Concomitant activation of the PI3K-Akt and the Ras-ERK signaling pathways is essential for transformation by the V-SEA tyrosine kinase oncogene (Q40750289)

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scientific article published on January 2002

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English	Concomitant activation of the PI3K-Akt and the Ras-ERK signaling pathways is essential for transformation by the V-SEA tyrosine kinase oncogene	scientific article published on January 2002

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scholarly article

1 reference

Europe PubMed Central

23 September 2017

Concomitant activation of the PI3K-Akt and the Ras-ERK signaling pathways is essential for transformation by the V-SEA tyrosine kinase oncogene (English)

1 reference

Europe PubMed Central

23 September 2017

author name string

Yehenew Agazie

1

1 reference

Europe PubMed Central

23 September 2017

Irene Ischenko

2

1 reference

Europe PubMed Central

23 September 2017

Michael Hayman

3

1 reference

Europe PubMed Central

23 September 2017

language of work or name

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publication date

1 January 2002

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Europe PubMed Central

23 September 2017

1 reference

Europe PubMed Central

23 September 2017

21

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Europe PubMed Central

23 September 2017

5

1 reference

Europe PubMed Central

23 September 2017

697-707

1 reference

Europe PubMed Central

23 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1205115

0 references

Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B

1 reference

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21 January 2018

Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily

1 reference

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21 January 2018

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

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21 January 2018

The catalytic subunit of phosphoinositide 3-kinase: requirements for oncogenicity

1 reference

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21 January 2018

Concomitant activation of pathways downstream of Grb2 and PI 3-kinase is required for MET-mediated metastasis.

1 reference

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21 January 2018

Binding and biological effects of insulin, insulin analogues and insulin-like growth factors in rat aortic smooth muscle cells. Comparison of maximal growth promoting activities

1 reference

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21 January 2018

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

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21 January 2018

Oncogenes and signal transduction

1 reference

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21 January 2018

Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205115

21 January 2018

Molecular cloning of a new transforming gene from a chemically transformed human cell line.

1 reference

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21 January 2018

Regulation of Sos activity by intramolecular interactions

1 reference

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21 January 2018

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

1 reference

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21 January 2018

The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product

1 reference

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21 January 2018

Interaction with the phosphotyrosine binding domain/phosphotyrosine interacting domain of SHC is required for the transforming activity of the FLT4/VEGFR3 receptor tyrosine kinase

1 reference

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21 January 2018

Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras

1 reference

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21 January 2018

New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway

1 reference

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21 January 2018

The putative transforming protein of S13 avian erythroblastosis virus is a transmembrane glycoprotein with an associated protein kinase activity.

1 reference

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21 January 2018

The protooncogene c-sea encodes a transmembrane protein-tyrosine kinase related to the Met/hepatocyte growth factor/scatter factor receptor

1 reference

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21 January 2018

Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells

1 reference

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21 January 2018

Identification and characterization of a new oncogene derived from the regulatory subunit of phosphoinositide 3-kinase

1 reference

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21 January 2018

Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

1 reference

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21 January 2018

Identification of two additional v-sea-encoded proteins in avian erythroblastosis virus, S13-infected fibroblasts

1 reference

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21 January 2018

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205115

21 January 2018

The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205115

21 January 2018

The tyrosines in the bidentate motif of the env-sea oncoprotein are essential for cell transformation and are binding sites for Grb2 and the tyrosine phosphatase SHP-2.

1 reference

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21 January 2018

Mechanism of met oncogene activation

1 reference

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21 January 2018

Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors

1 reference

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21 January 2018

Protein modules and signalling networks

1 reference

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21 January 2018

A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205115

21 January 2018

Specific uncoupling of GRB2 from the Met receptor. Differential effects on transformation and motility

1 reference

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21 January 2018

Activation of both MAP kinase and phosphatidylinositide 3-kinase by Ras is required for hepatocyte growth factor/scatter factor-induced adherens junction disassembly

1 reference

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21 January 2018

Bcl-2 family proteins

1 reference

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21 January 2018

Regulation of phosphatidylinositol 3'-kinase by tyrosyl phosphoproteins. Full activation requires occupancy of both SH2 domains in the 85-kDa regulatory subunit

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205115

21 January 2018

Activation of cdc42, rac, PAK, and rho-kinase in response to hepatocyte growth factor differentially regulates epithelial cell colony spreading and dissociation

1 reference

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21 January 2018

Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses

1 reference

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21 January 2018

The v-sea oncogene of avian erythroblastosis retrovirus S13: another member of the protein-tyrosine kinase gene family

1 reference

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21 January 2018

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

1 reference

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21 January 2018

Role of phosphatidylinositol 3-kinase and specific protein kinase B isoforms in the suppression of apoptosis mediated by the Abelson protein-tyrosine kinase

1 reference

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21 January 2018

The multisubstrate docking site of the MET receptor is dispensable for MET-mediated RAS signaling and cell scattering.

1 reference

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21 January 2018

Chicken macrophage stimulating protein is a ligand of the receptor protein-tyrosine kinase Sea.

1 reference

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21 January 2018

Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205115

21 January 2018

Engagement of Gab1 and Gab2 in erythropoietin signaling

1 reference

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21 January 2018

Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK kinase to Elk-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205115

21 January 2018

The cytokine hepatocyte growth factor/scatter factor inhibits apoptosis and enhances DNA repair by a common mechanism involving signaling through phosphatidyl inositol 3' kinase

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Gab-family adapter molecules in signal transduction of cytokine and growth factor receptors, and T and B cell antigen receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205115

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1205115

1 reference

Europe PubMed Central

23 September 2017

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1 reference

Europe PubMed Central

23 September 2017

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