Role of the connecting peptide in insulin biosynthesis (Q40670213)

22 September 2017

Role of the connecting peptide in insulin biosynthesis (English)

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22 September 2017

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Ming Liu

1

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22 September 2017

Jose Ramos-Castañeda

series ordinal

2

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22 September 2017

Peter Arvan

series ordinal

3

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22 September 2017

language of work or name

English

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publication date

14 February 2003

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Journal of Biological Chemistry

22 September 2017

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22 September 2017

278

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22 September 2017

17

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22 September 2017

14798-14805

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The insulin A and B chains contain structural information for the formation of the native molecule. Studies with protein disulphide-isomerase

22 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

Mechanism of insulin chain combination. Asymmetric roles of A-chain alpha-helices in disulfide pairing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

Mini-proinsulin and mini-IGF-I: homologous protein sequences encoding non-homologous structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

The proprotein convertases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

Efficient targeting to storage granules of human proinsulins with altered propeptide domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

Remission in models of type 1 diabetes by gene therapy using a single-chain insulin analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

Behavior in the eukaryotic secretory pathway of insulin-containing fusion proteins and single-chain insulins bearing various B-chain mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

Formation, isomerisation and reduction of disulphide bonds during protein quality control in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

Formation and transfer of disulphide bonds in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

Structure of a protein in a kinetic trap

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

The different energetic state of the intra A-chain/domain disulfide of insulin and insulin-like growth factor 1 is mainly controlled by their B-chain/domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

The different folding behavior of insulin and insulin-like growth factor 1 is mainly controlled by their B-chain/domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

Intracellular transport of proinsulin in pancreatic beta-cells. Structural maturation probed by disulfide accessibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

Putative disulfide-forming pathway of porcine insulin precursor during its refolding in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

Reexamination of the folding of BPTI: predominance of native intermediates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

Protein folding during cotranslational translocation in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

ERp44, a novel endoplasmic reticulum folding assistant of the thioredoxin family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

The luminal domain of ATF6 senses endoplasmic reticulum (ER) stress and causes translocation of ATF6 from the ER to the Golgi

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

Distinct roles of activating transcription factor 6 (ATF6) and double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) in transcription during the mammalian unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

Catalytic activity and chaperone function of human protein-disulfide isomerase are required for the efficient refolding of proinsulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

Secretory pathway quality control operating in Golgi, plasmalemmal, and endosomal systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

Effects of cysteine to serine substitutions in the two inter-chain disulfide bonds of insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

Prediction of tight turns and their types in proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

A mutation in the insulin 2 gene induces diabetes with severe pancreatic beta-cell dysfunction in the Mody mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212070200

21 January 2018

Identifiers

DOI

10.1074/JBC.M212070200

1 reference

22 September 2017

1 reference