Synergistic effects of pi3k/akt on abrogation of cytokine-dependency induced by oncogenic raf. (Q40802206)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11384752%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

title

Synergistic effects of pi3k/akt on abrogation of cytokine-dependency induced by oncogenic raf (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11384752%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11384752%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

William Blalock

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11384752%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Richard A. Franklin

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11384752%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

author name string

L S Steelman

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11384752%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

J T Lee

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11384752%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

P W Moye

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11384752%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

F Chang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11384752%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

M Pearce

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11384752%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

J G Shelton

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11384752%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

M K White

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11384752%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

S C Pohnert

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11384752%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

publication date

1 January 2001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11384752%20AND%20SRC:MED&resulttype=core&format=json

Advances in Enzyme Regulation

8 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11384752%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

volume

41

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11384752%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

page(s)

289-323

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11384752%20AND%20SRC:MED&resulttype=core&format=json

Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells: possible sites for intervention with anti-neoplastic drugs

8 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Differential effects of retroviral long terminal repeats on interleukin-3 gene expression and autocrine transformation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Growth of factor-dependent hemopoietic precursor cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Enrichment of hematopoietic precursor cells and cloning of multipotential B-lymphocyte precursors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

A conditionally-active form of MEK1 results in autocrine tranformation of human and mouse hematopoietic cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Effects of inducible MEK1 activation on the cytokine dependency of lymphoid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Serine/threonine phosphorylation in cytokine signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Diphtheria toxin fused to human interleukin-3 is toxic to blasts from patients with myeloid leukemias

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Effects of deregulated RAF and MEK1 expression on the cytokine-dependency of hematopoietic cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Combined effects of aberrant MEK1 activity and BCL2 overexpression on relieving the cytokine dependency of human and murine hematopoietic cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Synergy between Raf and BCL2 in abrogating the cytokine dependency of hematopoietic cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Kinases: positive and negative regulators of apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Signaling through the hematopoietic cytokine receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Apoptosis meets signal transduction: elimination of a BAD influence

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Bcl-2 associates with the ras-related protein R-ras p23

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Bcl-2 targets the protein kinase Raf-1 to mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Beta interferon and oncostatin M activate Raf-1 and mitogen-activated protein kinase through a JAK1-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Interferon gamma activation of Raf-1 is Jak1-dependent and p21ras-independent

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Mechanisms regulating Raf-1 activity in signal transduction pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Drosophila melanogaster homologs of the raf oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Raf-1 protein is required for growth factor-induced proliferation of hematopoietic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Post-natal lethality and neurological and gastrointestinal defects in mice with targeted disruption of the A-Raf protein kinase gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Endothelial apoptosis in Braf-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Craf-1 protein kinase is essential for mouse development.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Definition of the human raf amino-terminal regulatory region by deletion mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Conditionally oncogenic forms of the A-Raf and B-Raf protein kinases display different biological and biochemical properties in NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Mutations of critical amino acids affect the biological and biochemical properties of oncogenic A-Raf and Raf-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Critical Tyrosine Residues Regulate the Enzymatic and Biological Activity of Raf-1 Kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Transformation of mammalian cells by constitutively active MAP kinase kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Transcriptional regulation by MAP kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Phosphoinositide 3-kinases: a conserved family of signal transducers

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

The modular phosphorylation and activation of p70s6k.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Interleukin 3-dependent survival by the Akt protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: involvement of MEK upstream of Bad phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Phosphatidylinositol 3-OH kinase activity is not required for activation of mitogen-activated protein kinase by cytokines

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Regulation of bad phosphorylation and association with Bcl-x(L) by the MAPK/Erk kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Role of phosphatidylinositol 3-OH-kinase activity in the inhibition of apoptosis in haemopoietic cells: phosphatidylinositol 3-OH-kinase inhibitors reveal a difference in signalling between interleukin-3 and granulocyte-macrophage colony stimulating

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Dissociation of apoptosis from proliferation, protein kinase B activation, and BAD phosphorylation in interleukin-3-mediated phosphoinositide 3-kinase signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Role of phosphoinositide 3-kinase in activation of ras and mitogen-activated protein kinase by epidermal growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

A phosphatidylinositol 3-kinase-dependent pathway that differentially regulates c-Raf and A-Raf

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Phosphorylation and regulation of Raf by Akt (protein kinase B)

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Malignant transformation of a growth factor-dependent myeloid cell line by Abelson virus without evidence of an autocrine mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Neoplastic transformation of mast cells by Abelson-MuLV: abrogation of IL-3 dependence by a nonautocrine mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Abelson virus abrogation of interleukin-3 dependence in a lymphoid cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Signal transduction through the EGF receptor transfected in IL-3-dependent hematopoietic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

The v-fms oncogene induces factor-independent growth and transformation of the interleukin-3-dependent myeloid cell line FDC-P1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Induction of macrophage colony-stimulating factor-dependent growth and differentiation after introduction of the murine c-fms gene into FDC-P1 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Nature and specificity of lymphokine independence induced by a selectable retroviral vector expressing v-src

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

A retrovirus encoding the v-fps protein-tyrosine kinase induces factor-independent growth and tumorigenicity in FDC-P1 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

A temperature sensitive p210 BCR-ABL mutant defines the primary consequences of BCR-ABL tyrosine kinase expression in growth factor dependent cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Transfection of the bcr/abl oncogene into factor-dependent cells by electroporation: acquisition of autonomous proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Jak-STAT signaling induced by the v-abl oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

P210 and P190(BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Constitutive activation of JAK1 in Src-transformed cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900021-2

7 January 2021

10.1016/S0065-2571(00)00021-2

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11384752%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

1 reference