Re-engineering adenovirus regulatory pathways to enhance oncolytic specificity and efficacy (Q40770884)

23 September 2017

Re-engineering adenovirus regulatory pathways to enhance oncolytic specificity and efficacy (English)

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23 September 2017

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Ramachandra M

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23 September 2017

Rahman A

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23 September 2017

Zou A

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23 September 2017

Vaillancourt M

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23 September 2017

Howe JA

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23 September 2017

Antelman D

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23 September 2017

Sugarman B

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23 September 2017

Demers GW

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23 September 2017

Engler H

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23 September 2017

Johnson D

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23 September 2017

Shabram P

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23 September 2017

1 November 2001

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11

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23 September 2017

1035-1041

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https://scigraph.springernature.com/pub.10.1038/nbt1101-1035

23 September 2017

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Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer

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A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites

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Tissue-specific expression of an anti-proliferative hybrid transgene from the human smooth muscle alpha-actin promoter suppresses smooth muscle cell proliferation and neointima formation

21 January 2018

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Binding and modulation of p53 by p300/CBP coactivators

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Retinoblastoma growth suppressor and a 300-kDa protein appear to regulate cellular DNA synthesis

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Tumor-selective transgene expression in vivo mediated by an E2F-responsive adenoviral vector.

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Does the antitumor adenovirus ONYX-015/dl1520 selectively target cells defective in the p53 pathway?

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Oncolytic virus therapy of multiple tumors in the brain requires suppression of innate and elicited antiviral responses

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An adenovirus type 5 early gene function regulates expression of other early viral genes

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Adenovirus VAI RNA is required for efficient translation of viral mRNAs at late times after infection

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Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection

21 January 2018

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Purification of a type 5 recombinant adenovirus encoding human p53 by column chromatography

21 January 2018

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Analytical anion-exchange HPLC of recombinant type-5 adenoviral particles

21 January 2018

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Retinoblastoma protein monoclonal antibodies with novel characteristics

21 January 2018

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Comparison of flow cytometry and laser scanning cytometry for the intracellular evaluation of adenoviral infectivity and p53 protein expression in gene therapy

21 January 2018

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An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Inhibition of p53-mediated transactivation and cell cycle arrest by E1A through its p300/CBP-interacting region

1 reference

https://api.crossref.org/works/10.1038%2FNBT1101-1035

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NBT1101-1035

1 reference

23 September 2017

1 reference