10 inhibits the catalytic activity of the insulin and IGF1 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

The role of mGrb10alpha in insulin-like growth factor I-mediated growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Identification of the rat adapter Grb14 as an inhibitor of insulin actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Inhibition of insulin receptor catalytic activity by the molecular adapter Grb14.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Specific inhibition by hGRB10zeta of insulin-induced glycogen synthase activation: evidence for a novel signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Role for the adaptor protein Grb10 in the activation of Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Imprinting regulation of the murine Meg1/Grb10 and human GRB10 genes; roles of brain-specific promoters and mouse-specific CTCF-binding sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Disruption of the imprinted Grb10 gene leads to disproportionate overgrowth by an Igf2-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

The Grb10/Nedd4 complex regulates ligand-induced ubiquitination and stability of the insulin-like growth factor I receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Two novel proteins that are linked to insulin-like growth factor (IGF-I) receptors by the Grb10 adapter and modulate IGF-I signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Regulation and functional roles of Grb14.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

Grb10 exceeding the boundaries of a common signaling adapter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

The Grb7 Family of Signalling Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304599200

21 January 2018

Identifiers

DOI

10.1074/JBC.M304599200

1 reference

22 September 2017

1 reference