Antagonism of the actions of peroxisome proliferator-activated receptor-alpha by bile acids (Q40773905)

23 September 2017

Antagonism of the actions of peroxisome proliferator-activated receptor-alpha by bile acids (English)

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23 September 2017

Sinal CJ

1

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23 September 2017

Yoon M

series ordinal

2

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23 September 2017

Gonzalez FJ

series ordinal

3

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23 September 2017

language of work or name

English

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publication date

17 October 2001

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Journal of Biological Chemistry

23 September 2017

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23 September 2017

276

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23 September 2017

50

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23 September 2017

47154-47162

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The peroxisome proliferator-activated receptors: ligands and activators

23 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Central role of PPARalpha in the mechanism of action of hepatocarcinogenic peroxisome proliferators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Peroxisome proliferator-activated receptors: from genes to physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Roles of PPARs in health and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Peroxisome proliferator-activated receptor-alpha activators regulate genes governing lipoprotein metabolism, vascular inflammation and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Lipoprotein cholesterol uptake mediates up-regulation of bile-acid synthesis by increasing cholesterol 7alpha-hydroxylase but not sterol 27-hydroxylase gene expression in cultured rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Regulation of gene expression by dietary fat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

The peroxisome proliferator-activated receptor:retinoid X receptor heterodimer is activated by fatty acids and fibrate hypolipidaemic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Identification of a peroxisome proliferator-responsive element upstream of the human peroxisomal fatty acyl coenzyme A oxidase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Regulation of lipid and lipoprotein metabolism by PPAR activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Mechanisms of hepatocarcinogenicity of peroxisome-proliferating drugs and chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Identification of a peroxisome proliferator-responsive element upstream of the gene encoding rat peroxisomal enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Expression of putative fatty acid transporter genes are regulated by peroxisome proliferator-activated receptor alpha and gamma activators in a tissue- and inducer-specific manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Identification and characterization of DNA elements implicated in the regulation of CYP4A1 transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Peroxisome proliferator-activated receptor alpha controls the hepatic CYP4A induction adaptive response to starvation and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Fibrates increase human apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Mode of action of peroxisome proliferators as hypolipidemic drugs. Suppression of apolipoprotein C-III.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Influence of bezafibrate on hepatic cholesterol metabolism in gallstone patients: reduced activity of cholesterol 7 alpha-hydroxylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Regulation of bile acid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

The effect of peroxisome-proliferator-activated receptor-alpha on the activity of the cholesterol 7 alpha-hydroxylase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

The murine and human cholesterol 7alpha-hydroxylase gene promoters are differentially responsive to regulation by fatty acids mediated via peroxisome proliferator-activated receptor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

The peroxisome proliferator-activated receptor alpha (PPARalpha) regulates bile acid biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

A peroxisome proliferator-activated receptor gamma ligand inhibits adipocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Identification of a nuclear receptor for bile acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Bile acids: natural ligands for an orphan nuclear receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

The orphan nuclear receptor SHP inhibits agonist-dependent transcriptional activity of estrogen receptors ERalpha and ERbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms for repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

The short heterodimer partner receptor differentially modulates peroxisome proliferator-activated receptor alpha-mediated transcription from the peroxisome proliferator-response elements of the genes encoding the peroxisomal beta-oxidation enzymes a

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Peroxisome proliferator-activated receptor alpha inhibits hepatic S14 gene transcription. Evidence against the peroxisome proliferator-activated receptor alpha as the mediator of polyunsaturated fatty acid regulation of s14 gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

cDNA cloning and characterization of the transcriptional activities of the hamster peroxisome proliferator-activated receptor haPPAR gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Regulation of cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXRalpha).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Sequence and characterization of a coactivator for the steroid hormone receptor superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

p300 functions as a coactivator for the peroxisome proliferator-activated receptor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Identification of nuclear receptor corepressor as a peroxisome proliferator-activated receptor alpha interacting protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Regulation of bile acid synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

24-, 25- and 27-hydroxylation of cholesterol by a purified preparation of 27-hydroxylase from pig liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: a novel mechanism of feedback regulation of bile acid synthesis mediated by

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Transcriptional regulation of the human sterol 12alpha-hydroxylase gene (CYP8B1): roles of heaptocyte nuclear factor 4alpha in mediating bile acid repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

An orphan nuclear hormone receptor that lacks a DNA binding domain and heterodimerizes with other receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Novel receptor interaction and repression domains in the orphan receptor SHP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Peroxisome proliferator-activated receptors: three isotypes for a multitude of functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Interaction of some peroxisome proliferators with the mouse liver peroxisome proliferator-activated receptor (PPAR): a molecular modelling and quantitative structure-activity relationship (QSAR) study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Structure of the PPARalpha and -gamma ligand binding domain in complex with AZ 242; ligand selectivity and agonist activation in the PPAR family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Cholesterol and bile acids regulate cholesterol 7 alpha-hydroxylase expression at the transcriptional level in culture and in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Ligand-induced peroxisome proliferator-activated receptor alpha conformational change

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

Effects of different phenotypes of hyperlipoproteinemia and of treatment with fibric acid derivatives on the rates of cholesterol 7 alpha-hydroxylation in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107000200

21 January 2018

Identifiers

DOI

10.1074/JBC.M107000200

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23 September 2017

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