A sensitive and quantitative assay for measuring cleavage of presenilin substrates (Q40763358)

23 September 2017

A sensitive and quantitative assay for measuring cleavage of presenilin substrates (English)

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23 September 2017

3

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23 September 2017

1

Helena Karlström

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23 September 2017

Anna Bergman

2

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23 September 2017

Jan Näslund

series ordinal

4

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23 September 2017

Johan Lundkvist

series ordinal

5

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23 September 2017

language of work or name

English

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publication date

13 December 2001

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Journal of Biological Chemistry

23 September 2017

4

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based on heuristic

inferred from page(s)

published in

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23 September 2017

277

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23 September 2017

9

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23 September 2017

6763-6766

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Amyloid, the presenilins and Alzheimer's disease

23 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C100649200

Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C100649200

Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C100649200

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C100649200

Total inactivation of gamma-secretase activity in presenilin-deficient embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C100649200

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C100649200

Detection of a novel intraneuronal pool of insoluble amyloid beta protein that accumulates with time in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C100649200

Polarized sorting of beta-amyloid precursor protein and its proteolytic products in MDCK cells is regulated by two independent signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C100649200

Presenilin is required for activity and nuclear access of Notch in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C100649200

L-685,458, an aspartyl protease transition state mimic, is a potent inhibitor of amyloid beta-protein precursor gamma-secretase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C100649200

Notch signaling: from the outside in

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C100649200

Presenilin-1 differentially facilitates endoproteolysis of the beta-amyloid precursor protein and Notch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C100649200

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C100649200

Endogenous beta-amyloid production in presenilin-deficient embryonic mouse fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C100649200

Aspartate mutations in presenilin and gamma-secretase inhibitors both impair notch1 proteolysis and nuclear translocation with relative preservation of notch1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C100649200

Mutation of conserved aspartates affects maturation of both aspartate mutant and endogenous presenilin 1 and presenilin 2 complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C100649200

Peptidomimetic probes and molecular modeling suggest that Alzheimer's gamma-secretase is an intramembrane-cleaving aspartyl protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C100649200

21 January 2018

Identifiers

DOI

10.1074/JBC.C100649200

1 reference

23 September 2017

1 reference