Formation and fate of nephrotoxic and cytotoxic glutathione S-conjugates: cysteine conjugate beta-lyase pathway (Q40693434)

22 September 2017

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title

Formation and fate of nephrotoxic and cytotoxic glutathione S-conjugates: cysteine conjugate beta-lyase pathway (English)

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22 September 2017

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Dekant W

1

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22 September 2017

Vamvakas S

series ordinal

2

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22 September 2017

Anders MW

series ordinal

3

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22 September 2017

publication date

1 January 1994

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22 September 2017

published in

Advances in Pharmacology

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22 September 2017

volume

27

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22 September 2017

page(s)

115-162

1 reference

Competition between transport of glutathione disulfide (GSSG) and glutathione S-conjugates from perfused rat liver into bile

22 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Histochemical Demonstration of Gamma-Glutamyl Transpeptidase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Interaction of AT-125, (αS,5S)-amino-3-chloro-4,5-dihydro-isoxazoleacetic acid, with bovine kidney γ-glutamyl transpeptidase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Nephrotoxic amino acid and glutathione S-conjugates: formation and renal activation

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Biosynthesis and biotransformation of glutathione S-conjugates to toxic metabolites

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Glutathione-dependent toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Direct evidence for inter-organ transport of glutathione and that the non-filtration renal mechanism for glutathione utilization involves gamma-glutamyl transpeptidase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Cleavage of S-(1,2-dichlorovinyl)-l-cysteine by an enzyme of bovine origin

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Intestinal amino acid transport: an overview

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

The interrelationship between P-glycoprotein and glutathionyl S-conjugate transporter(s)

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

ATP dependent primary active transport of xenobiotic-glutathione conjugates by human erythrocyte membrane

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Metabolism of propachlor by the germfree rat

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Metabolism of 2-acetamido-4-(chloromethyl)thiazole in germfree and conventional rats

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Metabolism of 2,4',5-trichlorobiphenyl by the mercapturic acid pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Biliary excretion and intestinal metabolism in the intermediary metabolism of pentachlorothioanisole

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Enzymes from bovine and turkey kidneys which cleave S-(1,2-dichlorovinyl)-l-cysteine

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Properties of DNA isolated from organs of calves treated with S-(1,2-dichlorovinyl)-L-cysteine. 3. Template activity for bacterial RNA polymerase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Properties of DNA isolated from tissues of calves treated with S-(1,2-dichlorovinyl)-L-cysteine. II. Primer-template activity for bacterial DNA polymerases

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Properties of DNA treated with S-(1,2-dichlorovinyl)-L-cysteine and a lyase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Modification of polynucleotides by a fragment produced by enzymatic cleavage of S-(1, 2-dichlorovinyl)-L-cysteine

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Hybridization of DNA modified by interaction with a metabolic fragment from S-(1,2-dichlorovinyl)-L-cysteine

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Mechanisms of cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

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Antagonistic action of a tumor promoter and a poly(adenosine diphosphoribose) synthesis inhibitor in radiation-induced transformation in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

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Biochemical mechanism of GSH depletion induced by 1,2-dibromoethane in isolated rat liver mitochondria. Evidence of a GSH conjugation process

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

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Calcium chelator Quin 2 prevents hydrogen-peroxide-induced DNA breakage and cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

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Prooxidant states and tumor promotion

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

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Response modification in carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Renal cysteine conjugate beta-lyase-mediated toxicity studied with primary cultures of human proximal tubular cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

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The role of glutathione and glutathione transferases in chemical carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

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Nephrotoxicity and hepatotoxicity of 1,1-dichloro-2,2-difluoroethylene in the rat. Indications for differential mechanisms of bioactivation

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Glutamine transaminase K and cysteine conjugate beta-lyase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

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S-(1,2-dichloro-[14C]vinyl)-L-cysteine (DCVC) in the mouse kidney: correlation between tissue-binding and toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Bacterial beta-lyase mediated cleavage and mutagenicity of cysteine conjugates derived from the nephrocarcinogenic alkenes trichloroethylene, tetrachloroethylene and hexachlorobutadiene

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Bioactivation mechanism of the cytotoxic and nephrotoxic S-conjugate S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Metabolism of hexachloro-1,3-butadiene in mice: in vivo and in vitro evidence for activation by glutathione conjugation

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Thioacylating agents as ultimate intermediates in the beta-lyase catalysed metabolism of S-(pentachloro-butadienyl)-L-cysteine

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Thioacylating intermediates as metabolites of S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2,2-trichlorovinyl)-L-cysteine formed by cysteine conjugate beta-lyase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Bioactivation of nephrotoxic haloalkenes by glutathione conjugation: formation of toxic and mutagenic intermediates by cysteine conjugate beta-lyase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Bioactivation of hexachlorobutadiene by glutathione conjugation

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

A mechanism of haloalkene-induced renal carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Metabolism of trichloroethene--in vivo and in vitro evidence for activation by glutathione conjugation.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Comparison of the distribution of microsomal and cytosolic glutathione S-transferase activities in different organs of the rat

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Preneoplastic lesions in rodent kidney induced spontaneously or by non-genotoxic agents: predictive nature and comparison to lesions induced by genotoxic carcinogens

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

The enzymatic reaction of chlorotrifluoroethylene with glutathione

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Assay of cysteine conjugate beta-lyase activity with S-(2-benzothiazolyl)cysteine as the substrate

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Enzymatic reaction of chlorotrifluoroethene with glutathione: 19F NMR evidence for stereochemical control of the reaction

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Conjugation of polychlorinated agrochemical sulphoxides and sulphones by glutathione

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Mechanism of S-(1,2-dichlorovinyl)glutathione-induced nephrotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Effects of biliary cannulation and buthionine sulphoximine pretreatment on the nephrotoxicity of para-aminophenol in the Fischer 344 rat.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Acetylation of S-substituted cysteines by a rat liver and kidney microsomal N-acetyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Structure/activity studies of the nephrotoxic and mutagenic action of cysteine conjugates of chloro- and fluoroalkenes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Role of lipid peroxidation in renal proximal tubule cell death induced by haloalkene cysteine conjugates

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Enzyme distribution along the nephron

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Immunochemical detection of covalently modified kidney proteins in S-(1,1,2,2,-tetrafluoroethyl)-L-cysteine-treated rats

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Stereochemistry of the microsomal glutathione S-transferase catalyzed addition of glutathione to chlorotrifluoroethene

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

A novel glutathione transferase (13-13) isolated from the matrix of rat liver mitochondria having structural similarity to class theta enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

In vivo detection and characterization of protein adducts resulting from bioactivation of haloethene cysteine S-conjugates by 19F NMR: chlorotrifluoroethene and tetrafluoroethene

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

The formation and biotransformation of cysteine conjugates of halogenated ethylenes by rabbit renal tubules

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Formation of difluorothionoacetyl-protein adducts by S-(1,1,2,2-tetrafluoroethyl)-L-cysteine metabolites: nucleophilic catalysis of stable lysyl adduct formation by histidine and tyrosine

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Formation of mitochondrial phospholipid adducts by nephrotoxic cysteine conjugate metabolites

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Localization and capacity of the last step of mercapturic acid biosynthesis and the reabsorption and acetylation of cysteine S-conjugates in the rat kidney

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Glutathione-degrading capacities of liver and kidney in different species

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

The nephrotoxicity of hexachloro-1:3-butadiene in the rat: studies of organic anion and cation transport in renal slices and the effect of monooxygenase inducers

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Specificity of a particulate rat renal peptidase and its localization along with other enzymes of mercapturic acid synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

The origin and characteristics of a pig kidney cell strain, LLC-PK

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Affinity Labeling of Rat-Kidney gamma-Glutamyl Transpeptidase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Renal transtubular transport of mercapturic acid in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Hepato-renal cooperation in biotransformation, membrane transport, and elimination of cysteine S-conjugates of xenobiotics

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Glutathione transport across hepatocyte plasma membranes. Analysis using isolated rat-liver sinusoidal-membrane vesicles

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Inter-organ metabolism and transport of a cysteine-S-conjugate of xenobiotics in normal and mutant analbuminemic rats

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Necrosis of the pars recta (S3 segment) of the rat kidney produced by hexachloro 1:3 butadiene

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

In vivo and in vitro nephrotoxicity of the cysteine conjugate of hexachlorobutadiene

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Chronic toxicity of S-(trans-1,2-dichlorovinyl)-L-cysteine in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Production of DNA single strand breaks in rabbit renal tissue after exposure to 1,2-dichlorovinylcysteine.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Cysteine conjugate beta-lyase and the thiomethyl shunt

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Properties of mitochondria treated with 1-chloro-2,4-dinitrobenzene

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Use of isolated kidney cells for study of drug metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

The formation of both a mono- and a bis-substituted glutathione conjugate of hexachlorobutadiene by isolated hepatocytes and following in vivo administration to the rat

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

The mechanism of pentachlorobutadienyl-glutathione nephrotoxicity studied with isolated rat renal epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Metabolism of the nephrotoxin dichloroacetylene by glutathione conjugation

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Metabolism of 14C-dichloroethyne in rats

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

p-Aminophenol nephrotoxicity: Biosynthesis of toxic glutathione conjugates

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Depletion by 1,2-dibromoethane, 1,2-dibromo-3-chloropropane, tris(2,3-dibromopropyl)phosphate, and hexachloro-1,3-butadiene of reduced non-protein sulfhydryl groups in target and non-target organs.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Results of a two year chronic toxicity study with hexachlorobutadiene in rats

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

The acute effects of S-(1,2-dichlorovinyl)-L-cysteine and related chemicals on renal function and ultrastructure in the pentobarbital-anesthetized dog: structure-activity relationships, biotransformation, and unique site-specific nephrotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Bioactivation of xenobiotics by formation of toxic glutathione conjugates

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Cytotoxicity of 2-bromo-(N-acetylcystein-S-yl)-hydroquinone isomers in rat renal tubular epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Resolution, purification and some properties of three glutathione transferases from rat liver mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Metabolism of mercapturic acid-pathway metabolites of 2-chloro-N-isopropylacetanilide (propachlor) by gastrointestinal bacteria

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Transport of glutathione by renal basal-lateral membrane vesicles

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Species differences in renal gamma-glutamyl transpeptidase activity do not correlate with susceptibility to 2-bromo-(diglutathion-S-yl)-hydroquinone nephrotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Studies on the mechanism of nephrotoxicity and nephrocarcinogenicity of halogenated alkenes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

The acute toxic effects of hexachloro-1 : 3-butadiene on the rat kidney

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

The oligomeric structure of rat liver microsomal glutathione transferase studied by chemical cross-linking

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Cysteine conjugate beta-lyase of rat kidney cytosol: characterization, immunocytochemical localization, and correlation with hexachlorobutadiene nephrotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Role of [Ca 2+ ] i in induction of c‐ fos , c‐ jun and c‐ myc mRNA in rat PTE after oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Glutathione transferases--structure and catalytic activity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Identification of the reactive glutathione conjugate S-(2-chloroethyl)glutathione in the bile of 1-bromo-2-chloroethane-treated rats by high-pressure liquid chromatography and precolumn derivatization with o-phthalaldehyde

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Stimulation of endogenous endonuclease activity in hepatocytes exposed to oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Enhancement of DMN-induced kidney tumors by 1,2-dichlorovinylcysteine in Swiss-Webster mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Differential toxicity as a result of apical and basolateral treatment of LLC-PK1 monolayers with S-(1,2,3,4,4-pentachlorobutadienyl)glutathione and N-acetyl-S-(1,2,3,4,4-pentachlorobutadienyl)-L-cysteine

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Cytotoxicity of S-(1,2,3,4,4-pentachlorobutadienyl)-L cysteine after apical and basolateral exposure of LLC-PK monolayers. Involvement of an amino acid transport system

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Formation and metabolism of a glutathione-S-conjugate in isolated rat liver and kidney cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Glutathione conjugate mediated toxicities

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

The distribution of microsomal glutathione transferase among different organelles, different organs, and different organisms

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Contrasting expression patterns of three members of the myc family of protooncogenes in the developing and adult mouse kidney

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

N-myc proto-oncogene expression during organogenesis in the developing mouse as revealed by in situ hybridization

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Glutathione-S-transferase-mediated methylthio displacement and turnover in the metabolism of pentachlorothioanisole by rats

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Sulfur-containing proreactive intermediates: hydrolysis and mutagenicity of halovinyl 2-nitrophenyl disulfides

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Nephrotoxicity of halogenated alkenyl cysteine-S-conjugates

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

The metabolism and disposition of hexachloro-1:3-butadiene in the rat and its relevance to nephrotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

The metabolism and nephrotoxicity of tetrafluoroethylene in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Properties of the microsomal and cytosolic glutathione transferases involved in hexachloro-1:3-butadiene conjugation

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Renal necrosis and DNA damage caused by selectively deuterated and methylated analogs of 1,2-dibromo-3-chloropropane in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Role of Ca2+ in toxic cell killing

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Metabolic activation of 1,2-dibromo-3-chloropropane: evidence for the formation of reactive episulfonium ion intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Glutathione S-transferases: gene structure, regulation, and biological function

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Effects of inhaled chlorotrifluoroethylene and hexafluoropropene on the rat kidney

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Evidence for the renal paratubular transport of glutathione

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Brush border membrane hydrolysis of S-benzyl-cysteine-p-nitroanilide, an activity of aminopeptidase M

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

The mutagenic effect of 1,2-dichloroethane on Salmonella typhimurium. II. activation by the isolated perfused rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

The mutagenic effect of 1,2-dichloroethane on Salmonella typhimurium I. Activation through conjugation with glutathion in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Influence of γ-Glutamyl Transpeptidase Inactivation on the Status of Extracellular Glutathione and Glutathione Conjugates

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

The inhibition of gamma-glutamyl transpeptidase and glutathione metabolism of isolated rat kidney cells by L-(alpha S, 5S)-alpha-amino-3-chloro-4, 5-dihydro-5-isoxazoleacetic acid (AT-125; NSC-163501)

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Neurotoxic effects of dichloroacetylene

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Carcinogenicity of dichloroacetylene: an inhalation study.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Formation of pentachlorothioanisole from N-acetyl-S-(pentachlorophenyl) cysteine in blood and liver of rats "in vivo".

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Oxidative stress in mitochondria: its relationship to cellular Ca2+ homeostasis, cell death, proliferation, and differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Chemically induced nephrotoxicity: role of metabolic activation

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Studies on the glutathione S-transferase activity associated with rat liver mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

A mechanism of S-(1,2,3,4,4-pentachloro-1,3-butadienyl)-L-cysteine toxicity to rabbit renal proximal tubules

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Pentachlorobutadienyl-L-cysteine uncouples oxidative phosphorylation by dissipating the proton gradient

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Covalent binding of hexachlorobutadiene metabolites to renal and hepatic mitochondrial DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

A comparative study on the effect of tumor promoters on poly ADP-ribosylation in A431 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Evidence for the active renal secretion of S-pentachlorophenyl-N-acetyl-L-cysteine by female rats

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Is the toxicity of cysteine conjugates formed during mercapturic acid biosynthesis relevant to the toxicity of covalently bound drug residues?

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Identification of a highly reactive threonine residue at the active site of gamma-glutamyl transpeptidase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

A C-S bond cleavage enzyme of cysteine conjugates in intestinal microorganisms

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Affinity labeling of gamma-glutamyl transpeptidase and location of the gamma-glutamyl binding site on the light subunit

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Serine-borate complex as a transition-state inhibitor of gamma-glutamyl transpeptidase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

A PATHOLOGICAL STUDY ON THE TOXICITY OF S-DICHLOROVINYL-L-CYSTEINE

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Purification and characterization of human hepatic cysteine-conjugate beta-lyase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Glutathione transferases and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Possible involvement of poly ADP-ribosylation in phenobarbital promotion of rat hepatocarcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Contraluminal para-aminohippurate (PAH) transport in the proximal tubule of the rat kidney. IV. Specificity: mono- and polysubstituted benzene analogs

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Contraluminal organic anion and cation transport in the proximal renal tubule: V. Interaction with sulfamoyl- and phenoxy diuretics, and with beta-lactam antibiotics

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Contraluminal para-aminohippurate (PAH) transport in the proximal tubule of the rat kidney. VI. Specificity: amino acids, their N-methyl-, N-acetyl- and N-benzoylderivatives; glutathione- and cysteine conjugates, di- and oligopeptides

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Formation of reactive intermediates by phase II enzymes: glutathione-dependent bioactivation reactions

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

The nephrotoxin dichlorovinylcysteine induces expression of the protooncogenesC-fos andC-myc in LLC-PK1 cells?A comparative investigation with growth factors and 12-O-tetradecanoylphorbolacetate

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Enzymatic transformation of mercapturic acids derived from halogenated alkenes to reactive and mutagenic intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

DNA-binding of sulfur-containing metabolites from 35S-(pentachlorobutadienyl)-L-cysteine in bacteria and isolated renal tubular cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Bacterial cysteine conjugate beta-lyase and the metabolism of cysteine S-conjugates: structural requirements for the cleavage of S-conjugates and the formation of reactive intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Mutagenicity of amino acid and glutathione S-conjugates in the Ames test

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Mutagenicity of hexachloro-1,3-butadiene and its S-conjugates in the Ames test--role of activation by the mercapturic acid pathway in its nephrocarcinogenicity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Metabolic activation of the nephrotoxic haloalkene 1,1,2-trichloro-3,3,3-trifluoro-1-propene by glutathione conjugation

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Cytotoxicity of cysteine S-conjugates: structure-activity relationships

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Genotoxicity of haloalkene and haloalkane glutathione S-conjugates in porcine kidney cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Mutagenicity of tetrachloroethene in the Ames test--metabolic activation by conjugation with glutathione.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Assessment of unscheduled DNA synthesis in a cultured line of renal epithelial cells exposed to cysteine S-conjugates of haloalkenes and haloalkanes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Events that precede and that follow S-(1,2-dichlorovinyl)-L-cysteine-induced release of mitochondrial Ca2+ and their association with cytotoxicity to renal cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Enhanced expression of the protooncogenes c-myc and c-fos in normal and malignant renal growth

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Glutathione transport across intestinal brush-border membranes: effects of ions, pH, delta psi, and inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Canalicular transport: discovery of ATP-dependent mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Glutathione S-conjugate formation from 1-chloro-2,4-dinitrobenzene and biliary S-conjugate excretion in the perfused rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Hepatic mitochondrial and cytosolic glutathione content and the subcellular distribution of GSH-S-transferases

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Toxicity of S-pentachlorobutadienyl-L-cysteine studied with isolated rat renal cortical mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

A urinary cysteine-halothane metabolite: validation and measurement in children

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

N-acetyl S-(1,2-dichlorovinyl)-L-cysteine produces a similar toxicity to S-(1,2-dichlorovinyl)-L-cysteine in rabbit renal slices: differential transport and metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

Transport and activation of S-(1,2-dichlorovinyl)-L-cysteine and N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine in rat kidney proximal tubules

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961031-5

7 January 2021

10.1016/S1054-3589(08)61031-5

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