The Vam6 and Gtr1-Gtr2 pathway activates TORC1 in response to amino acids in fission yeast (Q40786022)

23 September 2017

The Vam6 and Gtr1-Gtr2 pathway activates TORC1 in response to amino acids in fission yeast (English)

1 reference

23 September 2017

Noelia Valbuena

1

1 reference

23 September 2017

Kun-Liang Guan

series ordinal

2

1 reference

23 September 2017

Sergio Moreno

series ordinal

3

1 reference

23 September 2017

language of work or name

English

0 references

publication date

17 February 2012

1 reference

23 September 2017

Journal of Cell Science

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23 September 2017

125

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23 September 2017

Pt 8

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23 September 2017

1920-1928

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describes a project that uses

23 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3656621/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

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Fission yeast TORC1 regulates phosphorylation of ribosomal S6 proteins in response to nutrients and its activity is inhibited by rapamycin

24 September 2017

1 reference

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The Vam6 GEF controls TORC1 by activating the EGO complex

24 September 2017

1 reference

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TOR1 and TOR2 have distinct locations in live cells

24 September 2017

1 reference

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Regulation of TORC1 by Rag GTPases in nutrient response

24 September 2017

1 reference

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The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

24 September 2017

1 reference

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A pathway for phagosome maturation during engulfment of apoptotic cells

24 September 2017

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HOPS proofreads the trans-SNARE complex for yeast vacuole fusion

24 September 2017

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Point mutations in TOR confer Rheb-independent growth in fission yeast and nutrient-independent mammalian TOR signaling in mammalian cells

24 September 2017

1 reference

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Loss of the TOR kinase Tor2 mimics nitrogen starvation and activates the sexual development pathway in fission yeast.

24 September 2017

1 reference

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Cell growth control: little eukaryotes make big contributions.

24 September 2017

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The TOR signalling network from yeast to man.

24 September 2017

1 reference

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The TOR and EGO protein complexes orchestrate microautophagy in yeast

24 September 2017

1 reference

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Rheb binds and regulates the mTOR kinase

24 September 2017

1 reference

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The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses

24 September 2017

1 reference

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

24 September 2017

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Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

24 September 2017

1 reference

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Upstream and downstream of mTOR

24 September 2017

1 reference

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Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

24 September 2017

1 reference

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Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

24 September 2017

1 reference

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Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E

24 September 2017

1 reference

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Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B

24 September 2017

1 reference

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New component of the vacuolar class C-Vps complex couples nucleotide exchange on the Ypt7 GTPase to SNARE-dependent docking and fusion

24 September 2017

1 reference

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Proteins needed for vesicle budding from the Golgi complex are also required for the docking step of homotypic vacuole fusion

24 September 2017

1 reference

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Saccharomyces cerevisiae putative G protein, Gtr1p, which forms complexes with itself and a novel protein designated as Gtr2p, negatively regulates the Ran/Gsp1p G protein cycle through Gtr2p

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656621

Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656621

Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656621

Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast

24 September 2017

1 reference

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RagA is a functional homologue of S. cerevisiae Gtr1p involved in the Ran/Gsp1-GTPase pathway

24 September 2017

1 reference

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The B subunit of the DNA polymerase alpha-primase complex in Saccharomyces cerevisiae executes an essential function at the initial stage of DNA replication

24 September 2017

1 reference

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A new vital stain for visualizing vacuolar membrane dynamics and endocytosis in yeast

24 September 2017

1 reference

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Putative GTP-binding protein, Gtr1, associated with the function of the Pho84 inorganic phosphate transporter in Saccharomyces cerevisiae

24 September 2017

1 reference

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Regulation of translational effectors by amino acid and mammalian target of rapamycin signaling pathways. Possible involvement of autophagy in cultured hepatoma cells

24 September 2017

1 reference

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Opposite effects of tor1 and tor2 on nitrogen starvation responses in fission yeast

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656621

Fission yeast Tor2 promotes cell growth and represses cell differentiation.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656621

Amino acid signaling to TOR activation: Vam6 functioning as a Gtr1 GEF.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656621

Genetic control of cellular quiescence in S. pombe

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656621

Rapamycin sensitivity of the Schizosaccharomyces pombe tor2 mutant and organization of two highly phosphorylated TOR complexes by specific and common subunits

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656621

Fission yeast Tor2 links nitrogen signals to cell proliferation and acts downstream of the Rheb GTPase.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656621

Regulation of leucine uptake by tor1+ in Schizosaccharomyces pombe is sensitive to rapamycin

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656621

Mitochondrial growth and DNA synthesis occur in the absence of nuclear DNA replication in fission yeast

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22344254

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22344254

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1242/JCS.094219

1 reference

23 September 2017

1 reference

23 September 2017

PubMed publication ID

22344254

1 reference