Induction of phase 2 enzymes by serum oxidized polyamines through activation of Nrf2: effect of the polyamine metabolite acrolein (Q40645610)

22 September 2017

Induction of phase 2 enzymes by serum oxidized polyamines through activation of Nrf2: effect of the polyamine metabolite acrolein (English)

1 reference

22 September 2017

Mi-Kyoung Kwak

1

1 reference

PubMed ID

12763045

22 September 2017

Thomas W Kensler

series ordinal

2

1 reference

PubMed ID

12763045

22 September 2017

Robert A Casero

series ordinal

3

1 reference

22 September 2017

1 June 2003

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Biochemical and Biophysical Research Communications

22 September 2017

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22 September 2017

305

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22 September 2017

662-670

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22 September 2017

3

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22 September 2017

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Polyamines as targets for therapeutic intervention

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SOS induction of the recA gene by UV-, gamma-irradiation and mitomycin C is mediated by polyamines in Escherichia coli K-12

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Genomic identification and biochemical characterization of the mammalian polyamine oxidase involved in polyamine back-conversion

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Identification and characterization of a novel flavin-containing spermine oxidase of mammalian cell origin

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Reversal by aminoguanidine of the inhibition of proliferation of human fibroblasts by spermidine and spermine

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Polyamine cytotoxicity in the presence of bovine serum amine oxidase

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Diamine oxidase: an overview of historical, biochemical and functional aspects

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Diamine oxidase activity and biochemical markers in human seminal plasma

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Aldehyde dehydrogenase and cytotoxicity of purified bovine serum amine oxidase and spermine in Chinese hamster ovary cells

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The role of polyamine catabolism in polyamine analogue-induced programmed cell death

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Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene

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An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

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Functional antioxidant responsive elements.

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Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages

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Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

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Solid-phase extraction and determination of dansyl derivatives of unconjugated and acetylated polyamines by reversed-phase liquid chromatography: improved separation systems for polyamines in cerebrospinal fluid, urine and tissue

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Mouse glutathione S-transferase Ya subunit: gene structure and sequence

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Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene

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Role of polyamines in mediating malignant transformation and oncogene expression

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The identification of a cis-element and a trans-acting factor involved in the response to polyamines and polyamine analogues in the regulation of the human spermidine/spermine N1-acetyltransferase gene transcription

7 January 2021

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Cloning and characterization of human polyamine-modulated factor-1, a transcriptional cofactor that regulates the transcription of the spermidine/spermine N(1)-acetyltransferase gene

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Characterization of the interaction between the transcription factors human polyamine modulated factor (PMF-1) and NF-E2-related factor 2 (Nrf-2) in the transcriptional regulation of the spermidine/spermine N1-acetyltransferase (SSAT) gene

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Mechanisms of spermine toxicity in baby-hamster kidney (BHK) cells. The role of amine oxidases and oxidative stress

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Effects of MDL 72527, a specific inhibitor of polyamine oxidase, on brain edema, ischemic injury volume, and tissue polyamine levels in rats after temporary middle cerebral artery occlusion.

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Cerebral ischemia enhances polyamine oxidation: identification of enzymatically formed 3-aminopropanal as an endogenous mediator of neuronal and glial cell death

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A genetic model for colorectal tumorigenesis

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Nrf2 is essential for protection against acute pulmonary injury in mice

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An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen

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Linkage analysis of susceptibility to hyperoxia. Nrf2 is a candidate gene

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Role of phase 2 enzyme induction in chemoprotection by dithiolethiones

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Accelerated DNA adduct formation in the lung of the Nrf2 knockout mouse exposed to diesel exhaust

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Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

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Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene

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The molecular effects of acrolein

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Dependence of aldehyde dehydrogenase-mediated oxazaphosphorine resistance on soluble thiols: importance of thiol interactions with the secondary metabolite acrolein

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The role of acrolein in allyl alcohol-induced lipid peroxidation and liver cell damage in mice

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4-Hydroxy-2-nonenal increases gamma-glutamylcysteine synthetase gene expression in alveolar epithelial cells

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Cellular response to the redox active lipid peroxidation products: induction of glutathione S-transferase P by 4-hydroxy-2-nonenal

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Acrolein causes transcriptional induction of phase II genes by activation of Nrf2 in human lung type II epithelial (A549) cells

7 January 2021

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Polyamine oxidase, properties and functions

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-291X(03)00834-9

1 reference

22 September 2017

1 reference

PubMed ID

12763045