Formation, detection, and role in carcinogenesis of ethenobases in DNA. (Q40700878)

22 September 2017

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title

Formation, detection, and role in carcinogenesis of ethenobases in DNA. (English)

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22 September 2017

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Bartsch H

1

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22 September 2017

Barbin A

2

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22 September 2017

Marion MJ

3

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22 September 2017

Nair J

4

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22 September 2017

Guichard Y

5

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22 September 2017

language of work or name

English

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publication date

1 January 1994

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22 September 2017

Drug Metabolism Reviews

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22 September 2017

26

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22 September 2017

1-2

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22 September 2017

349-371

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Ethyl carbamate: analytical methodology, occurrence, formation, biological activity and risk assessment

22 September 2017

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

The Need for Epidemiological Studies of the Medical Exposures of Japanese Patients to the Carcinogen Ethyl Carhamate (Urethane) from 1950 to 1975

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Formation of 3,N4-ethenocytidine moieties in RNA by vinyl chloride metabolites in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Alkylation of RNA by vinyl bromide metabolites in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Alkylation of DNA and proteins in mice exposed to vinyl chloride

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Interactions of vinyl chloride with rat-liver DNA in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

1,N6-etheno-2'-deoxyadenosine and 3,N4-etheno-2'-deoxycytidine detected by monoclonal antibodies in lung and liver DNA of rats exposed to vinyl chloride.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Investigations on the relationship between DNA ethenobase adduct levels in several organs of vinyl chloride-exposed rats and cancer susceptibility.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Vinyl chloride-induced DNA adducts. I: Quantitative determination of N2,3-ethenoguanine based on electrophore labeling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Vinyl chloride-induced DNA adducts. II: Formation and persistence of 7-(2'-oxoethyl)guanine and N2,3-ethenoguanine in rat tissue DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Etheno adducts formed in DNA of vinyl chloride-exposed rats are highly persistent in liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Labeled 1,N6-ethenoadenosine and 3,N4-ethenocytidine in hepatic RNA of mice given[ethyl-1,2(-3)H or ethyl-1(-14)C]ethyl carbamate (urethan).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Alkylation of protein and DNA in mice treated with urethane

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Enzymatic oxidation of ethyl carbamate to vinyl carbamate and its role as an intermediate in the formation of 1,N6-ethenoadenosine.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

1,N6 formation, mutagenicity and murine tumor induction as indicators of the generation of an electrophilic epoxide metabolite of the closely related carcinogens ethyl carbamate (urethane) and vinyl carbamate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Synthesis and properties of vinyl carbamate epoxide, a possible ultimate electrophilic and carcinogenic metabolite of vinyl carbamate and ethyl carbamate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

1,N2-ethenodeoxyguanosine: properties and formation in chloroacetaldehyde-treated polynucleotides and DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Nucleophilic selectivity as a determinant of carcinogenic potency (TD50) in rodents: a comparison of mono- and bi-functional alkylating agents and vinyl chloride metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Fluorometric assay using high-pressure liquid chromatography for the microsomal metabolism of certain substituted aliphatics to 1,N6-ethenoadenine-forming metabolites.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Formation of 3,N4-ethenocytidine, 1,N6-ethenoadenosine, and 1,N2-ethenoguanosine in reactions of mucochloric acid with nucleosides

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Quantitative and kinetic examination of 32P-postlabeling of etheno-substituted nucleotides.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Studies on the miscoding properties of 1,N6-ethenoadenine and 3,N4-ethenocytosine, DNA reaction products of vinyl chloride metabolites, during in vitro DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Transcriptional errors and ambiguity resulting from the presence of 1,N6-ethenoadenosine or 3,N4-ethenocytidine in polyribonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

The vinyl chloride-derived nucleoside, N2,3-ethenoguanosine, is a highly efficient mutagen in transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

The vinyl chloride DNA derivative N2,3-ethenoguanine produces G----A transitions in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Evidence for the mutagenic potential of the vinyl chloride induced adduct, N2, 3-etheno-deoxyguanosine, using a site-directed kinetic assay

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Assessment of mutagenic efficiency of two carcinogen-modified nucleosides, 1,N6-ethenodeoxyadenosine and O4-methyldeoxythymidine, using polymerases of varying fidelity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Miscoding potential of N2,3-ethenoguanine studied in an Escherichia coli DNA-dependent RNA polymerase in vitro system and possible role of this adduct in vinyl chloride-induced mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

NMR studies of the exocyclic 1,N6-ethenodeoxyadenosine adduct (epsilon dA) opposite thymidine in a DNA duplex. Nonplanar alignment of epsilon dA(anti) and dT(anti) at the lesion site

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

NMR studies of the exocyclic 1,N6-ethenodeoxyadenosine adduct (epsilon dA) opposite deoxyguanosine in a DNA duplex. Epsilon dA(syn).dG(anti) pairing at the lesion site

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Both purified human 1,N6-ethenoadenine-binding protein and purified human 3-methyladenine-DNA glycosylase act on 1,N6-ethenoadenine and 3-methyladenine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Release of N2,3-ethenoguanine from chloroacetaldehyde-treated DNA by Escherichia coli 3-methyladenine DNA glycosylase II

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Activation of the cellular Harvey ras gene in mouse skin tumors initiated with urethane

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Detection of mutant Ha-ras genes in chemically initiated mouse skin epidermis before the development of benign tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Activating mutations of the c-Ha-ras protooncogene in chemically induced hepatomas of the male B6C3 F1 mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Proto-oncogene activation in liver tumors of hepatocarcinogenesis-resistant strains of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Genetic alterations in the 61st codon of the H-ras oncogene isolated from archival sections of hepatic hyperplasias, adenomas and carcinomas in control groups of B6C3F1 mouse bioassay studies conducted from 1979 to 1986

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Specific Ki-ras codon 61 mutations may determine the development of urethan-induced mouse lung adenomas or adenocarcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Comparison of Ki-ras gene mutation among simultaneously occurring multiple urethan-induced lung tumors in individual mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Multiple molecular alterations in mouse lung tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

Parental bias of Ki-ras oncogenes detected in lung tumors from mouse hybrids

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539409029802

10.3109/03602539409029802

21 January 2018

Identifiers

DOI

1 reference

22 September 2017

1 reference