Polyamine depletion prevents camptothecin-induced apoptosis by inhibiting the release of cytochrome c. (Q40733487)

23 September 2017

Polyamine depletion prevents camptothecin-induced apoptosis by inhibiting the release of cytochrome c. (English)

1 reference

23 September 2017

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Qing Yuan

1

1 reference

PubMed ID

11997243

23 September 2017

Ramesh M Ray

series ordinal

2

1 reference

PubMed ID

11997243

23 September 2017

Leonard R Johnson

series ordinal

3

1 reference

23 September 2017

1 June 2002

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American Journal of Physiology - Cell Physiology

23 September 2017

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23 September 2017

282

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23 September 2017

6

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23 September 2017

C1290-7

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Apoptosis induced by inhibition of intercellular contact

23 September 2017

1 reference

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Mitochondria and cell death. Mechanistic aspects and methodological issues

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Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.

21 January 2018

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Biochemical pathways of caspase activation during apoptosis

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Dissociation of mitochondrial depolarization from cytochrome c release during apoptosis induced by photodynamic therapy

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Dissecting the pathways to death

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Bcl-2 inhibits early apoptotic events and reveals post-mitotic multinucleation without affecting cell cycle arrest in human epithelial tumor cells exposed to etoposide.

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Bax-induced cytochrome C release from mitochondria is independent of the permeability transition pore but highly dependent on Mg2+ ions

21 January 2018

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Apoptosis in human disease: a new skin for the old ceremony?

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Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL.

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Collapse of the inner mitochondrial transmembrane potential is not required for apoptosis of HL60 cells.

21 January 2018

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Regulated targeting of BAX to mitochondria.

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Mitochondria and apoptosis

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BCL-2 family members and the mitochondria in apoptosis

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Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

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In vivo analysis of cadherin function in the mouse intestinal epithelium: essential roles in adhesion, maintenance of differentiation, and regulation of programmed cell death

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Bax directly induces release of cytochrome c from isolated mitochondria

21 January 2018

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Bcl-2-family proteins: the role of the BH3 domain in apoptosis.

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Withdrawal of IL-7 induces Bax translocation from cytosol to mitochondria through a rise in intracellular pH.

21 January 2018

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The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

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Death and survival signals determine active/inactive conformations of pro-apoptotic BAX, BAD, and BID molecules

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The mitochondrial death/life regulator in apoptosis and necrosis

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

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NF-kappaB activation and susceptibility to apoptosis after polyamine depletion in intestinal epithelial cells

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

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The mitochondrion in cell death control: certainties and incognita

21 January 2018

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Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

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The structure, function and evolution of cytochromes

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Increased intestinal Bak expression results in apoptosis.

21 January 2018

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Bcl-2 inhibits a Fas-induced conformational change in the Bax N terminus and Bax mitochondrial translocation.

21 January 2018

1 reference

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Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria

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Induction of apoptosis by excessive polyamine accumulation in ornithine decarboxylase-overproducing L1210 cells

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Epithelioid cell cultures from rat small intestine. Characterization by morphologic and immunologic criteria

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Cell death by apoptosis: basic concepts and disease relevance for the gastroenterologist

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Polyamine depletion delays apoptosis of rat intestinal epithelial cells

21 January 2018

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Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

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Molecular characterization of mitochondrial apoptosis-inducing factor

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Caspase-8 activation and bid cleavage contribute to MCF7 cellular execution in a caspase-3-dependent manner during staurosporine-mediated apoptosis

21 January 2018

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Caspases: enemies within

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Bcl-2 family: life-or-death switch

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Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria

21 January 2018

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TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

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Movement of Bax from the cytosol to mitochondria during apoptosis

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Signal transduction activated by the cancer chemopreventive isothiocyanates: cleavage of BID protein, tyrosine phosphorylation and activation of JNK

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Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

21 January 2018

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Bid, a critical mediator for apoptosis induced by the activation of Fas/TNF-R1 death receptors in hepatocytes

21 January 2018

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Putrescine does not support the migration and growth of IEC-6 cells

21 January 2018

1 reference

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Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis.

21 January 2018

1 reference

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Mitochondrial control of nuclear apoptosis.

21 January 2018

1 reference

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Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c

21 January 2018

1 reference

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10.1152/AJPCELL.00351.2001

21 January 2018

Identifiers

DOI

1 reference

23 September 2017

1 reference

PubMed ID

11997243