Design, production, safety, evaluation, and clinical applications of nonprimate lentiviral vectors (Q40746258)

23 September 2017

Design, production, safety, evaluation, and clinical applications of nonprimate lentiviral vectors (English)

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23 September 2017

Jonathan B Rohll

1

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23 September 2017

Kyriacos A Mitrophanous

2

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23 September 2017

Enca Martin-Rendon

3

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23 September 2017

Fiona M Ellard

4

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23 September 2017

Pippa A Radcliffe

5

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23 September 2017

Nicholas D Mazarakis

6

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23 September 2017

Susan M Kingsman

7

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23 September 2017

language of work or name

English

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publication date

1 January 2002

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23 September 2017

Methods in Enzymology

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23 September 2017

346

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23 September 2017

466-500

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https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

23 September 2017

1 reference

7 January 2021

Stable gene transfer to the nervous system using a non-primate lentiviral vector

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Gene transfer vectors derived from equine infectious anemia virus

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Efficient transduction of nondividing cells by optimized feline immunodeficiency virus vectors.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Efficient transduction of nondividing human cells by feline immunodeficiency virus lentiviral vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Novel bovine lentiviral vectors based on Jembrana disease virus

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Lack of functional receptors is the only barrier that prevents caprine arthritis-encephalitis virus from infecting human cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Gene transfer systems derived from Visna virus: analysis of virus production and infectivity

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Canine cyclin T1 rescues equine infectious anemia virus tat trans-activation in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Conservation of amino-acid sequence motifs in lentivirus Vif proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Effects of long terminal repeat sequence variation on equine infectious anemia virus replication in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Long terminal repeat sequences of equine infectious anaemia virus are a major determinant of cell tropism

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Highly divergent lentiviral Tat proteins activate viral gene expression by a common mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Interactions between equine cyclin T1, Tat, and TAR are disrupted by a leucine-to-valine substitution found in human cyclin T1.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

THE HIV-1 REV PROTEIN

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https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

The ins and outs of HIV Rev.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Interactions among SR proteins, an exonic splicing enhancer, and a lentivirus Rev protein regulate alternative splicing

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Differential requirements for alternative splicing and nuclear export functions of equine infectious anemia virus Rev protein

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Binding of equine infectious anemia virus rev to an exon splicing enhancer mediates alternative splicing and nuclear export of viral mRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Sorting out the complexity of SR protein functions

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

The S2 gene of equine infectious anemia virus is a highly conserved determinant of viral replication and virulence properties in experimentally infected ponies

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Characterization of the equine infectious anaemia virus S2 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Incorporation of uracil into viral DNA correlates with reduced replication of EIAV in macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

A transient three-plasmid expression system for the production of high titer retroviral vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Selection of optimal polypurine tract region sequences during Moloney murine leukemia virus replication

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Replication of lengthened Moloney murine leukemia virus genomes is impaired at multiple stages

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

A Rev-independent human immunodeficiency virus type 1 (HIV-1)-based vector that exploits a codon-optimized HIV-1 gag-pol gene

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Rev-independent expression of synthetic gag-pol genes of human immunodeficiency virus type 1 and simian immunodeficiency virus: implications for the safety of lentiviral vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Pseudotypes of vesicular stomatitis virus determined by exogenous and endogenous avian RNA tumor viruses

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Inhibition of VSV binding and infectivity by phosphatidylserine: Is phosphatidylserine a VSV-binding site?

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Cell-surface marking of CD(34+)-restricted phenotypes of human hematopoietic progenitor cells by retrovirus-mediated gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Critical factors influencing stable transduction of human CD34(+) cells with HIV-1-derived lentiviral vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Lentiviral vectors pseudotyped with envelope glycoproteins derived from gibbon ape leukemia virus and murine leukemia virus 10A1.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Polypeptides of mammalian oncornaviruses. IV. Structural components of murine leukemia virus released as soluble antigens in cell culture

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Shedding and interspecies type sero-reactivity of the envelope glycopolypeptide gp120 of the human immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Analysis of 4070A envelope levels in retroviral preparations and effect on target cell transduction efficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

HIV-1 genome nuclear import is mediated by a central DNA flap

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Enhanced expression of transgenes from adeno-associated virus vectors with the woodchuck hepatitis virus posttranscriptional regulatory element: implications for gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Lentiviral vectors for enhanced gene expression in human hematopoietic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Effects of stoichiometry of retroviral components on virus production

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Dose-dependent transduction of vesicular stomatitis virus G protein-pseudotyped retrovirus vector into human solid tumor cell lines and murine fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

A stable system for the high-titer production of multiply attenuated lentiviral vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Generation of a stable cell line producing high-titer self-inactivating lentiviral vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

High throughput detection of retrovirus-associated reverse transcriptase using an improved fluorescent product enhanced reverse transcriptase assay and its comparison to conventional detection methods

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Advances in quantitative PCR technology: 5' nuclease assays

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Generation of retroviral packaging and producer cell lines for large-scale vector production and clinical application: improved safety and high titer

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Characterization of a replication-competent retrovirus resulting from recombination of packaging and vector sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Development of a novel trans-lentiviral vector that affords predictable safety

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Lentiviral vectors as a gene delivery system in the mouse midbrain: cellular and behavioral improvements in a 6-OHDA model of Parkinson's disease using GDNF.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

In vivo protection of nigral dopamine neurons by lentiviral gene transfer of the novel GDNF-family member neublastin/artemin

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Complete and long-term rescue of lesioned adult motoneurons by lentiviral-mediated expression of glial cell line-derived neurotrophic factor in the facial nucleus.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Reversal of pathology in the entire brain of mucopolysaccharidosis type VII mice after lentivirus-mediated gene transfer.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Quantitative analysis reveals expansion of human hematopoietic repopulating cells after short-term ex vivo culture

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Transduction of human CD34+ cells that mediate long-term engraftment of NOD/SCID mice by HIV vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Efficient transduction of human lymphocytes and CD34+ cells via human immunodeficiency virus-based gene transfer vectors.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Therapeutic haemoglobin synthesis in beta-thalassaemic mice expressing lentivirus-encoded human beta-globin

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Antiangiogenic gene therapy for cancer via systemic administration of adenoviral vectors expressing secretable endostatin

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Dominant effector genetics in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Monocyte maturation controls expression of equine infectious anemia virus

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Equine endothelial cells support productive infection of equine infectious anemia virus

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Translation of equine infectious anemia virus bicistronic tat-rev mRNA requires leaky ribosome scanning of the tat CTG initiation codon

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Equine infectious anemia virus trans-regulatory protein Rev controls viral mRNA stability, accumulation, and alternative splicing

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

dUTPase-minus caprine arthritis-encephalitis virus is attenuated for pathogenesis and accumulates G-to-A substitutions

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

High-titer human immunodeficiency virus type 1-based vector systems for gene delivery into nondividing cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Retroviral RNA packaging: sequence requirements and implications

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

An array of murine leukemia virus-related elements is transmitted and expressed in a primate recipient of retroviral gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Packaging of endogenous retroviral sequences in retroviral vectors produced by murine and human packaging cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

Rescue from photoreceptor degeneration in the rd mouse by human immunodeficiency virus vector-mediated gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

A third-generation lentivirus vector with a conditional packaging system

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2946072-7

7 January 2021

10.1016/S0076-6879(02)46072-7

Identifiers

DOI

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23 September 2017

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