RAD51 is involved in repair of damage associated with DNA replication in mammalian cells (Q40653432)

22 September 2017

RAD51 is involved in repair of damage associated with DNA replication in mammalian cells (English)

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22 September 2017

6

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22 September 2017

Cecilia Lundin

1

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22 September 2017

Niklas Schultz

2

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22 September 2017

Catherine Arnaudeau

3

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22 September 2017

Atul Mohindra

4

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22 September 2017

Lasse Tengbjerg Hansen

5

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22 September 2017

language of work or name

English

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publication date

1 May 2003

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Journal of Molecular Biology

22 September 2017

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22 September 2017

328

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22 September 2017

521-535

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22 September 2017

3

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Genome maintenance mechanisms for preventing cancer

22 September 2017

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Chromosomal stability and the DNA double-stranded break connection

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Role of the human RAD51 protein in homologous recombination and double-stranded-break repair.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Targeted disruption of the Rad51 gene leads to lethality in embryonic mice

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Rescue of arrested replication forks by homologous recombination

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Characterization of homologous recombination induced by replication inhibition in mammalian cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Different roles for nonhomologous end joining and homologous recombination following replication arrest in mammalian cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Elevated recombination in immortal human cells is mediated by HsRAD51 recombinase

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

p53 splice acceptor site mutation and increased HsRAD51 protein expression in Bloom's syndrome GM1492 fibroblasts

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Increase of spontaneous intrachromosomal homologous recombination in mammalian cells expressing a mutant p53 protein

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Inactivation of p53 results in high rates of homologous recombination

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

A transactivation-deficient mouse model provides insights into Trp53 regulation and function

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Functional proteomics of transforming growth factor-beta1-stimulated Mv1Lu epithelial cells: Rad51 as a target of TGFbeta1-dependent regulation of DNA repair

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Association of BRCA1 with Rad51 in mitotic and meiotic cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Brca2 is required for embryonic cellular proliferation in the mouse

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Involvement of Brca2 in DNA repair

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Role of BRCA2 in control of the RAD51 recombination and DNA repair protein.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Expression of BRC repeats in breast cancer cells disrupts the BRCA2-Rad51 complex and leads to radiation hypersensitivity and loss of G(2)/M checkpoint control

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Brca2 (XRCC11) deficiency results in radioresistant DNA synthesis and a higher frequency of spontaneous deletions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

BRCA2 is required for homology-directed repair of chromosomal breaks

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Deficiency in BRCA2 leads to increase in non-conservative homologous recombination.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Cancer susceptibility and the functions of BRCA1 and BRCA2

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Identification of Rad51 alteration in patients with bilateral breast cancer

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Detection of loss of heterozygosity at RAD51, RAD52, RAD54 and BRCA1 and BRCA2 loci in breast cancer: pathological correlations.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

DNA repair and recombination factor Rad51 is over-expressed in human pancreatic adenocarcinoma

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

The RAD51 protein supports homologous recombination by an exchange mechanism in mammalian cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Gene targeting is enhanced in human cells overexpressing hRAD51.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Characterization of mammalian RAD51 double strand break repair using non-lethal dominant-negative forms.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Overexpression of human RAD51 and RAD52 reduces double-strand break-induced homologous recombination in mammalian cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Role for caspase-mediated cleavage of Rad51 in induction of apoptosis by DNA damage

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

A partial hprt gene duplication generated by non-homologous recombination in V79 Chinese hamster cells is eliminated by homologous recombination

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Reduction of Ribonucleotides

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

International Commission for Protection Against Environmental Mutagens and Carcinogens. Mutagenicity and carcinogenicity of topoisomerase-interactive agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Eucaryotic DNA: organization of the genome for replication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Localization to chromosome 7q36.1 of the human XRCC2 gene, determining sensitivity to DNA-damaging agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

The isolation and genetic analysis of V79-derived etoposide sensitive Chinese hamster cell mutants: two new complementation groups of etoposide sensitive mutants.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Effects of HsRad51 overexpression on cell proliferation, cell cycle progression, and apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Inhibition of DNA synthesis is a potent mechanism by which cytostatic drugs induce homologous recombination in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Circular DNA of 3T6R50 double minute chromosomes

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Estimation of circular DNA size using gamma-irradiation and pulsed-field gel electrophoresis

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Measurement of DNA Double-strand Breaks in CHO Cells at Various Stages of the Cell Cycle Using Pulsed Field Gel Electrophoresis: Calibration by Means of125I Decay

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Topoisomerase II can unlink replicating DNA by precatenane removal

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

BCR/ABL regulates mammalian RecA homologs, resulting in drug resistance

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

A model for replication repair in mammalian cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Positive torsional strain causes the formation of a four-way junction at replication forks

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Holliday junctions accumulate in replication mutants via a RecA homolog-independent mechanism

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

Characterization of mutants involving partial exon duplications in the hprt gene of Chinese hamster V79 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

XRCC3 is required for efficient repair of chromosome breaks by homologous recombination

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900313-9

10.1016/S0022-2836(03)00313-9

7 January 2021

Identifiers

DOI

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22 September 2017

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