Hypoxic but not anoxic stabilization of HIF-1alpha requires mitochondrial reactive oxygen species (Q40698061)

22 September 2017

Hypoxic but not anoxic stabilization of HIF-1alpha requires mitochondrial reactive oxygen species (English)

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22 September 2017

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reactive oxygen species

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Clara Schroedl

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22 September 2017

David S McClintock

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2

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22 September 2017

G R Scott Budinger

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22 September 2017

Navdeep S Chandel

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22 September 2017

1 November 2002

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American Journal of Physiology - Lung Cellular and Molecular Physiology

22 September 2017

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22 September 2017

283

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22 September 2017

L922-31

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22 September 2017

5

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The NDUFA1 gene product (MWFE protein) is essential for activity of complex I in mammalian mitochondria

22 September 2017

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

A conserved family of prolyl-4-hydroxylases that modify HIF

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

Redox regulation of p53 during hypoxia

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

Conditionally lethal mutations in Chinese hamster cells. Characterization of a cell line with a possible defect in the krebs cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

Diphenylene iodonium inhibits the induction of erythropoietin and other mammalian genes by hypoxia. Implications for the mechanism of oxygen sensing

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22(phox)-containing NADPH oxidase

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

Rac1 activity is required for the activation of hypoxia-inducible factor 1.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

The relation of free radical production to hyperoxia

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

Intracellular diffusion gradients of O2 and ATP.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

Isolation of human cell lines lacking mitochondrial DNA.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

Divergent roles of glycolysis and the mitochondrial electron transport chain in hypoxic pulmonary vasoconstriction of the rat: identity of the hypoxic sensor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

Insulin-stimulated hydrogen peroxide reversibly inhibits protein-tyrosine phosphatase 1b in vivo and enhances the early insulin action cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

Bcl-2 family members and functional electron transport chain regulate oxygen deprivation-induced cell death

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

Molecular remedy of complex I defects: rotenone-insensitive internal NADH-quinone oxidoreductase of Saccharomyces cerevisiae mitochondria restores the NADH oxidase activity of complex I-deficient mammalian cells

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

Oxygen sensing and HIF-1 activation does not require an active mitochondrial respiratory chain electron-transfer pathway.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

Model for hypoxic pulmonary vasoconstriction involving mitochondrial oxygen sensing

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

A protective role for HIF-1 in response to redox manipulation and glucose deprivation: implications for tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00014.2002

10.1152/AJPLUNG.00014.2002

21 January 2018

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DOI

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22 September 2017

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