Reconstituted discoidal ApoE-phospholipid particles are ligands for the scavenger receptor BI. The amino-terminal 1-165 domain of ApoE suffices for receptor binding. (Q40748661)

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scientific article published on 22 February 2002

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English	Reconstituted discoidal ApoE-phospholipid particles are ligands for the scavenger receptor BI. The amino-terminal 1-165 domain of ApoE suffices for receptor binding.	scientific article published on 22 February 2002

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7 December 2019

Reconstituted discoidal ApoE-phospholipid particles are ligands for the scavenger receptor BI. The amino-terminal 1-165 domain of ApoE suffices for receptor binding (English)

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7 December 2019

Vassilis I Zannis

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Xiaoping Li

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Horng-Yuan Kan

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Sophia Lavrentiadou

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Monty Krieger

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22 February 2002

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Journal of Biological Chemistry

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7 December 2019

21149-21157

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7 December 2019

Enhanced binding by cultured human fibroblasts of apo-E-containing lipoproteins as compared with low density lipoproteins

1 reference

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A plasma lipoprotein containing only apolipoprotein E and with gamma mobility on electrophoresis releases cholesterol from cells

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Inhibition of diet-induced atheroma formation in transgenic mice expressing apolipoprotein E in the arterial wall

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Charting the fate of the "good cholesterol": identification and characterization of the high-density lipoprotein receptor SR-BI.

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Dissociation of the high density lipoprotein and low density lipoprotein binding activities of murine scavenger receptor class B type I (mSR-BI) using retrovirus library-based activity dissection

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Identification of scavenger receptor SR-BI as a high density lipoprotein receptor

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The efficient cellular uptake of high density lipoprotein lipids via scavenger receptor class B type I requires not only receptor-mediated surface binding but also receptor-specific lipid transfer mediated by its extracellular domain

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21 January 2018

Transport of lipids from high and low density lipoproteins via scavenger receptor-BI.

1 reference

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21 January 2018

Scavenger receptor class B, type I-mediated uptake of various lipids into cells. Influence of the nature of the donor particle interaction with the receptor

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21 January 2018

Elevated triglyceride content diminishes the capacity of high density lipoprotein to deliver cholesteryl esters via the scavenger receptor class B type I (SR-BI).

1 reference

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21 January 2018

Scavenger receptor BI transfers major lipoprotein-associated phospholipids into the cells

1 reference

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21 January 2018

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Increased atherosclerosis in hyperlipidemic mice deficient in alpha -tocopherol transfer protein and vitamin E

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21 January 2018

Scavenger receptor class B, type I is expressed in porcine brain capillary endothelial cells and contributes to selective uptake of HDL-associated vitamin E

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21 January 2018

A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism

1 reference

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21 January 2018

Influence of the high density lipoprotein receptor SR-BI on reproductive and cardiovascular pathophysiology

1 reference

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21 January 2018

Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels

1 reference

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21 January 2018

Lower plasma levels and accelerated clearance of high density lipoprotein (HDL) and non-HDL cholesterol in scavenger receptor class B type I transgenic mice

1 reference

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21 January 2018

Biliary cholesterol excretion: a novel mechanism that regulates dietary cholesterol absorption

1 reference

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21 January 2018

The amino-terminal 1-185 domain of apoE promotes the clearance of lipoprotein remnants in vivo. The carboxy-terminal domain is required for induction of hyperlipidemia in normal and apoE-deficient mice.

1 reference

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21 January 2018

Domains of apolipoprotein E contributing to triglyceride and cholesterol homeostasis in vivo. Carboxyl-terminal region 203-299 promotes hepatic very low density lipoprotein-triglyceride secretion

1 reference

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21 January 2018

Interaction of nascent ApoE2, ApoE3, and ApoE4 isoforms expressed in mammalian cells with amyloid peptide beta (1-40). Relevance to Alzheimer's disease.

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21 January 2018

Structural basis for receptor binding heterogeneity of apolipoprotein E from type III hyperlipoproteinemic subjects

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21 January 2018

Expression of scavenger receptor class B, type I, by astrocytes and vascular smooth muscle cells in normal adult mouse and human brain and in Alzheimer's disease brain

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1 reference

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21 January 2018

High density lipoprotein phospholipid composition is a major determinant of the bi-directional flux and net movement of cellular free cholesterol mediated by scavenger receptor BI

1 reference

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21 January 2018

Scavenger receptor BI promotes high density lipoprotein-mediated cellular cholesterol efflux

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21 January 2018

Liver-specific overexpression of scavenger receptor BI decreases levels of very low density lipoprotein ApoB, low density lipoprotein ApoB, and high density lipoprotein in transgenic mice

1 reference

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21 January 2018

Decreased atherosclerosis in heterozygous low density lipoprotein receptor-deficient mice expressing the scavenger receptor BI transgene

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10.1074/JBC.M200658200

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7 December 2019

1 reference

Europe PubMed Central

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7 December 2019

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