Regulation of Ikappa B kinase (IKK)gamma /NEMO function by IKKbeta -mediated phosphorylation (Q40736146)

23 September 2017

Regulation of Ikappa B kinase (IKK)gamma /NEMO function by IKKbeta -mediated phosphorylation (English)

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23 September 2017

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Shashi Prajapati

1

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PubMed ID

11971901

23 September 2017

Richard B Gaynor

series ordinal

2

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PubMed ID

11971901

23 September 2017

language of work or name

English

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publication date

23 April 2002

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Journal of Biological Chemistry

23 September 2017

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23 September 2017

277

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23 September 2017

24331-24339

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23 September 2017

27

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NF-kappa B: ten years after

23 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

The NF-kappa B and I kappa B proteins: new discoveries and insights

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Bridging the gap: composition, regulation, and physiological function of the IkappaB kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Activators and target genes of Rel/NF-kappaB transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Identification and characterization of an IkappaB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Identification of a cell protein (FIP-3) as a modulator of NF-kappaB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

IkappaB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

HTLV-I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity and NF-kappaB activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Analysis of domains in the IKKalpha and IKKbeta proteins that regulate their kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

IKK1-deficient mice exhibit abnormal development of skin and skeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Limb and skin abnormalities in mice lacking IKKalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

IKKgamma mediates the interaction of cellular IkappaB kinases with the tax transforming protein of human T cell leukemia virus type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Role of IKKgamma/nemo in assembly of the Ikappa B kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Domain-specific interaction with the I kappa B kinase (IKK)regulatory subunit IKK gamma is an essential step in tax-mediated activation of IKK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKgamma) upon receptor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

The I kappa B kinase (IKK) complex is tripartite and contains IKK gamma but not IKAP as a regular component.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

CIKS, a connection to Ikappa B kinase and stress-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Genomic rearrangement in NEMO impairs NF-kappaB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Persistent activation of NF-kappa B by the tax transforming protein involves chronic phosphorylation of IkappaB kinase subunits IKKbeta and IKKgamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

DNA-dependent protein kinase phosphorylation of IkappaB alpha and IkappaB beta regulates NF-kappaB DNA binding properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Sites on FIP-3 (NEMO/IKKgamma) essential for its phosphorylation and NF-kappaB modulating activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Complete reconstitution of human IkappaB kinase (IKK) complex in yeast. Assessment of its stoichiometry and the role of IKKgamma on the complex activity in the absence of stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Signaling--2000 and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

Activation of the Ikappa B kinases by RIP via IKKgamma /NEMO-mediated oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201393200

21 January 2018

Identifiers

DOI

10.1074/JBC.M201393200

1 reference

23 September 2017

1 reference

PubMed ID

11971901