Aplidine, a new anticancer agent of marine origin, inhibits vascular endothelial growth factor (VEGF) secretion and blocks VEGF-VEGFR-1 (flt-1) autocrine loop in human leukemia cells MOLT-4. (Q40677359)

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scientific article published on January 2003

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English	Aplidine, a new anticancer agent of marine origin, inhibits vascular endothelial growth factor (VEGF) secretion and blocks VEGF-VEGFR-1 (flt-1) autocrine loop in human leukemia cells MOLT-4.	scientific article published on January 2003

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scholarly article

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16 December 2019

Aplidine, a new anticancer agent of marine origin, inhibits vascular endothelial growth factor (VEGF) secretion and blocks VEGF-VEGFR-1 (flt-1) autocrine loop in human leukemia cells MOLT-4 (English)

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16 December 2019

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Raffaella Giavazzi

10

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16 December 2019

Massimo Broggini

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16 December 2019

Sergio Marchini

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16 December 2019

Giulia Taraboletti

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16 December 2019

Maurizio D'Incalci

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16 December 2019

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Galliera E

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16 December 2019

Borsotti P

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16 December 2019

Erba E

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Sironi M

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16 December 2019

Jimeno J

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16 December 2019

Faircloth GT

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16 December 2019

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1 January 2003

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16 December 2019

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16 December 2019

52-59

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16 December 2019

1

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16 December 2019

https://scigraph.springernature.com/pub.10.1038/sj.leu.2402788

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In vitro activity of aplidine, a new marine-derived anti-cancer compound, on freshly explanted clonogenic human tumour cells and haematopoietic precursor cells

1 reference

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21 January 2018

Cytotoxicity and neurocytotoxicity of new marine anticancer agents evaluated using in vitro assays

1 reference

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Cell cycle phase perturbations and apoptosis in tumour cells induced by aplidine

1 reference

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21 January 2018

Vascular permeability factor/vascular endothelial growth factor inhibits anchorage-disruption-induced apoptosis in microvessel endothelial cells by inducing scaffold formation.

1 reference

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Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) delays and induces escape from senescence in human dermal microvascular endothelial cells.

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21 January 2018

Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells

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Expression of vascular endothelial growth factor and its receptors flt and KDR in ovarian carcinoma.

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Expression of vascular endothelial growth factor receptors in human prostate cancer

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Expression of vascular endothelial growth factor (VEGF) and VEGF receptors in human neuroblastomas

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Production of VEGF and expression of the VEGF receptors Flt-1 and KDR in primary cultures of epithelial and stromal cells derived from breast tumours

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21 January 2018

VEGF: an update on biological and therapeutic aspects

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Vascular endothelial growth factor is an autocrine growth factor in human malignant mesothelioma

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Vascular endothelial cell growth factor is an autocrine promoter of abnormal localized immature myeloid precursors and leukemia progenitor formation in myelodysplastic syndromes.

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Inhibition of both paracrine and autocrine VEGF/ VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias

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De novo expression of vascular endothelial growth factor in human pancreatic cancer: evidence for an autocrine mitogenic loop.

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21 January 2018

Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation

1 reference

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21 January 2018

Vascular endothelial growth factor (VEGF) upregulates BCL-2 and inhibits apoptosis in human and murine mammary adenocarcinoma cells

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p73 competes with p53 and attenuates its response in a human ovarian cancer cell line.

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Angiogenesis in cancer and other diseases

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Angiogenesis in acute promyelocytic leukemia: induction by vascular endothelial growth factor and inhibition by all-trans retinoic acid

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Antiproliferative effect of dehydrodidemnin B (DDB), a depsipeptide isolated from Mediterranean tunicates

1 reference

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7 January 2021

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Increased bone marrow vascularization in patients with acute myeloid leukaemia: a possible role for vascular endothelial growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402788

7 January 2021

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Angiogenesis in B-chronic lymphocytic leukemia

1 reference

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7 January 2021

based on heuristic

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Angiogenesis is increased in B-cell chronic lymphocytic leukemia

1 reference

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7 January 2021

based on heuristic

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Identifiers

10.1038/SJ.LEU.2402788

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16 December 2019

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16 December 2019

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