VCP746, a novel A1 adenosine receptor biased agonist, reduces hypertrophy in a rat neonatal cardiac myocyte model. (Q40667527)

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17 March 2020

title

VCP746, a novel A1 adenosine receptor biased agonist, reduces hypertrophy in a rat neonatal cardiac myocyte model (English)

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17 March 2020

2

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17 March 2020

Peter J. Scammells

3

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17 March 2020

Arthur Christopoulos

5

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17 March 2020

author name string

Chung H Chuo

1

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17 March 2020

Lauren T May

6

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17 March 2020

Paul J White

7

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Bing H Wang

8

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17 March 2020

Henry Krum

4

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17 March 2020

publication date

1 October 2016

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Clinical and Experimental Pharmacology and Physiology

17 March 2020

published in

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volume

43

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issue

10

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17 March 2020

page(s)

976-982

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Incidence and prevalence of heart failure in elderly persons, 1994-2003.

17 March 2020

cites work

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Inhibition of phenylephrine-induced cardiomyocyte hypertrophy by activation of multiple adenosine receptor subtypes

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Heart failure therapy at a crossroad: are there limits to the neurohormonal model?

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Increased interleukin-1β levels are associated with left ventricular hypertrophy and remodelling following acute ST segment elevation myocardial infarction treated by primary percutaneous coronary intervention

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Cytokine gene expression after myocardial infarction in rat hearts: possible implication in left ventricular remodeling

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Adenosine receptor-mediated cardioprotection: are all 4 subtypes required or redundant?

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Cardiac myocyte-secreted cAMP exerts paracrine action via adenosine receptor activation.

21 January 2018

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Activation of adenosine A1 receptor attenuates cardiac hypertrophy and prevents heart failure in murine left ventricular pressure-overload model

21 January 2018

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Separation of on-target efficacy from adverse effects through rational design of a bitopic adenosine receptor agonist

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Inositol polyphosphate 1-phosphatase is a novel antihypertrophic factor

21 January 2018

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Adenoviral-directed expression of the type 1A angiotensin receptor promotes cardiomyocyte hypertrophy via transactivation of the epidermal growth factor receptor

21 January 2018

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Return to the fetal gene program: a suggested metabolic link to gene expression in the heart

21 January 2018

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Atrial natriuretic peptide distribution in fetal and failed adult human hearts.

21 January 2018

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Inhibitory regulation of hypertrophy by endogenous atrial natriuretic peptide in cultured cardiac myocytes

21 January 2018

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Myofibrillar remodeling in cardiac hypertrophy, heart failure and cardiomyopathies

21 January 2018

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Impact of beta-myosin heavy chain expression on cardiac function during stress

21 January 2018

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Heme oxygenase-1 inhibits angiotensin II-induced cardiac hypertrophy in vitro and in vivo

21 January 2018

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Extracellular Signal-regulated Kinase Plays an Essential Role in Hypertrophic Agonists, Endothelin-1 and Phenylephrine-induced Cardiomyocyte Hypertrophy

21 January 2018

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α-Actin isoform distribution in normal and failing human heart: a morphological, morphometric, and biochemical study

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/1440-1681.12616

1 reference

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17 March 2020

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