Signaling by the Mpl receptor involves IKK and NF-kappaB. (Q40736577)

23 September 2017

Signaling by the Mpl receptor involves IKK and NF-kappaB. (English)

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23 September 2017

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4

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7

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Ying Zhang

1

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23 September 2017

Shishinn Sun

2

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23 September 2017

Zhengyu Wang

3

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23 September 2017

Yulia Kaluzhny

5

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23 September 2017

Jeffrey Zimmet

6

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23 September 2017

language of work or name

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1 January 2002

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Journal of Cellular Biochemistry

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23 September 2017

85

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23 September 2017

3

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23 September 2017

523-535

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I kappa B: a specific inhibitor of the NF-kappa B transcription factor

23 September 2017

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Function and activation of NF-kappa B in the immune system

21 January 2018

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Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation

21 January 2018

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Expression of a constitutive NF-kappa B-like activity is essential for proliferation of cultured bovine vascular smooth muscle cells

21 January 2018

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Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

21 January 2018

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TRAF6 is a signal transducer for interleukin-1

21 January 2018

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Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

21 January 2018

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Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity

21 January 2018

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IKAP is a scaffold protein of the IkappaB kinase complex

21 January 2018

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Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

21 January 2018

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A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

21 January 2018

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Interaction of an NF-kappa B-like factor with a site upstream of the c-myc promoter

21 January 2018

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Phosphatidylinositol 3-kinase is necessary but not sufficient for thrombopoietin-induced proliferation in engineered Mpl-bearing cell lines as well as in primary megakaryocytic progenitors

21 January 2018

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Nuclear factor - kappaB-dependent regulation of p53 gene expression induced by daunomycin genotoxic drug

21 January 2018

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Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B

21 January 2018

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TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

21 January 2018

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Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

21 January 2018

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Differential regulation of the c-myc oncogene promoter by the NF-kappa B rel family of transcription factors

21 January 2018

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MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta

21 January 2018

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Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

21 January 2018

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NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

21 January 2018

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Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

21 January 2018

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21 January 2018

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Catalysis by a multiprotein IkappaB kinase complex

21 January 2018

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Cytokine-mediated transcriptional induction of the human inducible nitric oxide synthase gene requires both activator protein 1 and nuclear factor kappaB-binding sites

21 January 2018

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Involvement of prolonged ras activation in thrombopoietin-induced megakaryocytic differentiation of a human factor-dependent hematopoietic cell line

21 January 2018

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IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

21 January 2018

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Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1

21 January 2018

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Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase

21 January 2018

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Preclinical biology of megakaryocyte growth and development factor: a summary

21 January 2018

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Jak2 is essential for signaling through a variety of cytokine receptors

21 January 2018

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Stem cells. PTEN--coupling tumor suppression to stem cells?

21 January 2018

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Transcriptional regulation of the rat platelet factor 4 gene: interaction between an enhancer/silencer domain and the GATA site

21 January 2018

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Identification and characterization of an IkappaB kinase

21 January 2018

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Transforming-growth-factor-β activation elements in the distal promoter regions of the rat α1 type I collagen gene

21 January 2018

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The roles of phosphatidylinositol 3-kinase and protein kinase Czeta for thrombopoietin-induced mitogen-activated protein kinase activation in primary murine megakaryocytes

21 January 2018

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TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

21 January 2018

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IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

21 January 2018

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Control of thrombopoietin-induced megakaryocytic differentiation by the mitogen-activated protein kinase pathway

21 January 2018

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TGF-beta-activated kinase 1 stimulates NF-kappa B activation by an NF-kappa B-inducing kinase-independent mechanism

21 January 2018

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Multiple nuclear factors interact with the immunoglobulin enhancer sequences

21 January 2018

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Limb and skin abnormalities in mice lacking IKKalpha

21 January 2018

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Deregulated expression of c-myc in megakaryocytes of transgenic mice increases megakaryopoiesis and decreases polyploidization.

21 January 2018

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NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

21 January 2018

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The NF-kappaB binding site is essential for transcriptional activation of the IL-15 gene

21 January 2018

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IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

21 January 2018

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Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

21 January 2018

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Induction of interleukin-12 p40 transcript by CD40 ligation via activation of nuclear factor-kappaB.

21 January 2018

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The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

21 January 2018

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Ubiquitin-dependent degradation of cyclin B is accelerated in polyploid megakaryocytes.

21 January 2018

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Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha

21 January 2018

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In vivo effects of pegylated recombinant human megakaryocyte growth and development factor on hematopoiesis in normal mice

21 January 2018

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Mpl ligand (MGDF) alone and in combination with stem cell factor (SCF) promotes proliferation and survival of human megakaryocyte, erythroid and granulocyte/macrophage progenitors

21 January 2018

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Thrombopoietin alone stimulates the early proliferation and survival of human erythroid, myeloid and multipotential progenitors in serum-free culture

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCB.10141

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23 September 2017

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