Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity. (Q40789234)

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9 November 2019

title

Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity (English)

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9 November 2019

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10

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9 November 2019

author name string

Ichikawa K

1

1 reference

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9 November 2019

Liu W

2

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9 November 2019

Zhao L

3

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9 November 2019

Wang Z

4

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9 November 2019

Liu D

5

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9 November 2019

Ohtsuka T

6

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9 November 2019

Zhang H

7

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9 November 2019

Mountz JD

8

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9 November 2019

Koopman WJ

9

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9 November 2019

Zhou T

11

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9 November 2019

language of work or name

English

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publication date

1 August 2001

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9 November 2019

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9 November 2019

volume

7

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9 November 2019

issue

8

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9 November 2019

page(s)

954-960

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https://scigraph.springernature.com/pub.10.1038/91000

9 November 2019

exact match

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cites work

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Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors

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Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

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Safety and antitumor activity of recombinant soluble Apo2 ligand

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Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway

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7 January 2021

TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB

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7 January 2021

An antagonist decoy receptor and a death domain-containing receptor for TRAIL

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Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family

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The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain

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Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL.

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Dominant-negative FADD inhibits TNFR60-, Fas/Apo1- and TRAIL-R/Apo2-mediated cell death but not gene induction

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TRAIL causes cleavage of bid by caspase-8 and loss of mitochondrial membrane potential resulting in apoptosis in BJAB cells

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7 January 2021

TRAIL receptor-2 signals apoptosis through FADD and caspase-8

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FADD is required for DR4- and DR5-mediated apoptosis: lack of trail-induced apoptosis in FADD-deficient mouse embryonic fibroblasts

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7 January 2021

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

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7 January 2021

Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

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TRAIL/Apo2L activates c-Jun NH2-terminal kinase (JNK) via caspase-dependent and caspase-independent pathways

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JNK/SAPK activity contributes to TRAIL-induced apoptosis

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Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy

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Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand

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7 January 2021

Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions

1 reference

7 January 2021

Identifiers

DOI

10.1038/91000

1 reference

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9 November 2019

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