Transglutaminase cross-links in intranuclear inclusions in Huntington disease (Q40677519)

22 September 2017

Transglutaminase cross-links in intranuclear inclusions in Huntington disease (English)

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22 September 2017

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4

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22 September 2017

2

Christopher A Ross

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22 September 2017

Gina M Zainelli

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PubMed ID

12528814

22 September 2017

Juan C Troncoso

series ordinal

3

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22 September 2017

1 January 2003

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Journal of Neuropathology & Experimental Neurology

22 September 2017

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22 September 2017

62

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22 September 2017

1

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22 September 2017

14-24

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Intranuclear neuronal inclusions in Huntington's disease and dentatorubral and pallidoluysian atrophy: correlation between the density of inclusions and IT15 CAG triplet repeat length

22 September 2017

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https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Neuronal distribution of intranuclear inclusions in Huntington's disease with adult onset.

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Huntington's disease intranuclear inclusions contain truncated, ubiquitinated huntingtin protein

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

The length of polyglutamine tract, its level of expression, the rate of degradation, and the transglutaminase activity influence the formation of intracellular aggregates

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Pathogenesis of inclusion bodies in (CAG)n/Qn-expansion diseases with special reference to the role of tissue transglutaminase and to selective vulnerability

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Transglutaminase-catalyzed matrix cross-linking in differentiating cartilage: identification of osteonectin as a major glutaminyl substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Immunohistochemical detection of coagulation factor XIIIa in postmortem human brain tissue.

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Differential expression of multiple transglutaminases in human brain. Increased expression and cross-linking by transglutaminases 1 and 2 in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Transglutaminase aggregates huntingtin into nonamyloidogenic polymers, and its enzymatic activity increases in Huntington's disease brain nuclei

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Transglutaminase action imitates Huntington's disease: selective polymerization of Huntingtin containing expanded polyglutamine.

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Transglutaminase activity is related to CAG repeat length in patients with Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Tissue transglutaminase-catalyzed formation of high-molecular-weight aggregates in vitro is favored with long polyglutamine domains: a possible mechanism contributing to CAG-triplet diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Length of huntingtin and its polyglutamine tract influences localization and frequency of intracellular aggregates

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Transglutaminase activity and Nε(γ-glutamyl) lysine isopeptide levels during cell growth: An enzymic and immunological study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Elevated transglutaminase-induced bonds in PHF tau in Alzheimer's disease.

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Evidence for a role for transglutaminase in Huntington's disease and the potential therapeutic implications

21 January 2018

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https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Does tissue transglutaminase play a role in Huntington's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

N(epsilon)-(gamma-L-glutamyl)-L-lysine (GGEL) is increased in cerebrospinal fluid of patients with Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Alpha-synuclein immunoreactivity of huntingtin polyglutamine aggregates in striatum and cortex of Huntington's disease patients and transgenic mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

GTP-dependent conformational changes associated with the functional switch between Galpha and cross-linking activities in brain-derived tissue transglutaminase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Cross linking of polyglutamine domains catalyzed by tissue transglutaminase is greatly favored with pathological-length repeats: does transglutaminase activity play a role in (CAG)(n)/Q(n)-expansion diseases?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Tissue transglutaminase selectively modifies proteins associated with truncated mutant huntingtin in intact cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Transglutaminase bonds in neurofibrillary tangles and paired helical filament tau early in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Introducing transglutaminase into the study of Alzheimer's disease. A personal look back

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

Prolonged survival and decreased abnormal movements in transgenic model of Huntington disease, with administration of the transglutaminase inhibitor cystamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F62.1.14

21 January 2018

Identifiers

DOI

10.1093/JNEN/62.1.14

1 reference

22 September 2017

1 reference

PubMed ID

12528814