Gliclazide protects pancreatic beta-cells from damage by hydrogen peroxide (Q40662814)

22 September 2017

Gliclazide protects pancreatic beta-cells from damage by hydrogen peroxide (English)

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22 September 2017

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Kiyoko Kimoto

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22 September 2017

Kenji Suzuki

2

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22 September 2017

Takako Kizaki

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22 September 2017

Yoshiaki Hitomi

4

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22 September 2017

Hitoshi Ishida

5

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22 September 2017

Hidenori Katsuta

6

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22 September 2017

Eisuke Itoh

7

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22 September 2017

Tomomi Ookawara

8

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22 September 2017

Keiichiro Suzuki

9

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22 September 2017

Koichi Honke

10

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22 September 2017

Hideki Ohno

11

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22 September 2017

1 March 2003

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Biochemical and Biophysical Research Communications

22 September 2017

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22 September 2017

303

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22 September 2017

1

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22 September 2017

112-119

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Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues.

22 September 2017

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Reducing sugars trigger oxidative modification and apoptosis in pancreatic beta-cells by provoking oxidative stress through the glycation reaction

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Glycation-dependent, reactive oxygen species-mediated suppression of the insulin gene promoter activity in HIT cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Prevention of glucose toxicity in HIT-T15 cells and Zucker diabetic fatty rats by antioxidants

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Beneficial effects of antioxidants in diabetes: possible protection of pancreatic beta-cells against glucose toxicity

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Effects of gliclazide on platelet reactivity and free radicals in type II diabetic patients: Clinical assessment

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Gliclazide decreases cell-mediated low-density lipoprotein (LDL) oxidation and reduces monocyte adhesion to endothelial cells induced by oxidatively modified LDL

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Free radical scavenging activity of sulfonylureas: a clinical assessment of the effect of gliclazide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

New biomarker evidence of oxidative DNA damage in patients with non-insulin-dependent diabetes mellitus.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

The beta cell in autoimmune diabetes: many mechanisms and pathways of loss

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Banting lecture 1990. Beta-cells in type II diabetes mellitus

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Pathogenesis of NIDDM. A balanced overview

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Oxidative damage to DNA in diabetes mellitus

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Preservation of insulin mRNA levels and insulin secretion in HIT cells by avoidance of chronic exposure to high glucose concentrations

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Chronic exposure of HIT cells to high glucose concentrations paradoxically decreases insulin gene transcription and alters binding of insulin gene regulatory protein.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Chronic exposure of betaTC-6 cells to supraphysiologic concentrations of glucose decreases binding of the RIPE3b1 insulin gene transcription activator

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Effects of gliclazide versus metformin on the clinical profile and lipid peroxidation markers in type 2 diabetes

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

In vitro and in vivo antioxidant properties of gliclazide.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Increased expression of antioxidant and antiapoptotic genes in islets that may contribute to beta-cell survival during chronic hyperglycemia

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Heme oxygenase-1 protects pancreatic beta cells from apoptosis caused by various stimuli

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Gliclazide: a general free radical scavenger

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

The Bcl-2 protein family: arbiters of cell survival

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Altered bcl-2 and bax expression and intracellular Ca2+ signaling in apoptosis of pancreatic cells and the impairment of glucose-induced insulin secretion

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Increased p21CIP1/WAF1and B Cell Lymphoma Leukemia-xLExpression and Reduced Apoptosis in Alveolar Macrophages from Smokers

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

A20 inhibits cytokine-induced apoptosis and nuclear factor kappaB-dependent gene activation in islets

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Dose-dependent cysteine-mediated protection of insulin-producing cells from damage by hydrogen peroxide

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

PKC-Dependent Stimulation of Exocytosis by Sulfonylureas in Pancreatic beta Cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Direct effects of tolbutamide on mitochondrial function, intracellular Ca2+ and exocytosis in pancreatic beta-cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Sulfonylurea-mediated stimulation of insulin exocytosis via an ATP-sensitive K+ channel-independent action

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

Glucose and tolbutamide induce apoptosis in pancreatic beta-cells. A process dependent on intracellular Ca2+ concentration

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900310-3

10.1016/S0006-291X(03)00310-3

7 January 2021

Identifiers

DOI

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22 September 2017

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