Celecoxib induces apoptosis by inhibiting 3-phosphoinositide-dependent protein kinase-1 activity in the human colon cancer HT-29 cell line (Q40733087)

23 September 2017

Celecoxib induces apoptosis by inhibiting 3-phosphoinositide-dependent protein kinase-1 activity in the human colon cancer HT-29 cell line (English)

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23 September 2017

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6

Patrice Codogno

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23 September 2017

Sebastien Arico

1

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23 September 2017

Sophie Pattingre

2

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23 September 2017

Chantal Bauvy

3

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23 September 2017

Pierre Gane

4

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23 September 2017

Alain Barbat

5

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23 September 2017

Eric Ogier-Denis

7

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23 September 2017

language of work or name

English

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publication date

8 May 2002

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Journal of Biological Chemistry

23 September 2017

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23 September 2017

277

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23 September 2017

27613-27621

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23 September 2017

31

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Nonsteroidal antiinflammatory drugs and breast cancer

23 September 2017

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

Nonsteroidal anti-inflammatory drugs and colorectal cancer: evolving concepts of their chemopreventive actions

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

Aspirin use and potential mechanisms for colorectal cancer prevention

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201119200

Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

Inhibition of NF-kappa B by sodium salicylate and aspirin

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

Salicylate-induced growth arrest is associated with inhibition of p70s6k and down-regulation of c-myc, cyclin D1, cyclin A, and proliferating cell nuclear antigen

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

Sulindac sulfide inhibits Ras signaling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

COX-2-Specific inhibitors--the emergence of a new class of analgesic and anti-inflammatory drugs

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

Lack of cyclooxygenase-2 activity in HT-29 human colorectal carcinoma cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

A heterotrimeric Gi3-protein controls autophagic sequestration in the human colon cancer cell line HT-29.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

Resistance to high concentrations of methotrexate and 5-fluorouracil of differentiated HT-29 colon-cancer cells is restricted to cells of enterocytic phenotype

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

Akt signaling: linking membrane events to life and death decisions

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

Cytokine-induced apoptosis in epithelial HT-29 cells is independent of nitric oxide formation. Evidence for an interleukin-13-driven phosphatidylinositol 3-kinase-dependent survival mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201119200

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201119200

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201119200

3-phosphoinositide-dependent protein kinase 1, an Akt1 kinase, is involved in dephosphorylation of Thr-308 of Akt1 in Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201119200

Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

90-kDa ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

Rho GTPase control of protein kinase C-related protein kinase activation by 3-phosphoinositide-dependent protein kinase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201119200

Apoptosis signaling pathways mediated by cyclooxygenase-2 inhibitors in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201119200

COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201119200

The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201119200

Phosphoinositide 3-kinases in the gut: a link between inflammation and cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201119200

Evidence That 3-Phosphoinositide-dependent Protein Kinase-1 Mediates Phosphorylation of p70 S6 Kinasein Vivoat Thr-412 as well as Thr-252

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201119200

21 January 2018

Identifiers

DOI

10.1074/JBC.M201119200

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23 September 2017

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