RNase L mediates transient control of the interferon response through modulation of the double-stranded RNA-dependent protein kinase PKR. (Q40671154)

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18 December 2019

title

RNase L mediates transient control of the interferon response through modulation of the double-stranded RNA-dependent protein kinase PKR (English)

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18 December 2019

1

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18 December 2019

Bryan Williams

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18 December 2019

13

Robert H Silverman

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18 December 2019

10

Mohammed N Al-Ahdal

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18 December 2019

author name string

Yunus M Siddiqui

2

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18 December 2019

Fahad al-Zoghaibi

3

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18 December 2019

Latifa al-Haj

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18 December 2019

Mohammed Dhalla

5

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18 December 2019

Aimin Zhou

6

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18 December 2019

Beihua Dong

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18 December 2019

Mark Whitmore

8

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18 December 2019

Jayashree Paranjape

9

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18 December 2019

Futwan Al-Mohanna

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18 December 2019

language of work or name

English

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publication date

11 February 2003

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Journal of Biological Chemistry

18 December 2019

number of pages

9

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based on heuristic

inferred from page(s)

published in

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18 December 2019

volume

278

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18 December 2019

issue

22

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18 December 2019

page(s)

20124-20132

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ARED: human AU-rich element-containing mRNA database reveals an unexpectedly diverse functional repertoire of encoded proteins

18 December 2019

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Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

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pppA2'p5'A2'p5'A: an inhibitor of protein synthesis synthesized with an enzyme fraction from interferon-treated cells

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Ribosomal RNA cleavage, nuclease activation and 2-5A (ppp(A2′p)nA) in interferon-treated cells

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Interferon action and apoptosis are defective in mice devoid of 2',5'-oligoadenylate-dependent RNase L

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Antiviral effects of recombinant tumour necrosis factor in vitro

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The alpha chemokine, interleukin 8, inhibits the antiviral action of interferon alpha

21 January 2018

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Effect of deficiency of the double-stranded RNA-dependent protein kinase, PKR, on antiviral resistance in the presence or absence of ribonuclease L: HSV-1 replication is particularly sensitive to deficiency of the major IFN-mediated enzymes.

21 January 2018

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Internal initiation of translation directed by the 5'-untranslated region of the mRNA for eIF4G, a factor involved in the picornavirus-induced switch from cap-dependent to internal initiation

21 January 2018

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Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus.

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Rapid decrease in the levels of the double-stranded RNA-dependent protein kinase during virus infections

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Electron microscopy of chromatin

21 January 2018

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mRNA decay mediated by two distinct AU-rich elements from c-fos and granulocyte-macrophage colony-stimulating factor transcripts: different deadenylation kinetics and uncoupling from translation

21 January 2018

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Interferon action in triply deficient mice reveals the existence of alternative antiviral pathways.

21 January 2018

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Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection

21 January 2018

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Involvement of the double-stranded-RNA-dependent kinase PKR in interferon expression and interferon-mediated antiviral activity

21 January 2018

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PACT, a stress-modulated cellular activator of interferon-induced double-stranded RNA-activated protein kinase, PKR.

21 January 2018

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A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis

21 January 2018

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Analysis and origins of the human and mouse RNase L genes: mediators of interferon action

21 January 2018

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Synthesis and purification of single-stranded RNA for use in experiments with PKR and in cell-free translation systems.

21 January 2018

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Double-stranded poliovirus RNA inhibits initiation of protein synthesis by reticulocyte lysates

21 January 2018

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Reversal of the double-stranded-RNA-induced inhibition of protein synthesis by a catalytically inactive mutant of the protein kinase PKR.

21 January 2018

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The interferon-inducible double-stranded RNA-activated protein kinase self-associates in vitro and in vivo

21 January 2018

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

21 January 2018

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Activation of 2'-5' oligoadenylate synthetase by single-stranded and double-stranded RNA aptamers

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The 2-5A/RNase L/RNase L inhibitor (RLI) [correction of (RNI)] pathway regulates mitochondrial mRNAs stability in interferon alpha-treated H9 cells

21 January 2018

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Translational control perks up

21 January 2018

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Antiviral activity of a novel recombinant human interferon-alpha B/D hybrid

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M208766200

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18 December 2019

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