Substitution of Trp1242 of TM17 alters substrate specificity of human multidrug resistance protein 3. (Q40696242)

22 September 2017

Substitution of Trp1242 of TM17 alters substrate specificity of human multidrug resistance protein 3. (English)

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22 September 2017

multiple drug resistance

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2

Roger G Deeley

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22 September 2017

Curtis J Oleschuk

1

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PubMed ID

12388190

22 September 2017

Susan P C Cole

series ordinal

3

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22 September 2017

9 October 2002

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American Journal of Physiology - Gastrointestinal and Liver Physiology

22 September 2017

1 reference

22 September 2017

284

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22 September 2017

2

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22 September 2017

G280-9

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Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteins

22 September 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

A family of drug transporters: the multidrug resistance-associated proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

Organ distribution of multidrug resistance proteins 1, 2, and 3 (Mrp1, 2, and 3) mRNA and hepatic induction of Mrp3 by constitutive androstane receptor activators in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

A naturally occurring mutation in MRP1 results in a selective decrease in organic anion transport and in increased doxorubicin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

Human MRP3 transporter: identification of the 5′-flanking region, genomic organization and alternative splice variants1The GenBank accession numbers of MRP3 and its splice variants MRP3A and MRP3B described in this paper are AF085690, AF085691 and

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

Membrane topology of the multidrug resistance protein (MRP). A study of glycosylation-site mutants reveals an extracytosolic NH2 terminus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

Characterization of the transport properties of cloned rat multidrug resistance-associated protein 3 (MRP3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

Function and regulation of ATP-binding cassette transport proteins involved in hepatobiliary transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

Enhanced expression of the human multidrug resistance protein 3 by bile salt in human enterocytes. A transcriptional control of a plausible bile acid transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

Single amino acid substitution of rat MRP2 results in acquired transport activity for taurocholate

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

cDNA cloning and inducible expression of human multidrug resistance associated protein 3 (MRP3)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

An inventory of the human ABC proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

MRP3, an organic anion transporter able to transport anti-cancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

21 January 2018

Bile salt transporters

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

Identification and functional analysis of two novel mutations in the multidrug resistance protein 2 gene in Israeli patients with Dubin-Johnson syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

Helical membrane protein folding, stability, and evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

Tissue distribution and induction of human multidrug resistant protein 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

Cellular localization and up-regulation of multidrug resistance-associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

Excretion of GSSG and glutathione conjugates mediated by MRP1 and cMOAT/MRP2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

Isolation of a novel human canalicular multispecific organic anion transporter, cMOAT2/MRP3, and its expression in cisplatin-resistant cancer cells with decreased ATP-dependent drug transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

Mutations in the canilicular multispecific organic anion transporter (cMOAT) gene, a novel ABC transporter, in patients with hyperbilirubinemia II/Dubin-Johnson syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

Characterization of drug transport by the human multidrug resistance protein 3 (ABCC3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

Identification of a nonconserved amino acid residue in multidrug resistance protein 1 important for determining substrate specificity: evidence for functional interaction between transmembrane helices 14 and 17.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

Identification of an amino acid residue in multidrug resistance protein 1 critical for conferring resistance to anthracyclines

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00331.2002

21 January 2018

Identifiers

DOI

10.1152/AJPGI.00331.2002

1 reference

22 September 2017

1 reference

PubMed ID

12388190