Chimeric co-stimulatory molecules that selectively act through CD28 or CTLA-4 on human T cells (Q40712115)

23 September 2017

Chimeric co-stimulatory molecules that selectively act through CD28 or CTLA-4 on human T cells (English)

1 reference

23 September 2017

Sasha Lazetic

1

1 reference

23 September 2017

Steven R Leong

2

1 reference

23 September 2017

Jean C-C Chang

3

1 reference

23 September 2017

Randal Ong

4

1 reference

23 September 2017

Glenn Dawes

5

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23 September 2017

Juha Punnonen

6

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23 September 2017

language of work or name

English

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publication date

6 August 2002

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Journal of Biological Chemistry

23 September 2017

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23 September 2017

277

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23 September 2017

41

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23 September 2017

38660-38668

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The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses

23 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Structural mechanisms of costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Differential T cell costimulatory requirements in CD28-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

The role of B7-1/B7-2:CD28/CLTA-4 pathways in the prevention of anergy, induction of productive immunity and down-regulation of the immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accomp

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

B7 but not intercellular adhesion molecule-1 costimulation prevents the induction of human alloantigen-specific tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

B70 antigen is a second ligand for CTLA-4 and CD28.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Both extracellular immunoglobin-like domains of CD80 contain residues critical for binding T cell surface receptors CTLA-4 and CD28

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Differential recognition by CD28 of its cognate counter receptors CD80 (B7.1) and B70 (B7.2): analysis by site directed mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Solution structure of human CTLA-4 and delineation of a CD80/CD86 binding site conserved in CD28

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Structural basis for co-stimulation by the human CTLA-4/B7-2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Rapid evolution of a protein in vitro by DNA shuffling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

DNA shuffling of a family of genes from diverse species accelerates directed evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Evolution of a cytokine using DNA family shuffling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Molecular breeding of viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Directed evolution: the 'rational' basis for 'irrational' design.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Molecular breeding of allergy vaccines and antiallergic cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Genome shuffling leads to rapid phenotypic improvement in bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

21 January 2018

Cloning of cattle CD80.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Cloning and sequencing of the rabbit gene encoding T-cell costimulatory molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Tumor rejection after direct costimulation of CD8+ T cells by B7-transfected melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Engineering DNA vaccines via co-delivery of co-stimulatory molecule genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

The roles of MHC class II, CD40, and B7 costimulation in CTL induction by plasmid DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Cytotoxic T lymphocyte antigen-4 accumulation in the immunological synapse is regulated by TCR signal strength

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Surface cytotoxic T lymphocyte-associated antigen 4 partitions within lipid rafts and relocates to the immunological synapse under conditions of inhibition of T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Role of interleukin 10 in specific immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons gamma and alpha and prostaglandin E2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Immunoinhibitory DNA vaccine protects against autoimmune diabetes through cDNA encoding a selective CTLA-4 (CD152) ligand.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

Identification of residues in the V domain of CD80 (B7-1) implicated in functional interactions with CD28 and CTLA4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205808200

21 January 2018

Identifiers

DOI

10.1074/JBC.M205808200

1 reference

23 September 2017

1 reference