The activated glucocorticoid receptor modulates presumptive autoregulation of ribosomal protein S6 protein kinase, p70 S6K. (Q40769038)

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3 December 2019

title

The activated glucocorticoid receptor modulates presumptive autoregulation of ribosomal protein S6 protein kinase, p70 S6K (English)

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3 December 2019

2

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3 December 2019

author name string

O Jameel Shah

1

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3 December 2019

Angela Romanelli

3

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3 December 2019

Scot R Kimball

4

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3 December 2019

Leonard S Jefferson

5

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3 December 2019

language of work or name

English

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publication date

8 November 2001

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Journal of Biological Chemistry

3 December 2019

number of pages

9

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based on heuristic

inferred from page(s)

published in

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3 December 2019

volume

277

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3 December 2019

page(s)

2525-2533

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3 December 2019

issue

4

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The basic region of AP-1 specifies glucocorticoid receptor activity at a composite response element

3 December 2019

cites work

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Influence of a steroid receptor DNA-binding domain on transcriptional regulatory functions

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Intracellular receptors use a common mechanism to interpret signaling information at response elements

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Inhibition of p70/p85 S6 kinase activities in T cells by dexamethasone

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Among translational effectors, p70S6k is uniquely sensitive to inhibition by glucocorticoids

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Kinase phosphorylation: Keeping it all in the family

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Integrin-dependent activation of the p70 ribosomal S6 kinase signaling pathway

21 January 2018

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Hydrogen peroxide activates p70(S6k) signaling pathway

21 January 2018

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Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism

21 January 2018

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Oncogenic Raf-1 activates p70 S6 kinase via a mitogen-activated protein kinase-independent pathway

21 January 2018

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Leucine regulates translation of specific mRNAs in L6 myoblasts through mTOR-mediated changes in availability of eIF4E and phosphorylation of ribosomal protein S6.

21 January 2018

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Differential regulation by calcium reveals distinct signaling requirements for the activation of Akt and p70S6k

21 January 2018

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Activation of p70s6k is associated with phosphorylation of four clustered sites displaying Ser/Thr-Pro motifs

21 January 2018

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Dual requirement for a newly identified phosphorylation site in p70s6k

21 January 2018

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Multiple independent inputs are required for activation of the p70 S6 kinase

21 January 2018

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Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation

21 January 2018

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3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro

21 January 2018

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Phosphorylation sites in the autoinhibitory domain participate in p70(s6k) activation loop phosphorylation

21 January 2018

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Phosphorylation and activation of p70s6k by PDK1

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Coordination of cell growth with cell division

21 January 2018

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Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family

21 January 2018

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Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins

21 January 2018

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Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

21 January 2018

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Targeted disruption of p70(s6k) defines its role in protein synthesis and rapamycin sensitivity

21 January 2018

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Drosophila S6 kinase: a regulator of cell size

21 January 2018

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Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase

21 January 2018

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Structural and functional analysis of pp70S6k

21 January 2018

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Mutations in the glucocorticoid receptor zinc finger region that distinguish interdigitated DNA binding and transcriptional enhancement activities

21 January 2018

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Repeated immobilization stress increases total cytosolic glucocorticoid receptor in rat liver

21 January 2018

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I kappaB alpha-independent downregulation of NF-kappaB activity by glucocorticoid receptor.

21 January 2018

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Hormone-independent repression of AP-1-inducible collagenase promoter activity by glucocorticoid receptors

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Identifiers

DOI

10.1074/JBC.M105935200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11705993%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

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