Identification of methylated CpG motifs as inhibitors of the immune stimulatory CpG motifs. (Q40794617)

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9 November 2019

title

Identification of methylated CpG motifs as inhibitors of the immune stimulatory CpG motifs (English)

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9 November 2019

2

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9 November 2019

author name string

Chen Y

1

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9 November 2019

Weeratna R

3

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9 November 2019

McCluskie M

4

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9 November 2019

Wu T

5

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9 November 2019

Davis HL

6

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9 November 2019

Krieg AM

7

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9 November 2019

publication date

1 July 2001

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9 November 2019

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9 November 2019

volume

8

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9 November 2019

page(s)

1024-1032

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9 November 2019

issue

13

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https://scigraph.springernature.com/pub.10.1038/sj.gt.3301482

9 November 2019

exact match

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cites work

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CpG motifs in bacterial DNA trigger direct B-cell activation

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Immunostimulatory DNA sequences necessary for effective intradermal gene immunization

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Comparison of DNA-lipid complexes and DNA alone for gene transfer to cystic fibrosis airway epithelia in vivo

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CpG motifs in bacterial DNA cause inflammation in the lower respiratory tract

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Reduced inflammatory response to plasmid DNA vectors by elimination and inhibition of immunostimulatory CpG motifs

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Inhibition of murine macrophage IL-12 production by natural and synthetic DNA.

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Binding of oligoguanylate to scavenger receptors is required for oligonucleotides to augment NK cell activity and induce IFN.

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Macrophages sense pathogens via DNA motifs: induction of tumor necrosis factor-alpha-mediated shock

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Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization

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Promoter attenuation in gene therapy: interferon-gamma and tumor necrosis factor-alpha inhibit transgene expression

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Interferon-gamma inhibits transgene expression driven by SV40 or CMV promoters but augments expression driven by the mammalian MHC I promoter

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Cancer gene therapy using plasmid DNA: safety evaluation in rodents and non-human primates

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Requirements for effective inhibition of immunostimulatory CpG motifs by neutralizing motifs.

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Immune-mediated destruction of transfected muscle fibers after direct gene transfer with antigen-expressing plasmid DNA.

21 January 2018

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New pUC-derived cloning vectors with different selectable markers and DNA replication origins.

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Transcriptional repression by methylation: cooperativity between a CpG cluster in the promoter and remote CpG-rich regions

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Bacterial DNA causes septic shock

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Contribution of Plasmid DNA to Inflammation in the Lung after Administration of Cationic Lipid:pDNA Complexes

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7 January 2021

Intra-articularly localized bacterial DNA containing CpG motifs induces arthritis

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7 January 2021

Ca2+-ATPases and their expression in the mammary gland of pregnant and lactating rats

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7 January 2021

The inhibitory role of CpG immunostimulatory motifs in cationic lipid vector-mediated transgene expression in vivo

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7 January 2021

Simultaneous introduction of multiple mutations using overlap extension PCR

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7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3301482

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11438837%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 November 2019

0 references

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