The cleavage of Akt/protein kinase B by death receptor signaling is an important event in detachment-induced apoptosis (Q40791166)

23 September 2017

The cleavage of Akt/protein kinase B by death receptor signaling is an important event in detachment-induced apoptosis (English)

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23 September 2017

Bachelder RE

1

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23 September 2017

Wendt MA

2

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23 September 2017

Fujita N

3

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23 September 2017

Tsuruo T

4

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23 September 2017

Mercurio AM

5

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23 September 2017

language of work or name

English

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publication date

19 July 2001

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Journal of Biological Chemistry

23 September 2017

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23 September 2017

276

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23 September 2017

37

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23 September 2017

34702-34707

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Disruption of epithelial cell-matrix interactions induces apoptosis

23 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

The extracellular matrix as a cell survival factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Cellular survival: a play in three Akts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Negative regulation of the forkhead transcription factor FKHR by Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Involvement of FADD and caspase-8 signalling in detachment-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Evidence for a function of death-receptor-related, death-domain-containing proteins in anoikis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Apoptosis-induced cleavage of beta-catenin by caspase-3 results in proteolytic fragments with reduced transactivation potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

The regulation of anoikis: MEKK-1 activation requires cleavage by caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Cleavage and inactivation of antiapoptotic Akt/PKB by caspases during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

A role for Jun-N-terminal kinase in anoikis; suppression by bcl-2 and crmA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

p53 inhibits alpha 6 beta 4 integrin survival signaling by promoting the caspase 3-dependent cleavage of AKT/PKB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Conversion of Bcl-2 to a Bax-like death effector by caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Modulation of cell death by Bcl-XL through caspase interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Oncogenic Ras inhibits Fas ligand-mediated apoptosis by downregulating the expression of Fas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

Transforming activity and mitosis-related expression of the AKT2 oncogene: evidence suggesting a link between cell cycle regulation and oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102806200

21 January 2018

Identifiers

DOI

10.1074/JBC.M102806200

1 reference

23 September 2017

1 reference