Insulin-like growth factor (IGF)-binding protein-3 mutants that do not bind IGF-I or IGF-II stimulate apoptosis in human prostate cancer cells (Q40757983)

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scientific article published on 9 January 2002

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English	Insulin-like growth factor (IGF)-binding protein-3 mutants that do not bind IGF-I or IGF-II stimulate apoptosis in human prostate cancer cells	scientific article published on 9 January 2002

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scholarly article

1 reference

Europe PubMed Central

23 September 2017

Insulin-like growth factor (IGF)-binding protein-3 mutants that do not bind IGF-I or IGF-II stimulate apoptosis in human prostate cancer cells (English)

1 reference

Europe PubMed Central

23 September 2017

1 reference

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author name string

Jiang Hong

1

1 reference

Europe PubMed Central

23 September 2017

George Zhang

2

1 reference

Europe PubMed Central

23 September 2017

Feng Dong

3

1 reference

Europe PubMed Central

23 September 2017

Matthew M Rechler

4

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Europe PubMed Central

23 September 2017

language of work or name

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publication date

9 January 2002

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Europe PubMed Central

23 September 2017

number of pages

9

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Journal of Biological Chemistry

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Europe PubMed Central

23 September 2017

277

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Europe PubMed Central

23 September 2017

12

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Europe PubMed Central

23 September 2017

10489-10497

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Europe PubMed Central

23 September 2017

Insulin-like growth factor binding proteins and their role in controlling IGF actions

1 reference

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Insulin-like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-beta1 on programmed cell death through a p53- and IGF-independent mechanism

1 reference

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Direct functional interactions between insulin-like growth factor-binding protein-3 and retinoid X receptor-alpha regulate transcriptional signaling and apoptosis

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Insulin-like growth factor-binding protein-3 modulates expression of Bax and Bcl-2 and potentiates p53-independent radiation-induced apoptosis in human breast cancer cells

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The human insulin-like growth factor (IGF) binding protein-3 inhibits the growth of fibroblasts with a targeted disruption of the IGF-I receptor gene

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Growth inhibition and differentiation of the human colon carcinoma cell line, Caco-2, by constitutive expression of insulin-like growth factor binding protein-3.

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Growth inhibition by insulin-like growth factor-binding protein-3 in T47D breast cancer cells requires transforming growth factor-beta (TGF-beta ) and the type II TGF-beta receptor

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Transfection of human insulin-like growth factor-binding protein 3 gene inhibits cell growth and tumorigenicity: a cell culture model for lung cancer

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Phenotypic manifestations of insulin-like growth factor-binding protein-3 overexpression in transgenic mice

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Transforming growth factor-beta-induced cell growth inhibition in human breast cancer cells is mediated through insulin-like growth factor-binding protein-3 action.

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Insulin-like growth factor binding protein-3 and -5 are regulated by transforming growth factor-beta and retinoic acid in the human prostate adenocarcinoma cell line PC-3.

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Regulation of insulin-like growth factor 1 binding protein 3 levels by epidermal growth factor and retinoic acid in cervical epithelial cells

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Induction of the growth inhibitor IGF-binding protein 3 by p53

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Estradiol and antiestrogens regulate a growth inhibitory insulin-like growth factor binding protein 3 autocrine loop in human breast cancer cells

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1 alpha, 25-dihydroxy-16-ene-23-yne-26,27-hexafluorocholecalciferol (Ro24-5531) modulation of insulin-like growth factor-binding protein-3 and induction of differentiation and growth arrest in a human osteosarcoma cell line

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Insulin-like growth factors and their binding proteins: biological actions

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The 16-kDa Proteolytic Fragment of Insulin-Like Growth Factor (IGF) Binding Protein-3 Inhibits the Mitogenic Action of Fibroblast Growth Factor on Mouse Fibroblasts with a Targeted Disruption of the Type 1 IGF Receptor Gene

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Insulin-like growth factor-binding protein (IGFBP-3) predisposes breast cancer cells to programmed cell death in a non-IGF-dependent manner

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Characterization of the inhibition of DNA synthesis in proliferating mink lung epithelial cells by insulin-like growth factor binding protein-3.

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Antiproliferative effects of insulin-like growth factor-binding protein-3 in mesenchymal chondrogenic cell line RCJ3.1C5.18. relationship to differentiation stage

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Structure of the IGF-binding domain of the insulin-like growth factor-binding protein-5 (IGFBP-5): implications for IGF and IGF-I receptor interactions

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21 January 2018

Insulin-like growth factor (IGF) system components in human prostatic cancer cell-lines: LNCaP, DU145, and PC-3 cells

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21 January 2018

Cloning and expression of the growth hormone-dependent insulin-like growth factor-binding protein.

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21 January 2018

Binding sites and binding properties of binary and ternary complexes of insulin-like growth factor-II (IGF-II), IGF-binding protein-3, and acid-labile subunit

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21 January 2018

Substitutions for hydrophobic amino acids in the N-terminal domains of IGFBP-3 and -5 markedly reduce IGF-I binding and alter their biologic actions

1 reference

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21 January 2018

A 3-dimensional model for the insulin-like growth factor binding proteins (IGFBPs); supporting evidence using the structural determinants of the IGF binding site on IGFBP-3.

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21 January 2018

Ligand-binding characteristics of recombinant amino- and carboxyl-terminal fragments of human insulin-like growth factor-binding protein-3

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21 January 2018

Structural determinants of ligand and cell surface binding of insulin-like growth factor-binding protein-3

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21 January 2018

Structure-function analysis of the human insulin-like growth factor binding protein-4.

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21 January 2018

Overlap of IGF- and heparin-binding sites in rat IGF-binding protein-5.

1 reference

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21 January 2018

The interaction of insulin-like growth factor-I with the N-terminal domain of IGFBP-5

1 reference

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21 January 2018

Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study

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21 January 2018

Plasma levels of insulin-like growth factor-I and lung cancer risk: a case-control analysis.

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Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3.

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Insulin-like growth factor-I and binding protein-3 in relation to childhood leukaemia.

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21 January 2018

Differential insulin-like growth factor (IGF)-independent interactions of IGF binding protein-3 and IGF binding protein-5 on apoptosis in human breast cancer cells. Involvement of the mitochondria.

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Insulin-like growth factor (IGF) binding protein-3 inhibits type 1 IGF receptor activation independently of its IGF binding affinity

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Intranuclear localization of insulin-like growth factor binding protein-3 (IGFBP-3) during cell division in human keratinocytes

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Insulin-like growth factor-binding protein (IGFBP)-3 and IGFBP-5 share a common nuclear transport pathway in T47D human breast carcinoma cells.

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Nuclear import of insulin-like growth factor-binding protein-3 and -5 is mediated by the importin beta subunit

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Prostate carcinoma (PC-3) cell proliferation is stimulated by the 22-25-kDa proteolytic fragment (1-160) and inhibited by the 16-kDa fragment (1-95) of recombinant human insulin-like growth factor binding protein-3

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Smads as transcriptional co-modulators

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Identifiers

10.1074/JBC.M109604200

1 reference

Europe PubMed Central

23 September 2017

1 reference

Europe PubMed Central

23 September 2017

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