JM216-, JM118-, and cisplatin-induced cytotoxicity in relation to platinum-DNA adduct formation, glutathione levels and p53 status in human tumour cell lines with different sensitivities to cisplatin. (Q40721319)

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scientific article published on June 2002

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English	JM216-, JM118-, and cisplatin-induced cytotoxicity in relation to platinum-DNA adduct formation, glutathione levels and p53 status in human tumour cell lines with different sensitivities to cisplatin.	scientific article published on June 2002

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12093475%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

JM216-, JM118-, and cisplatin-induced cytotoxicity in relation to platinum-DNA adduct formation, glutathione levels and p53 status in human tumour cell lines with different sensitivities to cisplatin (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12093475%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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Elisabeth de Vries

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12093475%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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Eelco Fokkema

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10 November 2019

Harry J M Groen

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12093475%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Marco N Helder

3

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10 November 2019

Coby Meijer

5

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10 November 2019

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1 June 2002

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10 November 2019

Biochemical Pharmacology

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10 November 2019

63

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10 November 2019

11

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10 November 2019

1989-1996

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10 November 2019

An evaluation of the role of glutathione and its associated enzymes in the expression of differential sensitivities to antitumour agents shown by a range of human tumour cell lines.

1 reference

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7 January 2021

A study of human small-cell lung carcinoma (hSCLC) cell lines with different sensitivities to detect relevant mechanisms of cisplatin (CDDP) resistance

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The role of glutathione in resistance to cisplatin in a human small cell lung cancer cell line

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7 January 2021

Cisplatin-induced apoptosis and p53 gene status in a cisplatin-resistant human ovarian carcinoma cell line

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Determination of metabolites of a novel platinum anticancer drug JM216 in human plasma ultrafiltrates

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7 January 2021

Biotransformation of the platinum drug JM216 following oral administration to cancer patients.

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7 January 2021

Phase I study of oral JM216 given twice daily

1 reference

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7 January 2021

Phase II study of oral platinum drug JM216 as first-line treatment in patients with small-cell lung cancer

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7 January 2021

In vitro platinum drug chemosensitivity of human cervical squamous cell carcinoma cell lines with intrinsic and acquired resistance to cisplatin

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7 January 2021

Combined cytotoxic effects of tumor necrosis factor-alpha with various cytotoxic agents in tumor cell lines that are drug resistant due to mutated p53.

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7 January 2021

Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein

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7 January 2021

Cellular basis for differential sensitivity to cisplatin in human germ cell tumour and colon carcinoma cell lines.

1 reference

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7 January 2021

Immunocytochemical analysis of cisplatin-induced platinum-DNA adducts with double-fluorescence video microscopy

1 reference

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7 January 2021

DNA-binding properties of novel cis- and trans platinum-based anticancer agents in 2 human ovarian carcinoma cell lines

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7 January 2021

Intracellular metabolism of the orally active platinum drug JM216: influence of glutathione levels

1 reference

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7 January 2021

Gene-specific repair of Pt/DNA lesions and induction of apoptosis by the oral platinum drug JM216 in three human ovarian carcinoma cell lines sensitive and resistant to cisplatin

1 reference

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7 January 2021

Specificity of platinum–DNA adduct repair

1 reference

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7 January 2021

Effect of DNA polymerases and high mobility group protein 1 on the carrier ligand specificity for translesion synthesis past platinum-DNA adducts

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7 January 2021

Apoptosis and chemotherapy resistance

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Identifiers

10.1016/S0006-2952(02)00983-8

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12093475%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12093475%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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