Suberoylanilide hydroxamic acid (SAHA) overcomes multidrug resistance and induces cell death in P-glycoprotein-expressing cells (Q40735439)

23 September 2017

Suberoylanilide hydroxamic acid (SAHA) overcomes multidrug resistance and induces cell death in P-glycoprotein-expressing cells (English)

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23 September 2017

multiple drug resistance

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5

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23 September 2017

Ricky W Johnstone

6

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author name string

Astrid A Ruefli

1

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23 September 2017

David Bernhard

2

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23 September 2017

Kellie M Tainton

3

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23 September 2017

Reinhard Kofler

4

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23 September 2017

language of work or name

English

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publication date

1 May 2002

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International Journal of Cancer

23 September 2017

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23 September 2017

99

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23 September 2017

2

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23 September 2017

292-298

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Apoptotic pathways: paper wraps stone blunts scissors

23 September 2017

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Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

21 January 2018

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Biochemistry of multidrug resistance mediated by the multidrug transporter

21 January 2018

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Human MDR 1 protein overexpression delays the apoptotic cascade in Chinese hamster ovary fibroblasts.

21 January 2018

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The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis

21 January 2018

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A new group of potent inducers of differentiation in murine erythroleukemia cells

21 January 2018

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Second generation hybrid polar compounds are potent inducers of transformed cell differentiation.

21 January 2018

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Eukaryotic transcriptional control

21 January 2018

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Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation

21 January 2018

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Induction of apoptosis in U937 human leukemia cells by suberoylanilide hydroxamic acid (SAHA) proceeds through pathways that are regulated by Bcl-2/Bcl-XL, c-Jun, and p21CIP1, but independent of p53

21 January 2018

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The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species

21 January 2018

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Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity

21 January 2018

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A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases.

21 January 2018

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Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.

21 January 2018

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Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.

21 January 2018

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Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

21 January 2018

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Equivalent Death of P-Glycoprotein Expressing and Nonexpressing Cells Induced by the Protein Kinase C Inhibitor Staurosporine

21 January 2018

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Reactive oxygen intermediates as mediators of programmed cell death in plants and animals

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.10327

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23 September 2017

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