Rac affects invasion of human renal cell carcinomas by up-regulating tissue inhibitor of metalloproteinases (TIMP)-1 and TIMP-2 expression (Q40781214)

23 September 2017

Rac affects invasion of human renal cell carcinomas by up-regulating tissue inhibitor of metalloproteinases (TIMP)-1 and TIMP-2 expression (English)

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23 September 2017

Engers R

1

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23 September 2017

Springer E

2

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23 September 2017

Michiels F

3

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23 September 2017

Collard JG

4

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23 September 2017

Gabbert HE

5

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23 September 2017

language of work or name

English

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publication date

10 September 2001

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Journal of Biological Chemistry

23 September 2017

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23 September 2017

276

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23 September 2017

45

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23 September 2017

41889-41897

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Mechanisms of tumor metastasis: cell biological aspects and clinical implications

23 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Rho GTPases and the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Rho family proteins in cell adhesion and cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

A role for Rac in Tiam1-induced membrane ruffling and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

The Small GTPases Rho and Rac Are Required for the Establishment of Cadherin-dependent Cell–Cell Contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Inhibition of invasion of epithelial cells by Tiam1-Rac signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Regulation of cell-cell adhesion of MDCK cells by Cdc42 and Rac1 small GTPases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Leptin promotes invasiveness of kidney and colonic epithelial cells via phosphoinositide 3-kinase-, rho-, and rac-dependent signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Regulation of cadherin function by Rho and Rac: modulation by junction maturation and cellular context.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Activation of the small GTPase Rac is sufficient to disrupt cadherin-dependent cell-cell adhesion in normal human keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Role of Rac1 and oxygen radicals in collagenase-1 expression induced by cell shape change

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Changing views of the role of matrix metalloproteinases in metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Tissue inhibitors of metalloproteases: regulation and biological activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Tissue inhibitors of metalloproteinases: evolution, structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Specific, high affinity binding of tissue inhibitor of metalloproteinases-4 (TIMP-4) to the COOH-terminal hemopexin-like domain of human gelatinase A. TIMP-4 binds progelatinase A and the COOH-terminal domain in a similar manner to TIMP-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Inhibition of tumor growth and metastasis of human breast cancer cells transfected with tissue inhibitor of metalloproteinase 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Inhibition of invasion and induction of apoptotic cell death of cancer cell lines by overexpression of TIMP-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Tiam1 mutations in human renal-cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

In vitro invasiveness of human epithelioid-sarcoma cell lines: association with cell motility and inverse correlation with the expression of tissue inhibitor of metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Involvement of the tyrosine kinase fer in cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

The C-terminal region of membrane type matrix metalloproteinase is a functional transmembrane domain required for pro-gelatinase A activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Growth inhibition in clonal subpopulations of a human epithelioid sarcoma cell line by retinoic acid and tumour necrosis factor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Transcriptional activity of the human tissue inhibitor of metalloproteinases 1 (TIMP-1) gene in fibroblasts involves elements in the promoter, exon 1 and intron 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Targeting of Tiam1 to the plasma membrane requires the cooperative function of the N-terminal pleckstrin homology domain and an adjacent protein interaction domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Rac and Cdc42 are potent stimulators of E2F-dependent transcription capable of promoting retinoblastoma susceptibility gene product hyperphosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

ECM and cell surface proteolysis: regulating cellular ecology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Matrix metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Functional interplay between type I collagen and cell surface matrix metalloproteinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Proinflammatory cytokines regulate tissue inhibitors of metalloproteinases and disintegrin metalloproteinase in cardiac cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Structure and characterization of the human tissue inhibitor of metalloproteinases-2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

rac1 regulates a cytokine-stimulated, redox-dependent pathway necessary for NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Effectors for the Rho GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Organization and regulation of mitogen-activated protein kinase signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

Multiple signals converging on NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105049200

21 January 2018

Identifiers

DOI

10.1074/JBC.M105049200

1 reference

23 September 2017

1 reference