Mutations of Arg440 and Gly455/Gly456 oppositely change pH sensing of Na+/H+ exchanger 1. (Q40673458)

22 September 2017

title

Mutations of Arg440 and Gly455/Gly456 oppositely change pH sensing of Na+/H+ exchanger 1. (English)

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22 September 2017

Shigeo Wakabayashi

1

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22 September 2017

Takashi Hisamitsu

series ordinal

2

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22 September 2017

Tianxiang Pang

series ordinal

3

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22 September 2017

Munekazu Shigekawa

series ordinal

4

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22 September 2017

language of work or name

English

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publication date

30 January 2003

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Journal of Biological Chemistry

22 September 2017

number of pages

8

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based on heuristic

inferred from page(s)

published in

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22 September 2017

volume

278

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22 September 2017

issue

14

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22 September 2017

page(s)

11828-11835

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Na+/H+ exchangers of mammalian cells.

22 September 2017

cites work

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Na+/H+ exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferation

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A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchange

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Calcineurin homologous protein as an essential cofactor for Na+/H+ exchangers

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G alpha 13 stimulates Na+-H+ exchange through distinct Cdc42-dependent and RhoA-dependent pathways

21 January 2018

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The p42/p44 mitogen-activated protein kinase cascade is determinant in mediating activation of the Na+/H+ exchanger (NHE1 isoform) in response to growth factors

21 January 2018

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14-3-3 Binding to Na+/H+ exchanger isoform-1 is associated with serum-dependent activation of Na+/H+ exchange

21 January 2018

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The Nck-interacting kinase (NIK) phosphorylates the Na+-H+ exchanger NHE1 and regulates NHE1 activation by platelet-derived growth factor

21 January 2018

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Intracellular pH regulation by Na(+)/H(+) exchange requires phosphatidylinositol 4,5-bisphosphate.

21 January 2018

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The Na+/H+ antiporter cytoplasmic domain mediates growth factor signals and controls "H(+)-sensing"

21 January 2018

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Identification of cytoplasmic subdomains that control pH-sensing of the Na+/H+ exchanger (NHE1): pH-maintenance, ATP-sensitive, and flexible loop domains

21 January 2018

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A novel topology model of the human Na(+)/H(+) exchanger isoform 1

21 January 2018

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NHE6 protein possesses a signal peptide destined for endoplasmic reticulum membrane and localizes in secretory organelles of the cell

21 January 2018

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Second mutations rescue point mutant of the Na(+)/H(+) exchanger NHE1 showing defective surface expression

21 January 2018

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A specific mutation abolishing Na+/H+ antiport activity in hamster fibroblasts precludes growth at neutral and acidic pH

21 January 2018

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The Na+/H+ exchanger NHE-1 possesses N- and O-linked glycosylation restricted to the first N-terminal extracellular domain

21 January 2018

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Chimeric Na+/H+ exchangers: an epithelial membrane-bound N-terminal domain requires an epithelial cytoplasmic C-terminal domain for regulation by protein kinases

21 January 2018

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The open pore conformation of potassium channels

21 January 2018

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Structural changes in the calcium pump accompanying the dissociation of calcium

21 January 2018

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21 January 2018

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A point mutation of the Na+/H+ exchanger gene (NHE1) and amplification of the mutated allele confer amiloride resistance upon chronic acidosis

21 January 2018

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Identification of sites in the second exomembrane loop and ninth transmembrane helix of the mammalian Na+/H+ exchanger important for drug recognition and cation translocation.

21 January 2018

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Identification and characterization of functional residues in a Na+/H+ antiporter (NhaA) from Escherichia coli by random mutagenesis.

21 January 2018

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Three aspartic residues in membrane-spanning regions of Na+/H+ antiporter from Vibrio alginolyticus play a role in the activity of the carrier.

21 January 2018

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The nature of the accessible and buried surfaces in proteins

21 January 2018

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Protein volume in solution

21 January 2018

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Modifier role of internal H+ in activating the Na+–H+ exchanger in renal microvillus membrane vesicles

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M213243200

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22 September 2017

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