Hepatitis B virus X protein induces cell death by causing loss of mitochondrial membrane potential (Q40658238)

22 September 2017

Hepatitis B virus X protein induces cell death by causing loss of mitochondrial membrane potential (English)

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22 September 2017

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Yumiko Shirakata

1

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PubMed ID

12676947

22 September 2017

Katsuro Koike

series ordinal

2

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PubMed ID

12676947

22 September 2017

language of work or name

English

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publication date

3 April 2003

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Journal of Biological Chemistry

22 September 2017

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22 September 2017

278

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22 September 2017

24

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22 September 2017

22071-22078

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Association of hepatitis B virus X protein with mitochondria causes mitochondrial aggregation at the nuclear periphery, leading to cell death

22 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

Hepatitis B virus X protein colocalizes to mitochondria with a human voltage-dependent anion channel, HVDAC3, and alters its transmembrane potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

The X gene of hepatitis B virus induced growth stimulation and tumorigenic transformation of mouse NIH3T3 cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M301606200

HBx gene of hepatitis B virus induces liver cancer in transgenic mice

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M301606200

Increased sensitivity to the hepatocarcinogen diethylnitrosamine in transgenic mice carrying the hepatitis B virus X gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

Hepatitis B virus X protein acts as a tumor promoter in development of diethylnitrosamine-induced preneoplastic lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

Calcium signaling by HBx protein in hepatitis B virus DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

Hepatitis B virus X gene can transactivate heterologous viral sequences

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M301606200

Hepatitis B virus transactivator HBx uses a tumour promoter signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

The hepatitis B virus transactivator HBx causes elevation of diacylglycerol and activation of protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

Hepatitis B virus HBx protein activates Ras-GTP complex formation and establishes a Ras, Raf, MAP kinase signaling cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

HBx protein of hepatitis B virus activates Jak1-STAT signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-kappa B via oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

Hepadnaviral X Protein:Review of Recent Progress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

HBV X protein alters the DNA binding specificity of CREB and ATF-2 by protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

Hepatitis B virus X protein is a transcriptional modulator that communicates with transcription factor IIB and the RNA polymerase II subunit 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

Hepatitis B virus pX interacts with HBXAP, a PHD finger protein to coactivate transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

Hepatitis B virus HBx protein sensitizes cells to apoptotic killing by tumor necrosis factor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

The proapoptotic effect of hepatitis B virus HBx protein correlates with its transactivation activity in stably transfected cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

Mitochondria and apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M301606200

Mitochondrial control of cell death

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M301606200

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M301606200

Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

Calcium induced release of mitochondrial cytochrome c by different mechanisms selective for brain versus liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

Mitochondrial membrane potential monitored by JC-1 dye.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

JC-1, but not DiOC6(3) or rhodamine 123, is a reliable fluorescent probe to assess delta psi changes in intact cells: implications for studies on mitochondrial functionality during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

Hepatitis B virus X mutants, present in hepatocellular carcinoma tissue abrogate both the antiproliferative and transactivation effects of HBx.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

Induction of apoptosis by the transactivating domains of the hepatitis B virus X gene leads to suppression of oncogenic transformation of primary rat embryo fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

Apoptotic and antiapoptotic mechanisms in stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

Mitochondria and degenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

Apoptosis: a link between cancer genetics and chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

Potential roles of apoptosis in viral pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

21 January 2018

Viruses and Apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

Apoptosis: programmed cell death in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

A matter of life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301606200

21 January 2018

Identifiers

DOI

10.1074/JBC.M301606200

1 reference

22 September 2017

1 reference

PubMed ID

12676947