MPP+ increases alpha-synuclein expression and ERK/MAP-kinase phosphorylation in human neuroblastoma SH-SY5Y cells (Q40725645)

23 September 2017

MPP+ increases alpha-synuclein expression and ERK/MAP-kinase phosphorylation in human neuroblastoma SH-SY5Y cells (English)

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23 September 2017

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2

Isidre Ferrer

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23 September 2017

Cristina Gómez-Santos

1

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23 September 2017

Julia Reiriz

3

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23 September 2017

Francesc Viñals

4

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23 September 2017

Marta Barrachina

5

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23 September 2017

Santiago Ambrosio

6

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23 September 2017

1 May 2002

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23 September 2017

8

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based on heuristic

inferred from page(s)

published in

Brain Research

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23 September 2017

935

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23 September 2017

1-2

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23 September 2017

32-39

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Wild-type but not Parkinson's disease-related ala-53 --> Thr mutant alpha -synuclein protects neuronal cells from apoptotic stimuli

23 September 2017

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https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

MPP+ toxicity in rat striatal slices: relationship between non-selective effects and free radical production

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Hydrogen peroxide activation of multiple mitogen-activated protein kinases in an oligodendrocyte cell line: role of extracellular signal-regulated kinase in hydrogen peroxide-induced cell death

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

MPP(+)-induced mitochondrial dysfunction is potentiated by dopamine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Interaction among mitochondria, mitogen-activated protein kinases, and nuclear factor-kappaB in cellular models of Parkinson's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Synucleins in synaptic plasticity and neurodegenerative disorders

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Characterisation of isolated alpha-synuclein filaments from substantia nigra of Parkinson's disease brain

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Survival function of ERK1/2 as IL-3-activated, staurosporine-resistant Bcl2 kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Aggregates from mutant and wild-type alpha-synuclein proteins and NAC peptide induce apoptotic cell death in human neuroblastoma cells by formation of beta-sheet and amyloid-like filaments

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Rat alpha-synuclein interacts with Tat binding protein 1, a component of the 26S proteasomal complex

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Low concentrations of 1-methyl-4-phenylpyridinium ion induce caspase-mediated apoptosis in human SH-SY5Y neuroblastoma cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Role of cytochrome c as a stimulator of alpha-synuclein aggregation in Lewy body disease

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

alpha-Synuclein forms a complex with transcription factor Elk-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Regulation of phospholipase D2: selective inhibition of mammalian phospholipase D isoenzymes by alpha- and beta-synucleins

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

alpha-synuclein binds to Tau and stimulates the protein kinase A-catalyzed tau phosphorylation of serine residues 262 and 356.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Release and aggregation of cytochrome c and alpha-synuclein are inhibited by the antiparkinsonian drugs, talipexole and pramipexole

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Enhanced vulnerability to oxidative stress by alpha-synuclein mutations and C-terminal truncation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Synuclein expression is decreased in rat substantia nigra following induction of apoptosis by intrastriatal 6-hydroxydopamine.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Sensitization of neuronal cells to oxidative stress with mutated human alpha-synuclein

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Novel alpha-synuclein-immunoreactive proteins in brain samples from the Contursi kindred, Parkinson's, and Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

The p42/p44 MAP kinase pathway prevents apoptosis induced by anchorage and serum removal

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Effect of the overexpression of wild-type or mutant alpha-synuclein on cell susceptibility to insult

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Staurosporine- and H-7-induced cell death in SH-SY5Y neuroblastoma cells is associated with caspase-2 and caspase-3 activation, but not with activation of the FAS/FAS-L-caspase-8 signaling pathway.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Alpha-synuclein and Parkinson's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Dopamine induces apoptosis through an oxidation-involved SAPK/JNK activation pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Alpha synuclein in neurodegenerative disorders: murderer or accomplice?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

JNK and p38 stresskinases--degenerative effectors of signal-transduction-cascades in the nervous system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Regulation of phospholipase D2 by H(2)O(2) in PC12 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Mitogen-activated protein kinase pathway mediates peroxynitrite-induced apoptosis in human dopaminergic neuroblastoma SH-SY5Y cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Constitutive phosphorylation of the Parkinson's disease associated alpha-synuclein

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Induction of neuronal death by α-synuclein

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

MPTP activates c-Jun NH(2)-terminal kinase (JNK) and its upstream regulatory kinase MKK4 in nigrostriatal neurons in vivo

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

The stress-activated protein kinase pathways

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Anisomycin affects both pro- and antiapoptotic mechanisms in PC12 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Confluence of vascular endothelial cells induces cell cycle exit by inhibiting p42/p44 mitogen-activated protein kinase activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Alpha-synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

Kinase suppressor of Ras is ceramide-activated protein kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2902422-8

10.1016/S0006-8993(02)02422-8

7 January 2021

Identifiers

DOI

1 reference

23 September 2017

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