Wnt-1 and int-2 mammary oncogene effects on the beta-catenin pathway in immortalized mouse mammary epithelial cells are not sufficient for tumorigenesis. (Q40761371)

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English	Wnt-1 and int-2 mammary oncogene effects on the beta-catenin pathway in immortalized mouse mammary epithelial cells are not sufficient for tumorigenesis.	scientific article

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5 December 2019

Wnt-1 and int-2 mammary oncogene effects on the beta-catenin pathway in immortalized mouse mammary epithelial cells are not sufficient for tumorigenesis (English)

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5 December 2019

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5 December 2019

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Hollmann CA

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5 December 2019

Kittrell FS

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5 December 2019

Medina D

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1 November 2001

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5 December 2019

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5 December 2019

7645-7657

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5 December 2019

https://scigraph.springernature.com/pub.10.1038/sj.onc.1204980

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Nuclear endpoint of Wnt signaling: neoplastic transformation induced by transactivating lymphoid-enhancing factor 1.

1 reference

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21 January 2018

TCF/LEF factor earn their wings

1 reference

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21 January 2018

Excess beta-catenin promotes accumulation of transcriptionally active p53.

1 reference

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21 January 2018

Tumorigenesis by mouse mammary tumor virus: Proviral activation of a cellular gene in the common integration region int-2

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21 January 2018

Detection and characterization of the fibroblast growth factor-related oncoprotein INT-2.

1 reference

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21 January 2018

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

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21 January 2018

Differential regulation of the Wnt gene family during pregnancy and lactation suggests a role in postnatal development of the mammary gland

1 reference

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21 January 2018

FGF-3 and FGF-4 elicit distinct oncogenic properties in mouse mammary myoepithelial cells.

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21 January 2018

Identification of c-MYC as a target of the APC pathway

1 reference

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21 January 2018

Wnt-1 modulates cell-cell adhesion in mammalian cells by stabilizing beta-catenin binding to the cell adhesion protein cadherin

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21 January 2018

Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with beta-catenin

1 reference

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21 January 2018

Two proto-oncogenes implicated in mammary carcinogenesis, int-1 and int-2, are independently regulated during mouse development

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21 January 2018

Inhibition of gap junctional intercellular communication and delocalization of the cell adhesion molecule E-cadherin by tumor promoters

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21 January 2018

E-cadherin and its associated protein catenins, cancer invasion and metastasis

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Transfected MCF-7 cells as a model for breast-cancer progression

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Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

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The Wnt/Ca2+ pathway: a new vertebrate Wnt signaling pathway takes shape

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Transgenes expressing the Wnt-1 and int-2 proto-oncogenes cooperate during mammary carcinogenesis in doubly transgenic mice

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Increased expression of fibroblast growth factor 8 in human breast cancer.

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Fibroblast growth factor overexpressing breast carcinoma cells as models of angiogenesis and metastasis

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Immortalization phenotype dissociated from the preneoplastic phenotype in mouse mammary epithelial outgrowths in vivo

1 reference

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Radiation-induced tumorigenesis in preneoplastic mouse mammary glands in vivo: significance of p53 status and apoptosis.

1 reference

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21 January 2018

Signal transduction through beta-catenin and specification of cell fate during embryogenesis

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21 January 2018

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

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21 January 2018

Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15

1 reference

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21 January 2018

Mysterious liaisons: the relationship between c-Myc and the cell cycle.

1 reference

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21 January 2018

Activation of cellular gene by mouse mammary tumour virus may occur early in mammary tumour development

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21 January 2018

Stabilization of beta-catenin by genetic defects in melanoma cell lines

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The mechanism by which epidermal growth factor inhibits glycogen synthase kinase 3 in A431 cells

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Cooperative induction of mammary tumorigenesis by TGFalpha and Wnts

1 reference

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Induction of Mdm2 and enhancement of cell survival by bFGF.

1 reference

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21 January 2018

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

1 reference

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21 January 2018

Wnt signalling in mammalian development and cancer

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21 January 2018

Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling

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Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

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21 January 2018

Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice

1 reference

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21 January 2018

p53 function and dysfunction

1 reference

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Developmental and hormonal regulation of Wnt gene expression in the mouse mammary gland.

1 reference

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Cadherin-catenin complex: Protein interactions and their implications for cadherin function

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Interactions of apoptosis, proliferation and host age in the regression of the mouse mammary preneoplasia, TM3, carrying an unusual mutation in p53

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Differential temporal and spatial gene expression of fibroblast growth factor family members during mouse mammary gland development

1 reference

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7 January 2021

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Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability

1 reference

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7 January 2021

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int-2 oncogene amplification and prognosis in node-negative breast carcinoma

1 reference

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7 January 2021

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Fibroblast growth factors and their receptors

1 reference

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7 January 2021

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The int-2 gene product acts as an epithelial growth factor in transgenic mice

1 reference

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7 January 2021

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Identifiers

10.1038/SJ.ONC.1204980

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5 December 2019

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5 December 2019

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