Poly(ADP-ribose) polymerase inhibitors attenuate necrotic but not apoptotic neuronal death in experimental models of cerebral ischemia (Q40783272)

23 September 2017

Poly(ADP-ribose) polymerase inhibitors attenuate necrotic but not apoptotic neuronal death in experimental models of cerebral ischemia (English)

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23 September 2017

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Moroni F

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23 September 2017

Meli E

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23 September 2017

Peruginelli F

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23 September 2017

Chiarugi A

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23 September 2017

Cozzi A

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23 September 2017

Picca R

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23 September 2017

Romagnoli P

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23 September 2017

Pellicciari R

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23 September 2017

Pellegrini-Giampietro DE

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23 September 2017

1 September 2001

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Cell Death & Differentiation

23 September 2017

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23 September 2017

8

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23 September 2017

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23 September 2017

921-932

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4400884

23 September 2017

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Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders?

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7 January 2021

1-Aminoindan-1,5-dicarboxylic acid and (S)-(+)-2-(3'-carboxybicyclo[1.1.1] pentyl)-glycine, two mGlu1 receptor-preferring antagonists, reduce neuronal death in in vitro and in vivo models of cerebral ischaemia

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7 January 2021

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7 January 2021

Free radicals and the pathogenesis of neuronal death: cooperative role of excitatory amino acids

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7 January 2021

Glutamate, nitric oxide and cell-cell signalling in the nervous system

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7 January 2021

Poly(ADP-ribose) polymerase: early involvement in glutamate-induced neurotoxicity in cultured cerebellar granule cells

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7 January 2021

Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity

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7 January 2021

Poly(ADP-ribose) polymerase: a molecular nick-sensor

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7 January 2021

Streptozotocin and alloxan induce DNA strand breaks and poly(ADP–ribose) synthetase in pancreatic islets

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7 January 2021

Poly(ADP-ribose) polymerase inhibitors preserve oxidized nicotinamide adenine dinucleotide and adenosine 5'-triphosphate pools in DNA-damaged cells: mechanism of stimulation of unscheduled DNA synthesis

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7 January 2021

Oxidant injury of cells. DNA strand-breaks activate polyadenosine diphosphate-ribose polymerase and lead to depletion of nicotinamide adenine dinucleotide

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7 January 2021

Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion

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7 January 2021

Poly (ADP-ribose) polymerase, nitric oxide and cell death

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7 January 2021

Poly(ADP-ribose) polymerase-1 in the nervous system

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7 January 2021

Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase.

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7 January 2021

Enhanced poly(ADP-ribosyl)ation after focal ischemia in rat brain.

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7 January 2021

Post-treatment with an inhibitor of poly(ADP-ribose) polymerase attenuates cerebral damage in focal ischemia.

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7 January 2021

Neuroprotective effects of inhibiting poly(ADP-ribose) synthetase on focal cerebral ischemia in rats.

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7 January 2021

Inhibition of poly(ADP-ribose) polymerase: reduction of ischemic injury and attenuation of N-methyl-D-aspartate-induced neurotransmitter dysregulation

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7 January 2021

Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.

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7 January 2021

Protection with metabotropic glutamate 1 receptor antagonists in models of ischemic neuronal death: time-course and mechanisms

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7 January 2021

2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia.

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7 January 2021

The glycine antagonist and free radical scavenger 7-Cl-thio-kynurenate reduces CA1 ischemic damage in the gerbil

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7 January 2021

Kynurenine hydroxylase inhibitors reduce ischemic brain damage: studies with (m-nitrobenzoyl)-alanine (mNBA) and 3,4-dimethoxy-[-N-4-(nitrophenyl)thiazol-2yl]-benzenesulfonamide (Ro 61-8048) in models of focal or global brain ischemia.

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7 January 2021

Benzamide, an inhibitor of poly(ADP-ribose) polymerase, attenuates methamphetamine-induced dopamine neurotoxicity in the C57B1/6N mouse

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7 January 2021

Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: A perspective on the contributions of apoptosis and necrosis.

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7 January 2021

Neuronal cell death: a demise with different shapes.

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7 January 2021

Calpain and caspase: can you tell the difference?

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7 January 2021

Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Staurosporine-induced neuronal apoptosis.

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Apoptosis in the absence of poly-(ADP-ribose) polymerase

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Neuronal death in nigral grafts in the absence of poly (ADP-ribose) polymerase activation

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7 January 2021

Effects of inhibitors of the activity of poly (ADP-ribose) synthetase on the liver injury caused by ischaemia-reperfusion: a comparison with radical scavengers

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7 January 2021

Importance of poly(ADP-ribose) polymerase and its cleavage in apoptosis. Lesson from an uncleavable mutant

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7 January 2021

Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Slowly triggered excitotoxicity occurs by necrosis in cortical cultures.

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7 January 2021

Apoptotic features of selective neuronal death in ischemia, epilepsy and gp 120 toxicity

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7 January 2021

Pathobiology of ischaemic stroke: an integrated view

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

The changing landscape of ischaemic brain injury mechanisms.

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Combined oxygen and glucose deprivation in cortical cell culture: calcium-dependent and calcium-independent mechanisms of neuronal injury.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Caspase inhibitors are functionally neuroprotective against oxygen glucose deprivation induced CA1 death in rat organotypic hippocampal slices

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

A simple in vitro model of ischemia based on hippocampal slice cultures and propidium iodide fluorescence.

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Ultrastructural morphological changes are not characteristic of apoptotic cell death following focal cerebral ischaemia in the rat.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Histopathologic clues to the pathways of neuronal death following ischemia/hypoxia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Very delayed infarction after mild focal cerebral ischemia: a role for apoptosis?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Blockade of glutamate receptors unmasks neuronal apoptosis after oxygen-glucose deprivation in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Caspase inhibition selectively reduces the apoptotic component of oxygen-glucose deprivation-induced cortical neuronal cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Internucleosomal DNA cleavage involved in ischemia-induced neuronal death

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Global ischemia induces apoptosis-associated genes in hippocampus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Transient poly(ADP-ribosyl)ation of nuclear proteins and role of poly(ADP-ribose) polymerase in the early stages of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Caspases: killer proteases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

The regional vulnerability to hypoglycemia-induced neurotoxicity in organotypic hippocampal culture: protection by early tetrodotoxin or delayed MK-801.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Glutamate and non-glutamate receptor mediated toxicity caused by oxygen and glucose deprivation in organotypic hippocampal cultures

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Protection from neuronal damage induced by combined oxygen and glucose deprivation in organotypic hippocampal cultures by glutamate receptor antagonists

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Mechanisms and effects of intracellular calcium buffering on neuronal survival in organotypic hippocampal cultures exposed to anoxia/aglycemia or to excitotoxins.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Neuroprotection by both NMDA and non-NMDA receptor antagonists in in vitro ischemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400884

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4400884

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Dimensions Publication ID

23 September 2017

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