Genetic and immunochemical evidence for CD4-dependent association of p56lck with the alpha beta T-cell receptor (TCR): regulation of TCR-induced activation. (Q40790413)

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English	Genetic and immunochemical evidence for CD4-dependent association of p56lck with the alpha beta T-cell receptor (TCR): regulation of TCR-induced activation.	scientific article

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28 October 2019

Genetic and immunochemical evidence for CD4-dependent association of p56lck with the alpha beta T-cell receptor (TCR): regulation of TCR-induced activation (English)

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28 October 2019

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28 October 2019

Pilar Portolés

7

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28 October 2019

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Díez-Orejas R

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28 October 2019

Ballester S

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28 October 2019

Feito MJ

3

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28 October 2019

Ojeda G

4

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28 October 2019

Ronda M

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28 October 2019

Rojo JM

8

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28 October 2019

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1 January 1994

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28 October 2019

The EMBO Journal

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28 October 2019

13

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28 October 2019

1

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28 October 2019

90-99

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28 October 2019

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

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24 September 2017

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

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24 September 2017

T Cell Subsets and the Recognition of MHC Class

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24 September 2017

Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen-Reactivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

24 September 2017

Both a monoclonal antibody and antisera specific for determinants unique to individual cloned helper T cell lines can substitute for antigen and antigen-presenting cells in the activation of T cells

1 reference

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24 September 2017

Direct interactions between B and T lymphocytes bearing complementary receptors

1 reference

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24 September 2017

Cell-cell adhesion mediated by CD8 and MHC class I molecules

1 reference

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24 September 2017

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

24 September 2017

Molecular dynamics in the membranes of helper T cells

1 reference

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24 September 2017

The role of the T3/antigen receptor complex in T-cell activation

1 reference

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24 September 2017

Interaction between CD4 and class II MHC molecules mediates cell adhesion

1 reference

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24 September 2017

Cross-linking and conformational change in T-cell receptors: role in activation and in repertoire selection

1 reference

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24 September 2017

The co-receptor function of murine CD4.

1 reference

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24 September 2017

Epidermal growth factor binding induces a conformational change in the external domain of its receptor

1 reference

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24 September 2017

T-cell receptor-CD4 physical association in a murine T-cell hybridoma: induction by antigen receptor ligation

1 reference

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24 September 2017

Mutations of the platelet-derived growth factor receptor that cause a loss of ligand-induced conformational change, subtle changes in kinase activity, and impaired ability to stimulate DNA synthesis

1 reference

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24 September 2017

Physical association of CD4 and the T-cell receptor can be induced by anti-T-cell receptor antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

24 September 2017

The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

24 September 2017

CD4+ T cells: specificity and function.

1 reference

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24 September 2017

Identification of an immunodominant region on the I-A beta chain using site-directed mutagenesis and DNA-mediated gene transfer

1 reference

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24 September 2017

A method to detect and characterize point mutations in transcribed genes: amplification and overexpression of the mutant c-Ki-ras allele in human tumor cells

1 reference

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24 September 2017

Inhibition of tyrosine phosphorylation prevents T-cell receptor-mediated signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

24 September 2017

Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

24 September 2017

Adhesion versus coreceptor function of CD4 and CD8: role of the cytoplasmic tail in coreceptor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

24 September 2017

T cell antigen receptor activation pathways: The tyrosine kinase connection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

24 September 2017

Oncogenes and signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

24 September 2017

CD3 stimulation causes phosphorylation of phospholipase C-gamma 1 on serine and tyrosine residues in a human T-cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

24 September 2017

Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase C-gamma 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

24 September 2017

Profound block in thymocyte development in mice lacking p56lck

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

24 September 2017

The T cell receptor as a multicomponent signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

24 September 2017

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

24 September 2017

Differential regulation of T cell antigen responsiveness by isoforms of the src-related tyrosine protein kinase p59fyn

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

24 September 2017

Molecular associations between the T-lymphocyte antigen receptor complex and the surface antigens CD2, CD4, or CD8 and CD5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

24 September 2017

Mac-1: a macrophage differentiation antigen identified by monoclonal antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

24 September 2017

Association of CD8 with p56lck is required for early T cell signalling events.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

25 September 2017

The role of the murine L3T4 molecule in T cell activation: differential effects of anti-L3T4 on activation by monoclonal anti-receptor antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

25 September 2017

Polymorphism in the alpha 3 domain of HLA-A molecules affects binding to CD8.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

25 September 2017

The biologic activity of anti-T cell receptor V region monoclonal antibodies is determined by the epitope recognized.

1 reference

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25 September 2017

Antigens involved in mouse cytolytic T-lymphocyte (CTL)-mediated killing: functional screening and topographic relationship

1 reference

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15 June 2018

Comodulation of CD3 and CD4. Evidence for a specific association between CD4 and approximately 5% of the CD3:T cell receptor complexes on helper T lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

15 June 2018

Asymmetry in the recognition of antigen: self class II MHC and non-self class II MHC molecules by the same T-cell receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

15 June 2018

T cell antigen receptor-mediated activation of phospholipase C requires tyrosine phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

15 June 2018

Regulation of T cell receptor signaling by a src family protein-tyrosine kinase (p59fyn).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

15 June 2018

Molecular associations on the T cell surface correlate with immunological memory.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

15 June 2018

A 32-kD GTP-binding protein associated with the CD4-p56lck and CD8-p56lck T cell receptor complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

15 June 2018

Cellular immunity to HIV activated by CD4 fused to T cell or Fc receptor polypeptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

15 June 2018

The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

15 June 2018

Increase of the Catalytic Activity of Phospholipase C-γ1 by Tyrosine Phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

15 June 2018

Increases in tyrosine phosphorylation are detectable before phospholipase C activation after T cell receptor stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

15 June 2018

Requirement for association of p56lck with CD4 in antigen-specific signal transduction in T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

15 June 2018

Activation of T cells by a tyrosine kinase activation domain in the cytoplasmic tail of CD3 epsilon.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

15 June 2018

The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

15 June 2018

Selective association between MHC class I-restricted T cell receptors, CDS, and activated tyrosine kinases on thymocytes undergoing positive selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

15 June 2018

Physical association of CD4 with the T cell receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

15 June 2018

Differential effect of interleukin 1 on naive and memory CD4+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

15 June 2018

Association of tyrosine kinase p56lck with CD4 inhibits the induction of growth through the alpha beta T-cell receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

15 June 2018

Biochemical identification of a direct physical interaction between the CD4: p56lck and Ti(TcR)/CD3 complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394782

2 December 2018

A tyrosine-phosphorylated 70-kDa protein binds a photoaffinity analogue of ATP and associates with both the zeta chain and CD3 components of the activated T cell antigen receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/7905824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical evidence of the physical association of the majority of CD3 delta chains with the accessory/co-receptor molecules CD4 and CD8 on nonactivated T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7905824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific affinity fractionation of lymphocytes using glass or plastic bead columns

1 reference

https://pubmed.ncbi.nlm.nih.gov/7905824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional activities of antibodies against brain-associated T cell antigens. I. Induction of T cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7905824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Surface antigen expression and immunoglobulin gene rearrangement during mouse pre-B cell development

1 reference

https://pubmed.ncbi.nlm.nih.gov/7905824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth of a cloned helper T cell line induced by a monoclonal antibody specific for the antigen receptor: interleukin 1 is required for the expression of receptors for interleukin 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/7905824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a murine monoclonal antibody specific for an allotypic determinant on T cell antigen receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/7905824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antigen activation of murine T cells induces tyrosine phosphorylation of a polypeptide associated with the T cell antigen receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/7905824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross-linking of the T cell receptor complex with the subset-specific differentiation antigen stimulates interleukin 2 receptor expression in human CD4 and CD8 T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7905824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effective activation of resting mouse T lymphocytes by cross-linking submitogenic concentrations of the T cell antigen receptor with either Lyt-2 or L3T4

1 reference

https://pubmed.ncbi.nlm.nih.gov/7905824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a physical association of CD4 and the CD3: α : β T-cell receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/7905824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal antibodies to murine CD3 epsilon define distinct epitopes, one of which may interact with CD4 during T cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7905824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of L3T4 in T cell activation: L3T4 may be both an Ia-binding protein and a receptor that transduces a negative signal

1 reference

https://pubmed.ncbi.nlm.nih.gov/7905824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural mutations of the T cell receptor zeta chain and its role in T cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7905824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein tyrosine kinase p59fyn is associated with the T cell receptor-CD3 complex in functional human lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7905824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p56lck association with CD4 is required for the interaction between CD4 and the TCR/CD3 complex and for optimal antigen stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7905824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/J.1460-2075.1994.TB06238.X

1 reference

Europe PubMed Central

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28 October 2019

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Europe PubMed Central

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28 October 2019

PubMed publication ID

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28 October 2019

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