Determinants of Non-toxicity in the Gastric Pathogen Helicobacter pylori (Q40648996)

22 September 2017

Determinants of non-toxicity in the gastric pathogen Helicobacter pylori (English)

1 reference

22 September 2017

Determinants of Non-toxicity in the Gastric Pathogen Helicobacter pylori (English)

1 reference

https://api.crossref.org/works/10.1074/JBC.M304071200

31 December 2023

0 references

1 reference

https://api.crossref.org/works/10.1074/JBC.M304071200

31 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M304071200

31 December 2023

5

John C. Atherton

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12738773

31 December 2023

author name string

Brian Dove

4

1 reference

22 September 2017

Darren P. Letley

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12738773

31 December 2023

Joanne L. Rhead

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12738773

31 December 2023

Rachel J. Twells

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12738773

31 December 2023

language of work or name

English

0 references

publication date

8 May 2003

1 reference

full work available at URL

22 September 2017

http://www.jbc.org/article/S0021925820846298/pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12738773

https://api.elsevier.com/content/article/PII:S0021925820846298?httpAccept=text/xml

31 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M304071200

https://api.elsevier.com/content/article/PII:S0021925820846298?httpAccept=text/plain

31 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M304071200

https://syndication.highwire.org/content/doi/10.1074/jbc.M304071200

31 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M304071200

Journal of Biological Chemistry

31 December 2023

published in

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22 September 2017

278

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22 September 2017

29

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22 September 2017

26734-26741

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Helicobacter pylori infection and the risk of gastric carcinoma

22 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Helicobacter pylori infection and gastric lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Unidentified curved bacilli on gastric epithelium in active chronic gastritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

The interrelationship between cytotoxin-associated gene A, vacuolating cytotoxin, and Helicobacter pylori-related diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Clinical relevance of the Helicobacter pylori gene for blood-group antigen-binding adhesin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Cytotoxic activity in broth-culture filtrates of Campylobacter pylori

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Development of a mouse model of Helicobacter pylori infection that mimics human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Virulence factors of Helicobacter pylori responsible for gastric diseases in Mongolian gerbil

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Genetic analysis of the Helicobacter pylori vacuolating cytotoxin: structural similarities with the IgA protease type of exported protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Oligomeric and subunit structure of the Helicobacter pylori vacuolating cytotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

The m2 form of the Helicobacter pylori cytotoxin has cell type-specific vacuolating activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Expression and binding analysis of GST-VacA fusions reveals that the C-terminal approximately 100-residue segment of exotoxin is crucial for binding in HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Formation of anion-selective channels in the cell plasma membrane by the toxin VacA of Helicobacter pylori is required for its biological activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Vacuoles induced by Helicobacter pylori toxin contain both late endosomal and lysosomal markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Cellular vacuoles induced by Helicobacter pylori originate from late endosomal compartments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

The vacuolar ATPase proton pump is present on intracellular vacuoles induced by Helicobacter pylori.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Analysis of Helicobacter pylori vacA and cagA genotypes and serum antibody profile in benign and malignant gastroduodenal diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Natural diversity in the N terminus of the mature vacuolating cytotoxin of Helicobacter pylori determines cytotoxin activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

A 12-amino-acid segment, present in type s2 but not type s1 Helicobacter pylori VacA proteins, abolishes cytotoxin activity and alters membrane channel formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Cell specificity of Helicobacter pylori cytotoxin is determined by a short region in the polymorphic midregion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Characterization of the C-terminal domain of Helicobacter pylori vacuolating toxin and its relationship with extracellular toxin production

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Amino-terminal hydrophobic region of Helicobacter pylori vacuolating cytotoxin (VacA) mediates transmembrane protein dimerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Vacuolating cytotoxin of Helicobacter pylori induces apoptosis in the human gastric epithelial cell line AGS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Selective inhibition of Ii-dependent antigen presentation by Helicobacter pylori toxin VacA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

The VacA toxin of Helicobacter pylori identifies a new intermediate filament-interacting protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Vacuolating cytotoxin (vacA) alleles of Helicobacter pylori comprise two geographically widespread types, m1 and m2, and have evolved through limited recombination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Recombination and clonal groupings within Helicobacter pylori from different geographical regions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Free recombination within Helicobacter pylori

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Evolution of functional polymorphism in the gene coding for the Helicobacter pylori cytotoxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

The complete genome sequence of the gastric pathogen Helicobacter pylori

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Inhibition of the vacuolating and anion channel activities of the VacA toxin of Helicobacter pylori

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Mucosal IgA recognition of Helicobacter pylori 120 kDa protein, peptic ulceration, and gastric pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Identification of the minimal intracellular vacuolating domain of the Helicobacter pylori vacuolating toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Bafilomycin A1 inhibits Helicobacter pylori-induced vacuolization of HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Cell vacuolization induced by Helicobacter pylori: inhibition by bafilomycins A1, B1, C1 and D

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Helicobacter pylori vacuolating toxin accumulates within the endosomal-vacuolar compartment of cultured gastric cells and potentiates the vacuolating activity of ammonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Amino terminus and the first four membrane-spanning segments of the Arabidopsis K+ channel KAT1 confer inward-rectification property of plant-animal chimeric channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Clinical and pathological importance of heterogeneity in vacA, the vacuolating cytotoxin gene of Helicobacter pylori

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

A dominant negative mutant of Helicobacter pylori vacuolating toxin (VacA) inhibits VacA-induced cell vacuolation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Molecular Methods for Detecting Ulcerogenic Strains of H. pylori

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Iron acquisition and virulence in Helicobacter pylori: a major role for FeoB, a high-affinity ferrous iron transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

The Helicobacter pylori vacA s1, m1 genotype and cagA is associated with gastric carcinoma in Germany

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304071200

Cytotoxin production by Campylobacter pylori strains isolated from patients with peptic ulcers and from patients with chronic gastritis only

21 January 2018

4

1 reference

https://api.crossref.org/works/10.1074/JBC.M304071200

Characterization of and human serologic response to proteins in Helicobacter pylori broth culture supernatants with vacuolizing cytotoxin activity

31 December 2023

6

1 reference

https://api.crossref.org/works/10.1074/JBC.M304071200

Pathological significance and molecular characterization of the vacuolating toxin gene of Helicobacter pylori

31 December 2023

16

1 reference

https://api.crossref.org/works/10.1074/JBC.M304071200

Allelic diversity of the Helicobacter pylori vacuolating cytotoxin gene in South Africa: rarity of the vacA s1a genotype and natural occurrence of an s2/m1 allele

31 December 2023

32

1 reference

https://api.crossref.org/works/10.1074/JBC.M304071200

Typing of Helicobacter pylori vacA gene and detection of cagA gene by PCR and reverse hybridization

31 December 2023

34

1 reference

https://api.crossref.org/works/10.1074/JBC.M304071200

Identification and analysis of a new vacA genotype variant of Helicobacter pylori in different patient groups in Germany

31 December 2023

35

1 reference

https://api.crossref.org/works/10.1074/JBC.M304071200

Diversity of Helicobacter pylori vacA and cagA genes and relationship to VacA and CagA protein expression, cytotoxin production, and associated diseases.

31 December 2023

36

1 reference

https://api.crossref.org/works/10.1074/JBC.M304071200

Identification of the Helicobacter pylori VacA toxin domain active in the cell cytosol

31 December 2023

40

1 reference

https://api.crossref.org/works/10.1074/JBC.M304071200

Simple and accurate PCR-based system for typing vacuolating cytotoxin alleles of Helicobacter pylori

31 December 2023

46

1 reference

https://api.crossref.org/works/10.1074/JBC.M304071200

Colonization of Mexican patients by multiple Helicobacter pylori strains with different vacA and cagA genotypes.

31 December 2023

55

1 reference

https://api.crossref.org/works/10.1074/JBC.M304071200

Conservation and diversity of Campylobacter pyloridis major antigens.

31 December 2023

64

1 reference

https://api.crossref.org/works/10.1074/JBC.M304071200

31 December 2023

Identifiers

1 reference

22 September 2017

1 reference