P38 mitogen-activated protein kinase inhibitor SB203580 has a bi-directional effect on iNOS expression and NO production (Q40691586)

22 September 2017

P38 mitogen-activated protein kinase inhibitor SB203580 has a bi-directional effect on iNOS expression and NO production (English)

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22 September 2017

2

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author name string

Aleksi Lahti

series ordinal

1

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PubMed ID

12421638

22 September 2017

Eeva Moilanen

series ordinal

3

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PubMed ID

12421638

22 September 2017

language of work or name

English

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publication date

1 November 2002

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European Journal of Pharmacology

22 September 2017

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22 September 2017

454

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22 September 2017

2-3

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22 September 2017

115-123

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Suppressors of cytokine signaling (SOCS): negative regulators of signal transduction.

22 September 2017

1 reference

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LPS and TNFalpha induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages.

7 January 2021

1 reference

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Direct Inhibition of Cyclooxygenase-1 and -2 by the Kinase Inhibitors SB 203580 and PD 98059

7 January 2021

1 reference

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

7 January 2021

1 reference

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Role of MAP kinase cascades in inducing arginine transporters and nitric oxide synthetase in RAW264 macrophages.

7 January 2021

1 reference

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Stabilization of interleukin-2 mRNA by the c-Jun NH2-terminal kinase pathway.

7 January 2021

1 reference

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Analysis of the cytokine-stimulated human inducible nitric oxide synthase (iNOS) gene: characterization of differences between human and mouse iNOS promoters

7 January 2021

1 reference

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The p38-MAPK inhibitor, SB203580, inhibits cardiac stress-activated protein kinases/c-Jun N-terminal kinases (SAPKs/JNKs)

7 January 2021

1 reference

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SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

7 January 2021

1 reference

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Role of interferon regulatory factor-1 and mitogen-activated protein kinase pathways in the induction of nitric oxide synthase-2 in retinal pigmented epithelial cells

7 January 2021

1 reference

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A Mycoplasma fermentans-derived synthetic lipopeptide induces AP-1 and NF-kappaB activity and cytokine secretion in macrophages via the activation of mitogen-activated protein kinase pathways

7 January 2021

1 reference

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p38 mitogen-activated protein kinase down-regulates nitric oxide and up-regulates prostaglandin E2 biosynthesis stimulated by interleukin-1beta

7 January 2021

1 reference

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Effect of SB 203580 on the activity of c-Raf in vitro and in vivo

7 January 2021

1 reference

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Involvement of the p38 mitogen-activated protein kinase pathway in transforming growth factor-beta-induced gene expression

7 January 2021

1 reference

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Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)

7 January 2021

1 reference

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A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion

7 January 2021

1 reference

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Upstream NF-kappaB site is required for the maximal expression of mouse inducible nitric oxide synthase gene in interferon-gamma plus lipopolysaccharide-induced RAW 264.7 macrophages

7 January 2021

1 reference

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Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway

7 January 2021

1 reference

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Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles

7 January 2021

1 reference

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Regulation of nitric oxide production in cultured human T84 intestinal epithelial cells by nuclear factor-kappa B-dependent induction of inducible nitric oxide synthase after exposure to bacterial endotoxin

7 January 2021

1 reference

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A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

7 January 2021

1 reference

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Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide

7 January 2021

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Nitric oxide and macrophage function

7 January 2021

1 reference

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p38 MAP kinase and MKK-1 co-operate in the generation of GM-CSF from LPS-stimulated human monocytes by an NF-kappa B-independent mechanism.

7 January 2021

1 reference

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Mitogen-activated protein kinase cascades and regulation of gene expression

7 January 2021

1 reference

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Endotoxin signal transduction in macrophages.

7 January 2021

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Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor beta

7 January 2021

1 reference

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Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide

7 January 2021

1 reference

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Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site

7 January 2021

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NF-kappa B regulates the LPS-induced expression of interleukin 12 p40 in murine peritoneal macrophages: roles of PKC, PKA, ERK, p38 MAPK, and proteasome

7 January 2021

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10.1016/S0014-2999(02)02490-1

7 January 2021

Identifiers

DOI

1 reference

22 September 2017

1 reference

PubMed ID

12421638